Results 11 to 20 of about 80,395 (343)

Lysophosphatidylcholines and phosphatidylcholines as biomarkers for stroke recovery

Frontiers in Neurology, 2022
Stroke is a serious global public health issue, associated with severe disability and high mortality rates. Its early detection is challenging, and no effective biomarkers are available.
Meiling Huang, Shaohang Xu, Mingchao Zhou, Jiao Luo, Fubing Zha, Linlin Shan, Qingqing Yang, Baojin Zhou, Yulong Wang   +8 more
doaj   +2 more sources

Structural library and visualization of endogenously oxidized phosphatidylcholines using mass spectrometry-based techniques

Nature Communications, 2021
Oxidized phosphatidylcholines (oxPCs) are a structurally diverse class of lipids associated with various diseases. Here, the authors use mass spectrometry to construct a spectral library of 465 oxPCs and subsequently profile oxPCs formed during ...
Yuta Matsuoka, Masatomo Takahashi, Yuki Sugiura, Yoshihiro Izumi, Kazuhiro Nishiyama, Motohiro Nishida, Makoto Suematsu, Takeshi Bamba, Ken-ichi Yamada   +8 more
doaj   +2 more sources

Phase behaviour of dehydrated phosphatidylcholines [PDF]

Journal of Thermal Analysis and Calorimetry, 2016
Dehydrated DLPC, DMPC, DPPC and DSPC have been characterised at temperatures below the diacyl carbon chain-melting transition (Tm), using DSC. For the first time, the existence of pre-Tm transition processes, which are, usually, only observed in the ...
AS Ulrich, AV Popova, AV Popova, AV Popova, B Stark, B Wang, Babur Z. Chowdhry, BB Sauer, BB Sauer, D Chapman, D Chapman, D Chapman, D Marsh, JH Crowe, Milan D. Antonijević, R Koynova, RR Keuleers, S Leekumjorn, Samuel K. Owusu-Ware, SH El-Taweel, Stephen A. Leharne, UP Fringeli, Z Qui   +22 more
core   +2 more sources

MARC1 variant rs2642438 increases hepatic phosphatidylcholines and decreases severity of non-alcoholic fatty liver disease in humans.

Journal of Hepatology, 2020
MARC1 variant rs2642438 increases hepatic phosphatidylcholines and decreases severity of non-alcoholic fatty liver disease in ...
P. Luukkonen, A. Juuti, H. Sammalkorpi, A. Penttilä, M. Orešič, T. Hyötyläinen, J. Arola, M. Orho-Melander, H. Yki-Järvinen   +8 more
semanticscholar   +1 more source

Fasting increases 18:2-containing phosphatidylcholines to complement the decrease in 22:6-containing phosphatidylcholines in mouse skeletal muscle.

PLoS ONE, 2021
Fasting stimulates catabolic reactions in skeletal muscle to survive nutrient deprivation. Cellular phospholipids have large structural diversity due to various polar-heads and acyl-chains that affect many cellular functions. Skeletal muscle phospholipid
Nanami Senoo, Takumi Akahori, Hiyori Ichida, Noriyuki Miyoshi, Akihito Morita, Takao Shimizu, Hideo Shindou, Shinji Miura   +7 more
doaj   +1 more source

Elevated Free Phosphatidylcholine Levels in Cerebrospinal Fluid Distinguish Bacterial from Viral CNS Infections

Cells, 2021
The identification of CSF biomarkers for bacterial meningitis can potentially improve diagnosis and understanding of pathogenesis, and the differentiation from viral CNS infections is of particular clinical importance.
Amani Al-Mekhlafi, Kurt-Wolfram Sühs, Sven Schuchardt, Maike Kuhn, Kirsten Müller-Vahl, Corinna Trebst, Thomas Skripuletz, Frank Klawonn, Martin Stangel, Frank Pessler   +9 more
doaj   +1 more source

Assessment of metabolomic and proteomic biomarkers in detection and prognosis of progression of renal function in chronic kidney disease [PDF]

, 2014
Chronic kidney disease (CKD) is part of a number of systemic and renal diseases and may reach epidemic proportions over the next decade. Efforts have been made to improve diagnosis and management of CKD.
Argilés, Àngel, Dakna, Mohammed, Delles, Christian, Duranton, Flore, Gayrard, Nathalie, Husi, Holger, Klein, Julie, Koeck, Thomas, Lundin, Ulrika, Mischak, Harald, Mullen, William, Nkuipou-Kenfack, Esther, Weinberger, Klaus M., Zürbig, Petra   +13 more
core   +9 more sources

Differential determination of phospholipase A2 and PAF-acetylhydrolase in biological fluids using fluorescent substrates

Journal of Lipid Research, 1999
The purpose of the present study was the development and evaluation of a fluorimetric method for the screening and differential determination of phospholipase A2 and PAF-acetylhydrolase in bronchoalveolar lavage (BAL) fluid and serum.
Eirini I. Kitsiouli, George Nakos, Marilena E. Lekka   +2 more
doaj   +1 more source

Discovery of Sexual Dimorphisms in Metabolic and Genetic Biomarkers [PDF]

, 2007
Metabolomic profiling and the integration of whole-genome genetic association data has proven to be a powerful tool to comprehensively explore gene regulatory networks and to investigate the effects of genetic variation at the molecular level.
Mittelstrass, Kirstin, Ried, Janina S., Yu, Zhonghao, Krumsiek, Jan, Gieger, Christian, Prehn, Cornelia, Roemisch-Margl, Werner, Polonikov, Alexey, Peters, Annette, Theis, Fabian J., Meitinger, Thomas, Kronenberg, Florian, Weidinger, Stephan, Wichmann, Heinz-Erich, Suhre, Karsten, Wang-Sattler, Rui, Adamski, Jerzy, Illig, Thomas   +17 more
core   +2 more sources

Barbiturate Interaction with Phosphatidylcholine [PDF]

Proceedings of the National Academy of Sciences, 1972
A hydrogen-bonding interaction between phenobarbital or pentobarbital with phosphatidylcholine in chloroform is indicated by the effects of added phosphatidylcholine on the infrared and proton magnetic resonance spectra of these barbiturates. The nitrogenbound proton of the barbiturate and the orthophosphate moiety of the phosphatidylcholine molecule ...
R F, Novak, T J, Swift
openaire   +2 more sources