Results 11 to 20 of about 33,560 (288)

Fasting increases 18:2-containing phosphatidylcholines to complement the decrease in 22:6-containing phosphatidylcholines in mouse skeletal muscle.

PLoS ONE, 2021
Fasting stimulates catabolic reactions in skeletal muscle to survive nutrient deprivation. Cellular phospholipids have large structural diversity due to various polar-heads and acyl-chains that affect many cellular functions. Skeletal muscle phospholipid
Nanami Senoo, Takumi Akahori, Hiyori Ichida, Noriyuki Miyoshi, Akihito Morita, Takao Shimizu, Hideo Shindou, Shinji Miura   +7 more
doaj   +1 more source

Elevated Free Phosphatidylcholine Levels in Cerebrospinal Fluid Distinguish Bacterial from Viral CNS Infections

Cells, 2021
The identification of CSF biomarkers for bacterial meningitis can potentially improve diagnosis and understanding of pathogenesis, and the differentiation from viral CNS infections is of particular clinical importance.
Amani Al-Mekhlafi, Kurt-Wolfram Sühs, Sven Schuchardt, Maike Kuhn, Kirsten Müller-Vahl, Corinna Trebst, Thomas Skripuletz, Frank Klawonn, Martin Stangel, Frank Pessler   +9 more
doaj   +1 more source

The human plasma-metabolome: Reference values in 800 French healthy volunteers; impact of cholesterol, gender and age. [PDF]

PLoS ONE, 2017
Metabolomic approaches are increasingly used to identify new disease biomarkers, yet normal values of many plasma metabolites remain poorly defined. The aim of this study was to define the "normal" metabolome in healthy volunteers. We included 800 French
Séverine Trabado, Abdallah Al-Salameh, Vincent Croixmarie, Perrine Masson, Emmanuelle Corruble, Bruno Fève, Romain Colle, Laurent Ripoll, Bernard Walther, Claire Boursier-Neyret, Erwan Werner, Laurent Becquemont, Philippe Chanson   +12 more
doaj   +1 more source

Rapid semi-quantification of triacylglycerols, phosphatidylcholines, and free fatty acids in the rice bran of one grain

Journal of Integrative Agriculture, 2018
We developed a microplate assay method for determining the contents of triacylglycerols (TAGs), phosphatidylcholines (PCs), and free fatty acids (FFAs) in the rice bran of one grain using enzymatic reactions.
Junko Nagamoto, Ai Sawazaki, Motonori Miyago, Bungo Shirouchi, Mitsukazu Sakata, Li-tao TONG, Toshihiro Kumamaru, Masao Sato   +7 more
doaj   +1 more source

Structural identification of oxidized acyl-phosphatidylcholines that induce platelet activation [PDF]

, 2005
Oxidation of low-density lipoprotein (LDL) generates proinflammatory and prothrombotic mediators that may play a crucial role in cardiovascular and inflammatory diseases.
Berliner JA, Bittman R, Casals-Stenzal J, Esterbauer H, Fernandez-Ortiz A, Frey B, Goetzl EJ, Holvoet P, Itabe H, Kamido H, Kamido H, Kern H, Kinsella BT, Kitagawa S, O'Flaherty JT, O'Flaherty JT, Rasmussen UB, Sevanian A, Subbanagounder G, Tanaka T, Trip MD, Volf I, Watson AD, Weidtmann A   +23 more
core   +1 more source

Longitudinal Metabolomic Profiling of Amino Acids and Lipids across Healthy Pregnancy [PDF]

, 2015
Pregnancy is characterized by a complexity of metabolic processes that may impact fetal development and ultimately, infant health outcomes. However, our understanding of whole body maternal and fetal metabolism during this critical life stage remains ...
Ashton, Nick, Buss, Claudia, Entringer, Sonja, Hellmuth, Christian, Koletzko, Berthold, Lindsay, Karen L, Uhl, Olaf, Wadhwa, Pathik D   +7 more
core   +10 more sources

Functional role of water in membranes updated: A tribute to Träuble [PDF]

