Oxidized Phosphatidylcholines Facilitate Phospholipid Flip-Flop in Liposomes [PDF]
Lipid asymmetry is a ubiquitous property of the lipid bilayers in cellular membranes and its maintenance and loss play important roles in cell physiology, such as blood coagulation and apoptosis.
Lukasz Cwiklik +11 more
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Synthesis and Biological Evaluation of Novel Phosphatidylcholine Analogues Containing Monoterpene Acids as Potent Antiproliferative Agents. [PDF]
The synthesis of novel phosphatidylcholines with geranic and citronellic acids in sn-1 and sn-2 positions is described. The structured phospholipids were obtained in high yields (59-87%) and evaluated in vitro for their cytotoxic activity against several
Anna Gliszczyńska +5 more
doaj +1 more source
The effect of fasting and refeeding on the composition and synthesis of triacylglycerols, phosphatidylcholines, and phosphatidylethanolamines in rat liver [PDF]
Refeeding a high-sucrose, fat-free diet to fasted rats caused drastic alterations in the fatty acid composition of hepatic diacylglycerols, triacylglycerols, and phosphatidylcholines.
Klein, W. +2 more
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(1) Background: This work aims to investigate the metabolomic changes in PIGinH11 pigs and investigate differential compounds as potential therapeutic targets for metabolic diseases.
Jianping Xu +6 more
doaj +1 more source
Phase stability of phosphatidylcholines in dimethylsulfoxide solutions [PDF]
The temperature dependence of the phase stability of dispersions of dimyristoyl, dipalmitoyl, and distearoyl derivatives of phosphatidylcholines in excess aqueous dimethylsulfoxide has been examined by differential scanning calorimetry and synchrotron x ...
Quinn, P.J., Yu, Z.W.
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Lysophosphatidylcholines and phosphatidylcholines as biomarkers for stroke recovery
Stroke is a serious global public health issue, associated with severe disability and high mortality rates. Its early detection is challenging, and no effective biomarkers are available.
Meiling Huang +8 more
doaj +1 more source
Analysis of the bilayer phase transition temperatures of phosphatidylcholines with mixed chains [PDF]
The analysis of the chain-length dependence of the chain-melting transition temperatures of bilayers composed of lipids with identical chains (Marsh, D. 1991. Biochim. Biophys. Acta. 1062: 1–6) is extended to include lipids with chains of unequal length.
Marsh, D., Marsh, Derek
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Effect of phospholipids and bile acids on cholesterol nucleation time and vesicular/micellar cholesterol in gallbladder bile of patients with cholesterol stones [PDF]
Supersaturation and rapid nucleation of cholesterol in bile are of key importance in the pathogenesis of cholesterol gallstones. While the effects of bile acids and phospholipids on cholesterol saturation of bile have been extensively studied, their ...
Paumgartner, Gustav +4 more
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Reduced abundance of phosphatidylcholines (PC) in high risk and RRMM, measured by targeted lipidomics.
Markus R. Wenk (136744) +11 more
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An efficient synthesis of phosphatidylcholines.
This article deals with two of the major steps involved in phospholipid synthesis: the preparation of the optically pure precursors, sn-glycero-3-phosphocholine (GPC) and -ethanolamine, from a convenient lipid source such as egg yolk, and acylation of ...
A Singh
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