Results 31 to 40 of about 19,173 (307)

Functional, transcriptomic, and lipidomic studies of the choC gene encoding a phospholipid methyltransferase in Aspergillus fumigatus

Microbiology Spectrum
Phosphatidylcholines (PCs) are a class of cell membrane phospholipids playing important roles in cellular integrity and signaling. In eukaryotes, PCs are biosynthesized via the Kennedy cytidine nucleotide and the Bremer-Greenberg pathways.
Jiao Pan, Xinyu Yang, Cuiting Hu, Tongtong Fu, Xiuyan Zhang, Zijun Liu, Yu Wang, Fengyu Zhang, Xiaoyuan He, Jae-Hyuk Yu   +9 more
doaj   +1 more source

Molecular species of biliary phosphatidylcholines in gallstone patients: the influence of treatment with cholic acid and chenodeoxycholic acid

Journal of Lipid Research, 1981
Molecular species of phosphatidylcholines were analyzed in hepatic and gallbladder bile obtained from six subjects with adenomyoma of the gallbladder (gallstone-free controls) and 27 gallstone patients undergoing cholecystectomy.
J Ahlberg, T Curstedt, K Einarsson, J Sjövall   +3 more
doaj   +1 more source

Ratio of total lysophosphatidylcholines to total phosphatidylcholines.

, 2015
The displayed concentration values represent the mean of the samples of all 19 participants at the respective pre-analytical condition. The error bars represent one standard deviation based on the 19 measurements.
Cornelia Prehn (137977), Margit Heier (200535), Melanie Waldenberger (236985), Rory Wilson (332489), Bruce Wolfenbuttel (714793), Werner Römisch-Margl (127480), Zhong-hao Yu (5662840), Christa Meisinger (39940), Gabi Kastenmüller (127487), Annette Peters (62601), Rui Wang-Sattler (36841), Kristian Hveem (189996), Jerzy Adamski (127482), Gabriele Anton (714792), Sven Zukunft (697634)   +14 more
core   +1 more source

Modification of concanavalin A-dependent proliferation by phosphatidylcholines isolated from deer antler, Cervus elaphus

, 2020
Objective The immunomodulatory effect of deer antler, which is used as traditional medicine, has been known, but the active component of antlers from Cervus elaphus has not been identified. In this study, we identified the immunomodulator from C. elaphus
한소엽, 전길자, 김길현
core   +1 more source

Studies of the thermotropic phase behavior of phosphatidylcholines containing 2-alkyl substituted fatty acyl chains: a new class of phosphatidylcholines forming inverted nonlamellar phases [PDF]

, 1994
We have synthesized a number of 1,2-diacyl phosphatidylcholines with hydrophobic substituents adjacent to the carbonyl group of the fatty acyl chain and studied their thermotropic phase behavior by differential scanning calorimetry, 31P-nuclear magnetic ...
Gruner, S.M., Harper, P.E., Turner, D.C., Lewis, R.N., McElhaney, R.N.   +4 more
core   +1 more source

Association Study between Biomarkers of Metabolites and Their Relevance Genes for Hypertension in Korean Adults

Korean Journal of Clinical Laboratory Science
Metabolites are intermediates and the end-products of biological pathways, and are closely associated with biochemical activity and clinical characteristics, making them useful indicators of disease.
Jaemee JUNG, Hyeyoung LEE, Dahyun HWANG
doaj   +1 more source

Mass Spectrometric Analyses of Phosphatidylcholines in Alkali-Exposed Corneal Tissue

, 2012
Alkali exposure dramatically changes the phosphatidylcholines (PCs) of the cornea. Findings are consistent with penetration and hydrolysis as stochastic contributors to changes in PCs due exposure to alkali for a finite duration and ...
Lam, Byron L, Coggin, Andrew D, Crane, Ashley M, Bhattacharya, Sanjoy K, Hua, Hong-Uyen, Gugiu, Bogdan G   +5 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Oxidized phosphatidylcholines are produced in renal ischemia reperfusion injury. [PDF]

PLoS ONE, 2018
The aim of this study was to determine the individual oxidized phosphatidylcholine (OxPC) molecules generated during renal ischemia/ reperfusion (I/R) injury.Kidney ischemia was induced in male Sprague-Dawley rats by clamping the left renal pedicle for ...
Zahra Solati, Andrea L Edel, Yue Shang, Karmin O, Amir Ravandi   +4 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source