Results 81 to 90 of about 80,395 (343)

Viscosity of phosphatidylcholine (lecithin)

open access: yesJournal of Pharmacy and Pharmacology, 1966
AbstractThe viscosities of egg lecithin dispersed in water have been measured by means of a Couette viscometer. The more concentrated dispersions are thixotropic, but below 1·8% w/w of lecithin the sols become Newtonian. From the extrapolated ratio of specific viscosity to volume fraction, the dispersed particles are considered to be of an elongated ...
J H, Perrin, L, Saunders
openaire   +2 more sources

Cell Cycle Control of Nuclear Metabolism Couples Phosphatidylinositol Signaling to Histone Methylation

open access: yesAdvanced Science, EarlyView.
Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater   +13 more
wiley   +1 more source

Impaired response of biliary lipid secretion to a lithogenic diet in phosphatidylcholine transfer protein-deficient mice

open access: yesJournal of Lipid Research, 2005
Phosphatidylcholine transfer protein (PC-TP) is a cytosolic lipid transfer protein that is highly expressed in liver and catalyzes intermembrane transfer of phosphatidylcholines in vitro.
Michele K. Wu   +4 more
doaj   +1 more source

Phospholipid Species in Newborn and 4 Month Old Infants after Consumption of Different Formulas or Breast Milk. [PDF]

open access: yesPLoS ONE, 2016
INTRODUCTION:Arachidonic acid (AA) and docosahexaenoic acid (DHA) are important long-chain polyunsaturated fatty acids for neuronal and cognitive development and are ingredients of infant formulae that are recommended but there is no evidence based ...
Olaf Uhl   +4 more
doaj   +1 more source

Metabolomic profiling predicts outcome of rituximab therapy in rheumatoid arthritis. [PDF]

open access: yes, 2016
ObjectiveTo determine whether characterisation of patients' metabolic profiles, utilising nuclear magnetic resonance (NMR) and mass spectrometry (MS), could predict response to rituximab therapy. 23 patients with active, seropositive rheumatoid arthritis
Boyle, David   +6 more
core   +2 more sources

Phosphatidylcholine: cholesterol phase diagrams.

open access: yesBiophysical journal, 2010
Two mono-cis-unsaturated phosphatidylcholine (PC) lipid molecules, having very different gel-liquid crystalline phase transition temperatures as a consequence of the relative positions of the double bond, exhibit PC:cholesterol phase diagrams that are very similar to each other and to that obtained previously for a fully saturated PC:cholesterol ...
Thewalt, Jenifer L., Bloom, Myer
openaire   +2 more sources

A simplified procedure for semi-targeted lipidomic analysis of oxidized phosphatidylcholines induced by UVA irradiation

open access: yesJournal of Lipid Research, 2012
Oxidized phospholipids (OxPLs) are increasingly recognized as signaling mediators that are not only markers of oxidative stress but are also “makers” of pathology relevant to disease pathogenesis. Understanding the biological role of individual molecular
F. Gruber   +4 more
semanticscholar   +1 more source

Targeting the PGRN‐BMP Lysosomal Axis With NPs@PGRN Reverses Immunometabolic Dysfunction in Chronic Septic Arthritis

open access: yesAdvanced Science, EarlyView.
Chronic septic arthritis involves intracellular bacterial persistence and lipid‐immune crosstalk via the PGRN‐BMP lysosomal axis. A dual‐targeting nanoparticle system (NPs@PGRN) restores lysosomal bactericidal function, reduces bacterial burden, and reprograms macrophage immunity, offering a novel therapeutic strategy. ABSTRACT Chronic septic arthritis,
Congsun Li   +12 more
wiley   +1 more source

Serum metabolite profiling reveals metabolic characteristics of sepsis patients using LC/MS-based metabolic profiles: a cross-sectional study

open access: yesBMC Medical Genomics, 2023
Background Individuals with sepsis exhibited a higher likelihood of benefiting from early initiation of specialized treatment to enhance the prognosis of the condition. The objective of this study is to identify potential biomarkers of sepsis by means of
Jinliang Peng   +3 more
doaj   +1 more source

Platelet interaction with bioactive lipids formed by mild oxidation of low-density lipoprotein [PDF]

open access: yes, 2006
Oxidation of low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that play a crucial role in cardiovascular and inflammatory diseases.
Siess, Wolfgang
core   +1 more source

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