Results 11 to 20 of about 74,308 (377)

Phase behaviour of dehydrated phosphatidylcholines [PDF]

Journal of Thermal Analysis and Calorimetry, 2016
Dehydrated DLPC, DMPC, DPPC and DSPC have been characterised at temperatures below the diacyl carbon chain-melting transition (Tm), using DSC. For the first time, the existence of pre-Tm transition processes, which are, usually, only observed in the ...
Samuel K. Owusu-Ware, B. Chowdhry, S. Leharne, M. Antonijević   +3 more
semanticscholar   +2 more sources

Genetic causality of lipidomic and immune cell profiles in ischemic stroke [PDF]

Frontiers in Neurology
BackgroundIschemic stroke (IS) is a global health issue linked to lipid metabolism and immune cell responses. This study uses Mendelian randomization (MR) to identify genetic risk factors for IS subtypes using comprehensive genetic data from lipidomic ...
Haohao Chen, Haohao Chen, Zequn Zheng, Zequn Zheng, Xiaorui Cai, Shunxian Li, Manli Chen, Jiaming Wu, Wenzhen He, Fenfei Gao   +9 more
doaj   +2 more sources

Lipidomic analysis reveals metabolism alteration associated with subclinical carotid atherosclerosis in type 2 diabetes [PDF]

Cardiovascular Diabetology
Background Disruption of lipid metabolism contributes to increased cardiovascular risk in diabetes. Methods We evaluated the associations between serum lipidomic profile and subclinical carotid atherosclerosis (SCA) in type 1 (T1D) and type 2 (T2D ...
Maria Barranco-Altirriba, Joana Rossell, Núria Alonso, Ralf J. M. Weber, Emilio Ortega, Gavin R. Lloyd, Marta Hernandez, Oscar Yanes, Jordi Capellades, Catherine Winder, Alexandra Junza, Mireia Falguera, Josep Franch-Nadal, Warwick B. Dunn, Alexandre Perera-Lluna, Esmeralda Castelblanco, Didac Mauricio   +16 more
doaj   +2 more sources

Miscibility of Sphingomyelins and Phosphatidylcholines in Unsaturated Phosphatidylcholine Bilayers [PDF]

Biophysical Journal, 2015
Polyunsaturated phospholipids are common in biological membranes and affect the lateral structure of bilayers. We have examined how saturated sphingomyelin (SM; palmitoyl and stearoyl SM (PSM and SSM, respectively)) and phosphatidylcholine (PC; dipalmitoyl PC and 1-palmitoyl-2-stearoyl PC (DPPC and PSPC, respectively)) segregate laterally to form ...
Anders Kullberg, J. Peter Slotte, Oscar Oz Ekholm   +2 more
openaire   +3 more sources

Associations of Early Pregnancy Metabolite Profiles with Gestational Blood Pressure Development

Metabolites, 2022
Blood pressure development plays a major role in both the etiology and prediction of gestational hypertensive disorders. Metabolomics might serve as a tool to identify underlying metabolic mechanisms in the etiology of hypertension in pregnancy and lead ...
Sophia M. Blaauwendraad, Rama J. Wahab, Bas B. van Rijn, Berthold Koletzko, Vincent W. V. Jaddoe, Romy Gaillard   +5 more
doaj   +1 more source

High level of phosphatidylcholines/lysophosphatidylcholine ratio in urine is associated with prostate cancer

Cancer Science, 2021
The altered levels of phospholipids (PLs) and lysophospholipids (LPLs) in prostate cancer (CaP) and benign tissues in our previous findings prompted us to explore PLs and LPLs as potential biomarkers for CaP.
Xin Li, K. Nakayama, Takayuki Goto, H. Kimura, S. Akamatsu, Y. Hayashi, Ken-Ichi Fujita, Takashi Kobayashi, Koji Shimizu, N. Nonomura, O. Ogawa, Takahiro Inoue   +11 more
semanticscholar   +1 more source

The Expanded Endocannabinoid System Contributes to Metabolic and Body Mass Shifts in First-Episode Schizophrenia: A 5-Year Follow-Up Study

Biomedicines, 2022
Alterations in the expanded endocannabinoid system (eECS) and cell membrane composition have been implicated in the pathophysiology of schizophrenia spectrum disorders. We enrolled 54 antipsychotic (AP)-naïve first-episode psychosis (FEP) patients and 58
Madis Parksepp, Liina Haring, Kalle Kilk, Kadri Koch, Kärt Uppin, Raul Kangro, Mihkel Zilmer, Eero Vasar   +7 more
doaj   +1 more source

Structure and Interdigitation of Chain-Asymmetric Phosphatidylcholines and Milk Sphingomyelin in the Fluid Phase

Symmetry, 2021
We addressed the frequent occurrence of mixed-chain lipids in biological membranes and their impact on membrane structure by studying several chain-asymmetric phosphatidylcholines and the highly asymmetric milk sphingomyelin.
Moritz P. K. Frewein, M. Doktorova, Frederick A. Heberle, H. L. Scott, E. Semeraro, L. Porcar, G. Pabst   +6 more
semanticscholar   +1 more source

Mucosal Protection by Phosphatidylcholine [PDF]

Digestive Diseases, 2012
The colonic mucus serves a first barrier towards invasion of commensal bacteria in stools to prevent inflammation. One essential component of intestinal mucus is phosphatidylcholine (PC) which represents more than 90% of the phospholipids in mucus indicative for a selective transport of PC into this compartment. It is arranged in lamellar structures as
Stremmel, Wolfgang, Ehehalt, Robert, Staffer, Sabine, Stoffels, Sabine, Mohr, Andrea, Karner, Max, Braun, Annika   +6 more
openaire   +4 more sources

Unique Distribution of Diacyl-, Alkylacyl-, and Alkenylacyl-Phosphatidylcholine Species Visualized in Pork Chop Tissues by Matrix-Assisted Laser Desorption/Ionization–Mass Spectrometry Imaging

Foods, 2020
Phosphatidylcholine (PC) is the major phospholipid in meat and influences meat qualities, such as healthiness. PC is classified into three groups based on the bond at the sn-1 position: Diacyl, alkylacyl, and alkenylacyl. To investigate their composition
Hirofumi Enomoto, Tomohiro Furukawa, Shiro Takeda, Hajime Hatta, Nobuhiro Zaima   +4 more
doaj   +1 more source