Results 31 to 40 of about 33,560 (288)

Effect of phospholipids and bile acids on cholesterol nucleation time and vesicular/micellar cholesterol in gallbladder bile of patients with cholesterol stones [PDF]

, 1993
Supersaturation and rapid nucleation of cholesterol in bile are of key importance in the pathogenesis of cholesterol gallstones. While the effects of bile acids and phospholipids on cholesterol saturation of bile have been extensively studied, their ...
Huber, P., Jüngst, Dieter, Lang, Thomas, Lange, V., Paumgartner, Gustav   +4 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Association Study between Biomarkers of Metabolites and Their Relevance Genes for Hypertension in Korean Adults

Korean Journal of Clinical Laboratory Science
Metabolites are intermediates and the end-products of biological pathways, and are closely associated with biochemical activity and clinical characteristics, making them useful indicators of disease.
Jaemee JUNG, Hyeyoung LEE, Dahyun HWANG
doaj   +1 more source

Oxidized phosphatidylcholines are produced in renal ischemia reperfusion injury. [PDF]

PLoS ONE, 2018
The aim of this study was to determine the individual oxidized phosphatidylcholine (OxPC) molecules generated during renal ischemia/ reperfusion (I/R) injury.Kidney ischemia was induced in male Sprague-Dawley rats by clamping the left renal pedicle for ...
Zahra Solati, Andrea L Edel, Yue Shang, Karmin O, Amir Ravandi   +4 more
doaj   +1 more source

Rigid Chiral Membranes [PDF]

, 1992
Statistical ensembles of flexible two-dimensional fluid membranes arise naturally in the description of many physical systems. Typically one encounters such systems in a regime of low tension but high stiffness against bending, which is just the opposite
A. Polyakov, A. Singh, B. Thomas, D. Förster, D. R. Nelson, D. R. Nelson, F. David, F. David, G. Hinshaw, G. Hinshaw, H. Kleinert, I. Dahl, J. Georger, L. Peliti, L. Peliti, Ou-Yang Zhong-Can, P. Canham, P. G. de Gennes, P. Yager, Philip Nelson, R. Treanor, S. Dierker, S. Langer, T. C. Lubensky, Thomas Powers, W. Heckl, W. Helfrich, W. Helfrich, W. Helfrich, W. Helfrich, X. Qiu   +30 more
core   +4 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Miscibility of Phosphatidylcholines in Bilayers: Effect of Acyl Chain Unsaturation

Membranes, 2023
The miscibility of phospholipids in a hydrated bilayer is an issue of fundamental importance for understanding the organization of biological membranes. Despite research on lipid miscibility, its molecular basis remains poorly understood.
Agata Żak, Natan Rajtar, Waldemar Kulig, Mariusz Kepczynski   +3 more
doaj   +1 more source

A Simulation Study on Multicomponent Lipid Bilayer

, 2005
Simulation of a multicomponent lipid bilayer having a fixed percentage of cholesterol is done to study phase transition leading to domain formation.
Anderson, Anderson, Banerjee, Banerjee, Ben-Shaul, Bloom, Brown, Brown, Brown, de Miguel, Doniach, Ermoshkin, Evans, Ferrenberg, Harrison, Jacobson, Jayashree Saha, Lee, May, Mouritsen, Nielsen, Nielsen, Radhakrishnan, Sabra, Scherfeld, Simons, Simons, Srilekha Banerjee, Zhang   +28 more
core   +1 more source

Metabolomic profiling predicts outcome of rituximab therapy in rheumatoid arthritis. [PDF]

, 2016
ObjectiveTo determine whether characterisation of patients' metabolic profiles, utilising nuclear magnetic resonance (NMR) and mass spectrometry (MS), could predict response to rituximab therapy. 23 patients with active, seropositive rheumatoid arthritis
Boyle, David, Guma, Monica, Kavanaugh, Arthur, Lodi, Alessia, Sweeney, Shannon R, Tiziani, Stefano, Wang, Bo   +6 more
core   +2 more sources

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source