Results 61 to 70 of about 80,395 (343)

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Use of 31PNMR spectroscopy to follow the time course of phosphatidylcholine chemical synthesis.

Journal of Lipid Research, 1985
31PNMR spectroscopy is shown to be useful for studying the chemical synthesis of phosphatidylcholine from phosphatidic acid and choline. Sharp, well-resolved resonances were obtained by chelating multivalent cations, thereby enabling quantitation of ...
P R Meers, G W Feigenson
doaj   +1 more source

Characterization of acyl chain position in unsaturated phosphatidylcholines using differential mobility-mass spectrometry[S]

Journal of Lipid Research, 2014
Glycerophospholipids (GPs) that differ in the relative position of the two fatty acyl chains on the glycerol backbone (i.e., sn-positional isomers) can have distinct physicochemical properties.
A. Maccarone, J. Duldig, Todd W. Mitchell, S. Blanksby, E. Duchoslav, J. Larry Campbell   +5 more
semanticscholar   +1 more source

Discrimination of papillary thyroid cancer from non-cancerous thyroid tissue based on lipid profiling by mass spectrometry imaging [PDF]

, 2018
Introduction: The distinction of papillary thyroid carcinomas from benign thyroid lesions has important implication for clinical management. Classification based on histopathological features can be supported by molecular biomarkers, including lipidomic ...
Bednarczyk, K, Chekan, M, Clench, Malcolm, Cole, Laura, Jarząb, B, Maksymiak, M, Oczko-Wojciechowska, M, Pietrowska, M, Polańska, J, Widlak, P, Wojakowska, A   +10 more
core   +2 more sources

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Increased dietary methionine, lysine and histidine supply modulated the heat stress-induced metabolic remodeling of dairy cows

Frontiers in Animal Science
Increasing dietary Met, Lys, and His supply without increasing the dietary protein content was reported to partially alleviate the productive and physiological impact of heat stress. Nevertheless, the metabolic pathways involved are yet to be identified.
Ezequiel Jorge-Smeding, Ezequiel Jorge-Smeding, Alexis Ruiz-González, Alexis Ruiz-González, Yue Hei Leung, Ana Inés Trujillo, Ana Laura Astessiano, Daniel R. Ouellet, Hélène Lapierre, Daniel E. Rico, Ákos Kenéz   +10 more
doaj   +1 more source

A generic model for lipid monolayers, bilayers, and membranes

, 2006
We describe a simple coarse-grained model which is suited to study lipid layers and their phase transitions. Lipids are modeled by short semiflexible chains of beads with a solvophilic head and a solvophobic tail component.
Beate West, Cooke, de Vries, Dominik Düchs, Düchs, Farago, Frenkel, Friederike Schmid, Gennis, Goetz, Heffelfinger, Kaganer, Koynova, Kranenburg, Lenz, Lenz, Noguchi, Olaf Lenz, Shillcock, Smit, Stadler, Stadler, Uhlherr   +22 more
core   +1 more source

Anti-malarial drug artesunate restores metabolic changes in experimental allergic asthma [PDF]

, 2016
The anti-malarial drug artesunate possesses anti-inflammatory and anti-oxidative actions in experimental asthma, comparable to corticosteroid. We hypothesized that artesunate may modulate disease-relevant metabolic alterations in allergic asthma.
Cheng, Chang, Ho, Wanxing Eugene, Huang, Shao-Min, Ong, Choon Nam, Peh, Hong Yong, Tannenbaum, Steven R, Wong, W. S. Fred, Xu, Fengguo, Xu, Yong-Jiang   +8 more
core   +1 more source

Mass spectrometry images acylcarnitines, phosphatidylcholines, and sphingomyelin in MDA-MB-231 breast tumor models[S]

Journal of Lipid Research, 2013
The lipid compositions of different breast tumor microenvironments are largely unknown due to limitations in lipid imaging techniques. Imaging lipid distributions would enhance our understanding of processes occurring inside growing tumors, such as ...
K. Chughtai, Lu Jiang, T. Greenwood, K. Glunde, R. Heeren   +4 more
semanticscholar   +1 more source