Positional specificity of saturated and unsaturated fatty acids in phosphatidic acid from rat liver [PDF]
Lipids and Lipid Metabolism, 1969 1. 1. The relative incorporation of a number of radioactive fatty acids into the different glycerolipids of rat liver microsomes has been investigated. 2. 2.
L M G van Golde +2 more
exaly +3 more sources
Regulation of mTOR by Phosphatidic Acid
Trends in Endocrinology & Metabolism, 2023 mTORC1, the mammalian target of rapamycin complex 1, is a key regulator of cellular physiology. The lipid metabolite phosphatidic acid (PA) binds to and activates mTORC1 in response to nutrients and growth factors. Here, we review structural findings and
M. Frias, A. Hatipoglu, D. A. Foster
semanticscholar +3 more sources
Definitions, 2020 A glycerol backbone covalently bound to a phosphate group in one position, and fatty acids in the 2nd and 3rd positions. Phosphatidic acids thus have a polar head and apolar tails, and occur in cell membranes throughout nature.
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Cytotoxicity mechanism of heterologous expression of phospholipase D in Escherichia coli [PDF]
Microbiology SpectrumPhospholipase D (PLD) has multiple functions in cells and various industrial applications, including the production of high-purity and rare phospholipids, making it a highly valuable enzyme.
Shaofeng Chen +5 more
doaj +2 more sources
The enzymatic dephosphorylation of phosphatidic acids.
Journal of Biological Chemistry, 1957 Enzyme systems from rat and guinea pig liver which carry out a rapid synthesis of phosphatidic acid have been described by Kornberg and Pricer (l), Kennedy (2), and others.
Sylvia Wagner Smith +2 more
semanticscholar +3 more sources
Multiplex FAD2/FATB Editing Generates Ultra-High-Oleic, Low-Saturate Soybean With Increased Seed Fatty Acid Content. [PDF]
Plant Biotechnol JABSTRACT Oleic acid (18:1), saturated fatty acid (SFA), and polyunsaturated fatty acid (PUFA) levels are important traits for storage stability and edibility. In this study, we aimed to develop high‐oleic soybean (Glycine max) by simultaneously targeting fatty acid desaturase 2 (FAD2) and fatty acyl‐ACP thioesterase B (FATB) gene families using CRISPR ...
Kim WN +4 more
europepmc +2 more sources
Preliminary Study on Nutritional Value and Biologically Active Components of Kidney Vetch (Anthyllis vulneraria L.) [PDF]
PlantsThe aim of the current study is to determine the nutritional value and the content of the biologically active components in kidney vetch (Anthyllis vulneraria L.).
Olga Teneva +10 more
doaj +2 more sources
Optical Control of Phosphatidic Acid Signaling [PDF]
ACS Central Science, 2021 Phosphatidic acids (PAs) are glycerophospholipids that regulate key cell signaling pathways governing cell growth and proliferation, including the mTOR and Hippo pathways.
Reika Tei +4 more
semanticscholar +5 more sources
Saturated phosphatidic acids mediate saturated fatty acid-induced vascular calcification and lipotoxicity. [PDF]
J Clin Invest, 2015 Masuda M +9 more
europepmc +2 more sources
Phosphatidic Acid Synthesis in Bacteria [PDF]
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2012 Membrane phospholipid synthesis is a vital facet of bacterial physiology. Although the spectrum of phospholipid headgroup structures produced by bacteria is large, the key precursor to all of these molecules is phosphatidic acid (PtdOH).
Jiangwei Yao, C. Rock
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