Results 41 to 50 of about 15,382 (263)

Increased dietary methionine, lysine and histidine supply modulated the heat stress-induced metabolic remodeling of dairy cows

Frontiers in Animal Science
Increasing dietary Met, Lys, and His supply without increasing the dietary protein content was reported to partially alleviate the productive and physiological impact of heat stress. Nevertheless, the metabolic pathways involved are yet to be identified.
Ezequiel Jorge-Smeding, Ezequiel Jorge-Smeding, Alexis Ruiz-González, Alexis Ruiz-González, Yue Hei Leung, Ana Inés Trujillo, Ana Laura Astessiano, Daniel R. Ouellet, Hélène Lapierre, Daniel E. Rico, Ákos Kenéz   +10 more
doaj   +1 more source

Engineering Nanoplatforms for Alzheimer's Disease Detection via Biomolecular Corona Proteomic and Lipidomic Profiling

Advanced Healthcare Materials, EarlyView.
Engineered nanoparticles capture disease‐specific biomolecular coronas that uncover hidden molecular features of Alzheimer's disease. Combined proteomic and lipidomic analyses reveal a characteristic shift in ribosomal machinery and energy metabolism, generating a multiomic fingerprint that supports accurate disease detection and opens new ...
Antonietta Greco, Roberto Baretta, Andrea Di Fonzo, Andrea Armirotti, Stefano Cinti, Mara Mirasoli, Marco Frasconi, Claudia Corbo   +7 more
wiley   +1 more source

Advent of Novel Phosphatidylcholine-Associated Nonsteroidal Anti-Inflammatory Drugs with Improved Gastrointestinal Safety

Gut and Liver, 2013
The mucosa of the gastrointestinal (GI) tract exhibits hydrophobic, nonwettable properties that protect the underlying epithelium from gastric acid and other luminal toxins.
doaj   +1 more source

Use of 31PNMR spectroscopy to follow the time course of phosphatidylcholine chemical synthesis.

Journal of Lipid Research, 1985
31PNMR spectroscopy is shown to be useful for studying the chemical synthesis of phosphatidylcholine from phosphatidic acid and choline. Sharp, well-resolved resonances were obtained by chelating multivalent cations, thereby enabling quantitation of ...
P R Meers, G W Feigenson
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Exploratory analysis of epilepsy biomarkers using untargeted metabolomics across multiple cohorts

Frontiers in Neurology
IntroductionEpilepsy is a common central nervous system disorder characterized by abnormal brain electrical activity. Diagnosing epilepsy can be challenging, as it has various causes and different clinical manifestations.
Kaisa T. Oja, Kaisa T. Oja, Mihkel Ilisson, Mihkel Ilisson, Karit Reinson, Karit Reinson, Kai Muru, Kai Muru, Tiia Reimand, Tiia Reimand, Hedi Peterson, Dmytro Fishman, Dmytro Fishman, Toomas Haller, Jaanika Kronberg, Estonian Biobank Research Team, Monica H. Wojcik, Monica H. Wojcik, Monica H. Wojcik, Adam D. Kennedy, Laura Sommerville, Gregory Michelotti, Anne O’Donnell-Luria, Anne O’Donnell-Luria, Eve Õiglane-Shlik, Eve Õiglane-Shlik, Sander Pajusalu, Sander Pajusalu, Katrin Õunap, Katrin Õunap   +29 more
doaj   +1 more source

Viscosity of phosphatidylcholine (lecithin)

Journal of Pharmacy and Pharmacology, 1966
AbstractThe viscosities of egg lecithin dispersed in water have been measured by means of a Couette viscometer. The more concentrated dispersions are thixotropic, but below 1·8% w/w of lecithin the sols become Newtonian. From the extrapolated ratio of specific viscosity to volume fraction, the dispersed particles are considered to be of an elongated ...
J H, Perrin, L, Saunders
openaire   +2 more sources

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Negotiating in a Foreign Land: Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles

Advanced Materials Interfaces, EarlyView.
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley   +1 more source

Impaired response of biliary lipid secretion to a lithogenic diet in phosphatidylcholine transfer protein-deficient mice

Journal of Lipid Research, 2005
Phosphatidylcholine transfer protein (PC-TP) is a cytosolic lipid transfer protein that is highly expressed in liver and catalyzes intermembrane transfer of phosphatidylcholines in vitro.
Michele K. Wu, Hideyuki Hyogo, Suresh K. Yadav, Phyllis M. Novikoff, David E. Cohen   +4 more
doaj   +1 more source