Results 11 to 20 of about 18,012 (195)

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

open access: yesHepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario   +12 more
wiley   +1 more source

Apparent convergence (at 2-monoacylglycerol level) of phosphatidic acid and 2-monoacylglycerol pathways of synthesis of chylomicron triacylglycerols.

open access: yesJournal of Lipid Research, 1991
Dietary fats are converted into chylomicron triacylglycerols via the 2-monoacylglycerol and phosphatidic acid pathways of acylglycerol formation. In view of the known positional and fatty acid specificity of the acyltransferases, the triacylglycerol ...
LY Yang, A Kuksis
doaj   +1 more source

Phosphatidic acid in membrane rearrangements [PDF]

open access: yesFEBS Letters, 2019
Phosphatidic acid (PA) is the simplest cellular glycerophospholipid characterized by unique biophysical properties: a small headgroup; negative charge; and a phosphomonoester group. Upon interaction with lysine or arginine, PA charge increases from −1 to −2 and this change stabilizes protein–lipid interactions.
Zhukovsky Mikhail A   +4 more
openaire   +3 more sources

Hydrolysis of long-chain alkyl phosphates and phosphatidic acid by an enzyme purified from pig brain*†

open access: yesJournal of Lipid Research, 1962
Particulate preparations of rat and pig tissues have been found to catalyze the hydrolysis of lipid phosphates including many alcohol dihydrogen phosphates as well as phosphatidic acids.
Bernard W. Agranoff
doaj   +1 more source

PHOSPHATIDIC ACID SYNTHESIS IN YEAST [PDF]

open access: yesBiochemical Journal, 1965
1. The presence of palmitoyl-CoA-l-glycerol 1-phosphate palmitoyltransferase (EC2.3.1.15) has been demonstrated in a particulate fraction of baker's yeast. 2. The enzyme has been characterized, and its activity studied as a function of pH and concentration of substrates. 3. Inhibition by thiol poisons and protection by acyl-CoA have been used to obtain
N J, KUHN, F, LYNEN
openaire   +2 more sources

Fat metabolism in higher plants: XIII. phosphatidic acid synthesis and diglyceride phosphokinase activity in mitochondria from peanut cotyledons*

open access: yesJournal of Lipid Research, 1960
A phosphatidic acid is the major lipid to become labeled when Pi32 (inorganic orthophosphate labeled with P32), under conditions of oxidative phosphorylation, or ATP32 is fed to mito-choline and phosphatidylethanolamine in the mitochondria obtained a ...
Clive Bradbeer, P.K. Stumpf
doaj   +1 more source

Characterization of key enzymes involved in triacylglycerol biosynthesis in mycobacteria

open access: yesScientific Reports, 2021
Phosphatidic acid phosphatase (PAP) catalyzes the dephosphorylation of phosphatidic acid (PA) yielding diacylglycerol (DAG), the lipid precursor for triacylglycerol (TAG) biosynthesis.
Agostina Crotta Asis   +4 more
doaj   +1 more source

Insights Into Walnut Lipid Metabolism From Metabolome and Transcriptome Analysis

open access: yesFrontiers in Genetics, 2021
Walnut oil is an excellent source of essential fatty acids. Systematic evaluation of walnut lipids has significance for the development of the nutritional and functional value of walnut.
Suxian Yan   +12 more
doaj   +1 more source

Mitochondria: Signaling with phosphatidic acid [PDF]

open access: yesThe International Journal of Biochemistry & Cell Biology, 2012
Mitochondria, once viewed as functioning relatively autonomously in the cell, have increasingly been recognized to be involved in numerous signaling networks that impact on a wide range of cell biological processes. In addition to the many types of proteins that mediate these pathways, the importance of signaling functions regulated via lipids and ...
Chia-Ying, Yang, Michael A, Frohman
openaire   +2 more sources

Optical Control of Phosphatidic Acid Signaling [PDF]

open access: yesACS Central Science, 2021
Phosphatidic acids (PAs) are glycerophospholipids that regulate key cell signaling pathways governing cell growth and proliferation, including the mTOR and Hippo pathways. Their acyl chains vary in tail length and degree of saturation, leading to marked differences in the signaling functions of different PA species.
Reika Tei   +4 more
openaire   +4 more sources

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