Metabolites are intermediates and the end-products of biological pathways, and are closely associated with biochemical activity and clinical characteristics, making them useful indicators of disease.
Jaemee JUNG, Hyeyoung LEE, Dahyun HWANG
doaj +1 more source
Effect of phospholipids and bile acids on cholesterol nucleation time and vesicular/micellar cholesterol in gallbladder bile of patients with cholesterol stones [PDF]
Supersaturation and rapid nucleation of cholesterol in bile are of key importance in the pathogenesis of cholesterol gallstones. While the effects of bile acids and phospholipids on cholesterol saturation of bile have been extensively studied, their ...
Huber, P. +4 more
core
Remotely Controlled Diffusion from Magnetic Liposome Microgels [PDF]
The reversible, temperature-dependent change in the permeability of a phospholipid bilayer has been used for controlling the diffusion rate of encapsulated molecular payload from liposomes.
Dohnal, Jiří +4 more
core +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
A Simulation Study on Multicomponent Lipid Bilayer
Simulation of a multicomponent lipid bilayer having a fixed percentage of cholesterol is done to study phase transition leading to domain formation.
Anderson +28 more
core +1 more source
Phosphatidylcholine transfer protein from bovine liver contains highly unsaturated phosphatidylcholine species [PDF]
The phosphatidylcholine transfer protein (PC‐TP) from bovine liver contains one molecule of non‐covalently bound PC. In order to gain more insight into the physiological function of PC‐TP, PC was extracted from bovine liver PC‐TP and its molecular species composition identified by fast atom bombardment mass spectrometry.
Geijtenbeek, T. B. +3 more
openaire +2 more sources
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Current perspectives for metabolomics and lipidomics in dyslipidemia of acne vulgaris: a mini review
Acne vulgaris (AV) is a common inflammatory disorder involving the pilosebaceous unit. Many studies have reported that people with AV have higher levels of total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol (LDL-c ...
Liang Wu +6 more
doaj +1 more source
Oxidized phosphatidylcholines are produced in renal ischemia reperfusion injury. [PDF]
The aim of this study was to determine the individual oxidized phosphatidylcholine (OxPC) molecules generated during renal ischemia/ reperfusion (I/R) injury.Kidney ischemia was induced in male Sprague-Dawley rats by clamping the left renal pedicle for ...
Zahra Solati +4 more
doaj +1 more source
Miscibility of Phosphatidylcholines in Bilayers: Effect of Acyl Chain Unsaturation
The miscibility of phospholipids in a hydrated bilayer is an issue of fundamental importance for understanding the organization of biological membranes. Despite research on lipid miscibility, its molecular basis remains poorly understood.
Agata Żak +3 more
doaj +1 more source

