Results 21 to 30 of about 19,316 (249)

Cyclic Phosphatidic Acid Relieves Osteoarthritis Symptoms [PDF]

Molecular Pain, 2014
Background: Cyclic phosphatidic acid (cPA) is a naturally occurring phospholipid mediator with a unique cyclic phosphate ring at the sn-2 and sn-3 positions of its glycerol backbone. Natural cPA and its chemically stabilized cPA derivative, 2-carba-cPA (2ccPA), inhibit chronic and acute inflammation, and 2ccPA attenuates neuropathic pain ...
Gotoh, Mari, Nagano, Aya, Tsukahara, Ryoko, Murofushi, Hiromu, Morohoshi, Toshiro, Otsuka, Kazuyuki, Murakami-Murofushi, Kimiko   +6 more
openaire   +2 more sources

Modulation of 1,25-dihydroxyvitamin D3 receptor by phospholipids and fatty acids.

Journal of Lipid Research, 1984
The structural relationship between several lipids and their respective capacities to inhibit the specific binding of [3H]-1,25 (OH)2 vitamin D3 to chick intestinal cytosol preparations was investigated.
T C Chen, J P Mullen, N J Meglin
doaj   +1 more source

Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate

Nature Communications, 2018
The acetyltransferase Tip60 mediates signaling pathways by acetylating non-histone proteins. Here the authors show that fatty acids induce Tip60–dependent acetylation of phosphatidic acid phosphatase lipin1 which, then, translocates to the ER and ...
Terytty Yang Li, Lintao Song, Yu Sun, Jingyi Li, Cong Yi, Sin Man Lam, Dijin Xu, Linkang Zhou, Xiaotong Li, Ying Yang, Chen-Song Zhang, Changchuan Xie, Xi Huang, Guanghou Shui, Shu-Yong Lin, Karen Reue, Sheng-Cai Lin   +16 more
doaj   +1 more source

Acceptors of fatty acid for glyceride synthesis in guinea pig mammary gland

Journal of Lipid Research, 1964
Glycerides are shown to be synthesized by two pathways in mammary tissue of lactating guinea pigs. One pathway involves the direct acylation of monoglycerides.
O.W. McBride, Edward D. Korn
doaj   +1 more source

Bioactive lipids in gintonin-enriched fraction from ginseng

Journal of Ginseng Research, 2019
Background: Ginseng is a traditional herbal medicine for human health. Ginseng contains a bioactive ligand named gintonin. The active ingredient of gintonin is lysophosphatidic acid C18:2 (LPA C18:2).
Hee-Jung Cho, Sun-Hye Choi, Hyeon-Joong Kim, Byung-Hwan Lee, Hyewon Rhim, Hyoung-Chun Kim, Sung-Hee Hwang, Seung-Yeol Nah   +7 more
doaj   +1 more source

Lipid composition of Evonimus japonicus L., Piracanttia coccinea L. and Amelanchier cannadensis L. seed oils

Grasas y Aceites, 1999
Lipid composition of Evonimus japonicus L., Piracantha coccinea L. and Amelanchier cannadensis L. seed oils. The seeds of Evonimus japonicus L., Piracantha coccinea L. and Amelanchier cannadensis L. contained 45.4%, 3.7% and 7.2% oil respectively. Oleic,
M. Zlatanov, P. Vazvazova
doaj   +1 more source

Staphylococcus aureus Lipase 3 (SAL3) is a surface-associated lipase that hydrolyzes short chain fatty acids.

PLoS ONE, 2021
Bacterial lipases play important roles during infection. The Staphylococcus aureus genome contains several genes that encode well-characterized lipases and several genes predicted to encode lipases or esterases for which the function has not yet been ...
Naren Gajenthra Kumar, Daniel Contaifer, Dayanjan S Wijesinghe, Kimberly K Jefferson   +3 more
doaj   +1 more source

Nanoparticle‐Based Tolerogenic Vaccines: Next‐Generation Strategies for Autoimmune and Allergic Disease Therapies

Angewandte Chemie, EarlyView.
Nanoparticle‐based tolerogenic vaccines harness controlled antigen delivery and immunomodulation to establish tolerance in autoimmunity and allergy. This review outlines how nanoparticle design (size, shape, composition, administration route) influences biodistribution and immune‐cell targeting.
Benjamin E. Nachod, Ajay S. Thatte, Rohan Palanki, Michael J. Mitchell   +3 more
wiley   +2 more sources

Levels of Arabidopsis thaliana leaf phosphatidic acids, phosphatidylserines, and most trienoate-containing polar lipid molecular species increase during the dark period of the diurnal cycle

Frontiers in Plant Science, 2012
Previous work has demonstrated that plant leaf polar lipid fatty acid composition varies during the diurnal (dark-light) cycle. Fatty acid synthesis occurs primarily during the light, but fatty acid desaturation continues in the absence of light ...
Sara eMaatta, Brad eScheu, Mary R. Roth, Pamela eTamura, Maoyin eLi, Maoyin eLi, Todd D. Williams, Xuemin eWang, Xuemin eWang, Ruth eWelti   +9 more
doaj   +1 more source

Origin of triacylglycerol moiety of plasma very low density lipoproteins in the rat: structural studies

Journal of Lipid Research, 1995
We have compared the molecular species composition of the glycerolipids of rat liver and rat plasma very low density lipoproteins (VLDL). There were differences in the stereospecific distribution of the fatty acids in the triacylglycerols (TG) of the ...
L Y Yang, A Kuksis, J J Myher, G Steiner
doaj   +1 more source