Results 41 to 50 of about 19,173 (307)

Current perspectives for metabolomics and lipidomics in dyslipidemia of acne vulgaris: a mini review

Frontiers in Medicine
Acne vulgaris (AV) is a common inflammatory disorder involving the pilosebaceous unit. Many studies have reported that people with AV have higher levels of total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol (LDL-c ...
Liang Wu, Sheng-Cai Zhu, Yang He, Yun-Xia Zhu, Xiao-Liang Ou-Yang, Deng Zhang, Chun-Ming Li   +6 more
doaj   +1 more source

Preferable stimulation of PON1 arylesterase activity by phosphatidylcholines with unsaturated acyl chains or oxidized acyl chains at sn-2 position [PDF]

, 2006
To examine the effect of phospholipids on PON1 activities, purified PON1 was exposed to phospholipids prior to the determination of arylesterase and paraoxonase activities. Phosphatidylcholines with saturated acyl chains (C10–C16) showed a stimulation of
Sok, Dai-Eun, Nguyen, Su Duy
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Determination of phosphatidylcholine and disaturated phosphatidylcholine content in lung surfactant by high performance liquid chromatography.

Journal of Lipid Research, 1989
A rapid isocratic method for determining the total phosphatidylcholine and disaturated phosphatidylcholine levels in lung surfactant preparations by high performance liquid chromatography (HPLC) is described.
J Scarim, H Ghanbari, V Taylor, G Menon
doaj   +1 more source

Effects of vasopressin on the synthesis of phosphatidylethanolamines and phosphatidylcholines by isolated rat hepatocytes [PDF]

, 1987
The effect of vasopressin on the biosynthesis of phosphatidylcholines and phosphatidylethanolamines was investigated in freshly isolated rat hepatocytes in suspension.
Golde, L.M.G. van, Schuurmans, E.A.J.M., Tijburg, L.B.M., Geelen, M.J.H.   +3 more
core   +1 more source

Programming Nanoscale Reaction Environments via Peptide Localization for Gold Nanoparticle Growth in Liposomal Nanoreactors

Advanced Functional Materials, EarlyView.
The liposome nanoreactor method enables uniform metal nanoparticle synthesis using the interior as a reaction environment. We demonstrate that peptide sequences and lipid compositions act as a functional molecular switch to control reaction environments in liposome nanoreactors.
Yuya Abe, Joseph Fox, Zabeada Aslam, Kevin Critchley, Stephen D. Evans, Mina Okochi, Masayoshi Tanaka   +6 more
wiley   +1 more source

Role of Lipidomics in Respiratory Tract Infections: A Systematic Review of Emerging Evidence

Microorganisms
Lower respiratory tract infections (LRTIs) remain a major cause of global morbidity and mortality, yet accurate pathogen identification and risk stratification continue to pose clinical challenges.
Vasiliki E. Georgakopoulou, Konstantinos Dodos, Vassiliki C. Pitiriga   +2 more
doaj   +1 more source

The human plasma-metabolome: Reference values in 800 French healthy volunteers; impact of cholesterol, gender and age.

PLoS ONE, 2017
Metabolomic approaches are increasingly used to identify new disease biomarkers, yet normal values of many plasma metabolites remain poorly defined. The aim of this study was to define the "normal" metabolome in healthy volunteers. We included 800 French
Séverine Trabado, Abdallah Al-Salameh, Vincent Croixmarie, Perrine Masson, Emmanuelle Corruble, Bruno Fève, Romain Colle, Laurent Ripoll, Bernard Walther, Claire Boursier-Neyret, Erwan Werner, Laurent Becquemont, Philippe Chanson   +12 more
doaj   +1 more source

Reliability of Serum Metabolites over a Two-Year Period: A Targeted Metabolomic Approach in Fasting and Non-Fasting Samples from EPIC.

PLoS ONE, 2015
ObjectiveAlthough metabolic profiles have been associated with chronic disease risk, lack of temporal stability of metabolite levels could limit their use in epidemiological investigations.
Marion Carayol, Idlir Licaj, David Achaintre, Carlotta Sacerdote, Paolo Vineis, Timothy J Key, N Charlotte Onland Moret, Augustin Scalbert, Sabina Rinaldi, Pietro Ferrari   +9 more
doaj   +1 more source

Functional Differentiation of Type II and Type I Collagen Articular Models in Synovial Fluid Film Formation and Recombinant Equine Lubricin Retention

Advanced Functional Materials, EarlyView.
Collagen II coatings support the formation of synovial fluid nanofilms, while collagen I coatings do not. Both bind recombinant equine lubricin similarly. These findings may help explain articular cartilage surface joint dysfunction, inform biomaterial design for synovial joint repair, and expand on lubricin‐based osteoarthritis therapies.
Diego R. Jaramillo Pinto, Nicolas L. Mendoza, Syeda Tajin Ahmed, Yidan Wen, Lenka Vitkova, Spencer M. Witt, Kaleb A. Cutter, Ummay Honey, Matthew J. Paszek, Heidi L. Reesink, Lawrence J. Bonassar, Kevin De France, Roberto C. Andresen Eguiluz   +12 more
wiley   +1 more source