Results 61 to 70 of about 33,560 (288)

Use of 31PNMR spectroscopy to follow the time course of phosphatidylcholine chemical synthesis.

Journal of Lipid Research, 1985
31PNMR spectroscopy is shown to be useful for studying the chemical synthesis of phosphatidylcholine from phosphatidic acid and choline. Sharp, well-resolved resonances were obtained by chelating multivalent cations, thereby enabling quantitation of ...
P R Meers, G W Feigenson
doaj   +1 more source

Phase behaviour of dehydrated phosphatidylcholines [PDF]

, 2016
Dehydrated DLPC, DMPC, DPPC and DSPC have been characterised at temperatures below the diacyl carbon chain-melting transition (Tm), using DSC. For the first time, the existence of pre-Tm transition processes, which are, usually, only observed in the ...
AS Ulrich, AV Popova, AV Popova, AV Popova, B Stark, B Wang, Babur Z. Chowdhry, BB Sauer, BB Sauer, D Chapman, D Chapman, D Chapman, D Marsh, JH Crowe, Milan D. Antonijević, R Koynova, RR Keuleers, S Leekumjorn, Samuel K. Owusu-Ware, SH El-Taweel, Stephen A. Leharne, UP Fringeli, Z Qui   +22 more
core   +1 more source

Preliminary Study of a Ninj1‐Loaded Bimodal Ultrasound/NIR Fluorescence Targeted Molecular Probe for Diagnosing Early‐Stage Inflammation in Coronary Microvascular Dysfunction

Advanced Healthcare Materials, EarlyView.
Coronary microvascular dysfunction (CMD) targeting remains a challenge for precise diagnosis. This work presents a dual‐modal nanoprobe (T‐IR780‐NBs) that combines ultrasound contrast with near‐infrared fluorescence. This technology utilizes proteomics‐derived antibodies that specifically localize to inflamed and injured cardiac tissue, enabling ...
Xiaohui Xu, Lina Guan, Baihetiya Tayier, Chen Yuan, Shangke Chen, Qi Shi, Yuming Mu   +6 more
wiley   +1 more source

Exploratory analysis of epilepsy biomarkers using untargeted metabolomics across multiple cohorts

Frontiers in Neurology
IntroductionEpilepsy is a common central nervous system disorder characterized by abnormal brain electrical activity. Diagnosing epilepsy can be challenging, as it has various causes and different clinical manifestations.
Kaisa T. Oja, Kaisa T. Oja, Mihkel Ilisson, Mihkel Ilisson, Karit Reinson, Karit Reinson, Kai Muru, Kai Muru, Tiia Reimand, Tiia Reimand, Hedi Peterson, Dmytro Fishman, Dmytro Fishman, Toomas Haller, Jaanika Kronberg, Estonian Biobank Research Team, Monica H. Wojcik, Monica H. Wojcik, Monica H. Wojcik, Adam D. Kennedy, Laura Sommerville, Gregory Michelotti, Anne O’Donnell-Luria, Anne O’Donnell-Luria, Eve Õiglane-Shlik, Eve Õiglane-Shlik, Sander Pajusalu, Sander Pajusalu, Katrin Õunap, Katrin Õunap   +29 more
doaj   +1 more source

Dehydration of solute-lipid systems: Hydration forces analysis [PDF]

, 2004
Sorption isotherms were obtained for a range of lipid/sugar/water mixtures. These were analysed using a simple hydration forces formalism. The results demonstrate that this simple analysis can be used to estimate dehydration parameters for these ...
Bryant, G, Koster, K
core   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Sets of coregulated serum lipids are associated with Alzheimer's disease pathophysiology [PDF]

, 2019
Introduction: Comorbidity with metabolic diseases indicates that lipid metabolism plays a role in the etiology of Alzheimer's disease (AD). Comprehensive lipidomic analysis can provide new insights into the altered lipid metabolism in AD.
Arnold, Matthias, Baillie, Rebecca, Barupal, Dinesh Kumar, Consortium, Alzheimer Disease Metabolomics, Fan, Sili, Fiehn, Oliver, Initiative, Alzheimer's Disease Neuroimaging, Kaddurah‐Daouk, Rima, Meikle, Peter J, Nho, Kwangsik, Saykin, Andrew J   +10 more
core   +2 more sources

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Impaired response of biliary lipid secretion to a lithogenic diet in phosphatidylcholine transfer protein-deficient mice

Journal of Lipid Research, 2005
Phosphatidylcholine transfer protein (PC-TP) is a cytosolic lipid transfer protein that is highly expressed in liver and catalyzes intermembrane transfer of phosphatidylcholines in vitro.
Michele K. Wu, Hideyuki Hyogo, Suresh K. Yadav, Phyllis M. Novikoff, David E. Cohen   +4 more
doaj   +1 more source

Phospholipid Species in Newborn and 4 Month Old Infants after Consumption of Different Formulas or Breast Milk. [PDF]

PLoS ONE, 2016
INTRODUCTION:Arachidonic acid (AA) and docosahexaenoic acid (DHA) are important long-chain polyunsaturated fatty acids for neuronal and cognitive development and are ingredients of infant formulae that are recommended but there is no evidence based ...
Olaf Uhl, Manja Fleddermann, Christian Hellmuth, Hans Demmelmair, Berthold Koletzko   +4 more
doaj   +1 more source