, 2015
The classical view of a cell membrane is as a hydrophobic slab in which only nonpolar solutes can dissolve and permeate. However, water-soluble non-electrolytes such as glycerol, erythritol, urea and others can permeate lipid membranes in the liquid ...
Bouchet, Ana María, Disalvo, Edgardo Anibal, Frías, María de los Ángeles, Hollmann, Axel, Martini, María Florencia, Pinto, Oscar Alejandro   +5 more
core   +1 more source

Automated workflow-based exploitation of pathway databases provides new insights into genetic associations of metabolite profiles [PDF]

, 2013
Background: Genome-wide association studies (GWAS) have identified many common single nucleotide polymorphisms (SNPs) that associate with clinical phenotypes, but these SNPs usually explain just a small part of the heritability and have relatively modest
Adamski, J. (Jerzy), Aulchenko, Y.S. (Yurii), Axenovich, T.I. (Tatiana), Biloglav, Z. (Zrinka), Broer, L. (Linda), Campbell, H. (Harry), Campbell, S. (Susan), Demirkan, A. (Ayşe), Dharuri, H. (Harish), Domingues, I. (Inês), Duijn, C.M. (Cornelia) van, Floyd, J. (Jamie), Franke, L. (Lude), Franklin, C.S. (Christopher), Gieger, C. (Christian), Gnewuch, C. (Carsten), Gyllensten, U. (Ulf), Hastie, N. (Nick), Hayward, C. (Caroline), Henneman, P. (Peter), Hettne, K.M. (Kristina), Hicks, A.A. (Andrew), Hoen, P.A.C. (Peter) 't, Hofman, A. (Albert), Huffman, J.E. (Jennifer), Igl, W. (Wilmar), Isaacs, A.J. (Aaron), Jansen, R.C. (Ritsert), Janssens, A.C.J.W. (Cécile), Johansson, A. (Åsa), Jonasson, I. (Inger), Karssen, L.C. (Lennart), Kirichenko, A.V. (Anatoly), Klinken, J.B. (Jan) van, Kolcic, I. (Ivana), Liebisch, G. (Gerhard), Meitinger, T. (Thomas), Mook-Kanamori, D.O. (Dennis), Oostra, B.A. (Ben), Pattaro, C. (Cristian), Pfeufer, A. (Arne), Pichler, I. (Irene), Polasek, O. (Ozren), Pramstaller, P.P. (Peter Paul), Rivadeneira Ramirez, F. (Fernando), Roos, M. (Marco), Rudan, I. (Igor), Schmitz, G. (Gerd), Struchalin, M.V. (Maksim), Suhre, K. (Karsten), Ugocsai, P. (Peter), Uitterlinden, A.G. (André), Vitart, V. (Veronique), Wang-Sattler, R. (Rui), Wild, S.H. (Sarah), Willems van Dijk, J.A.P. (Ko), Wilson, J.F. (James F), Witteman, J.C.M. (Jacqueline), Wright, A.F. (Alan), Zaboli, G. (Ghazal), Zorkoltseva, I.V. (Irina)   +60 more
core   +1 more source

p73α1, an Isoform of the p73 Tumor Suppressor, Modulates Lipid Metabolism and Cancer Cell Growth via Stearoyl-CoA Desaturase-1

Cells, 2022
Altered lipid metabolism is a hallmark of cancer. p73, a p53 family member, regulates cellular processes and is expressed as multiple isoforms. However, the role of p73 in regulating lipid metabolism is not well-characterized.
Zachary Rabow, Kyra Laubach, Xiangmudong Kong, Tong Shen, Shakur Mohibi, Jin Zhang, Oliver Fiehn, Xinbin Chen   +7 more
doaj   +1 more source

Decreased Hyocholic Acid and Lysophosphatidylcholine Induce Elevated Blood Glucose in a Transgenic Porcine Model of Metabolic Disease

Metabolites, 2022
(1) Background: This work aims to investigate the metabolomic changes in PIGinH11 pigs and investigate differential compounds as potential therapeutic targets for metabolic diseases.
Jianping Xu, Kaiyi Zhang, Bintao Qiu, Jieying Liu, Xiaoyu Liu, Shulin Yang, Xinhua Xiao   +6 more
doaj   +1 more source