Results 101 to 110 of about 82,133 (342)

Data from: Amadori-glycated phosphatidylethanolamine enhances the physical stability and selective targeting ability of liposomes

, 2018
Liposomes consisting of 100% phosphatidylcholine exhibit poor membrane fusion, cellular uptake and selective targeting capacities. To overcome these limitations, we used Amadori-glycated phosphatidylethanolamine, which is universally present in animals ...
Yurika Otoki, Kiyotaka Nakagawa, Naoki Shimizu, Taiki Miyazawa, Kato, Shunji, Teruo Miyazawa, Takahiro Harigae, Junya Ito, Shunji Kato, Miyazawa, Taiki, Shimizu, Naoki, Nakagawa, Kiyotaka, Miyazawa, Teruo, Harigae, Takahiro, Kamiyoshihara, Reina, Reina Kamiyoshihara, Otoki, Yurika, Ito, Junya   +17 more
core   +1 more source

Synthesis of photoreactive phosphatidylethanolamine and its interaction with phospholipase A₂

, 1994
A photoreactive derivative of phosphatidylethanolamine, N-(4-azidobenzoyl)phosphatidylethanolamine (AB-PE), was synthesized by acylation of phosphatidylethanolamine with an N-hydroxysuccinimide ester of 4-azidobenzoic acid.
Kemp, J. D., Rajasekharan, R.
core   +1 more source

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

Interdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu, Zhouyu Ning, Yong Deng, Changjing Huang, Hui Li, Yun Sun, Zhiqiang Meng   +6 more
wiley   +1 more source

Synthesis of Isoprostanyl Phosphatidylcholine and Isoprostanyl Phosphatidylethanolamine

, 2016
The syntheses of two isoprostanyl phospholipids are described. A newly established route to 15-F2t-isoprostane and ent-15-epi-F2t-isoprostane has allowed for the selective preparation of 15-F2t-isoprostanyl phosphatidylethanolamine and ent-15-epi-F2t ...
Thomas O. Schrader (1706734), Manami Shizuka (2650621), Marc L. Snapper (2076160)   +2 more
core   +1 more source

Hybrid Quatsome‐Encapsulated Silver Nanoparticles as Stable Plasmonic Substrates for Surface‐Enhanced Raman Scattering

Journal of Raman Spectroscopy, EarlyView.
In this work, silver nanoparticles encapsulated within quatsome membranes have shown to preserve their plasmonic properties for at least 165 days without aggregation. These hybrid nanostructures enable strong SERS enhancement of pyrene and Prodan by confining the molecules within a few nanometers from the silver surface.
Renato Cezar Peramezza Ribeiro, Caio Hiroaki Miyake, Pedro Henrique Figueiredo Backes Costa, Jhenifer Hallen Braga Mauricio, Ana Luiza Correa Januário, Diogo Soga, Evandro Luiz Duarte, Márcia de Almeida Rizzutto, Rômulo Augusto Ando, Antonio Rodrigues da Cunha, Erix Alexander Milán‐Garcés   +10 more
wiley   +1 more source

LPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu, Xiao‐Bo Wan, Yong‐Shun Liang, Tian Lan, Hao Liang   +4 more
wiley   +1 more source

Effect of angiotensin II non-peptide AT1 antagonist losartan on phosphatidylethanolamine membranes.

, 2000
Losartan was found to affect both the thermotropic behavior and molecular mobility of dimyristoyl- and dipalmitoyl-phosphatidylcholine membranes (Theodoropoulou and Marsh, Biochim. Biophys. Acta 1461 (1999) 135–146). At low concentrations, the antagonist
Theodoropoulou, E., Derek Marsh, Marsh, D., Theodoropoulou, Efthimia, Efthimia Theodoropoulou, Marsh, Derek   +5 more
core   +1 more source

Phosphatidylethanolamine: A key player in lung disease

Clinical and Translational Discovery
Phosphatidylethanolamine (PE) is a pivotal glycerophospholipid that constitutes a significant portion of cellular membranes, playing a crucial role in maintaining membrane fluidity, supporting protein integration, and mediating signal transduction.
Linlin Zhang, Wanxin Duan, Liyang Li
doaj   +1 more source

Can calmodulin bind to lipids of the cytosolic leaflet of plasma membranes?

Open Biology
Calmodulin (CaM) is a ubiquitous calcium-sensitive messenger in eukaryotic cells. It was previously shown that CaM possesses an affinity for diverse lipid moieties, including those found on CaM-binding proteins. These facts, together with our observation
Federica Scollo, Carmelo Tempra, Hüseyin Evci, Miguel Riopedre-Fernandez, Agnieszka Olżyńska, Matti Javanainen, Arunima Uday, Marek Cebecauer, Lukasz Cwiklik, Hector Martinez-Seara, Pavel Jungwirth, Piotr Jurkiewicz, Martin Hof   +12 more
doaj   +1 more source

Lipidomic Analysis Reveals Serum Alteration of Plasmalogens in Patients Infected With ZIKA Virus

Frontiers in Microbiology, 2019
Zika virus (ZIKV) is an arthropod-borne virus (arbovirus) in the Flavivirus genus of the Flaviviridae family. Since the large outbreaks in French Polynesia in 2013–2014 and in Brazil in 2015, ZIKV has been considered a new public health threat.
Adriano Queiroz, Isabella Fernanda Dantas Pinto, Maricélia Lima, Marta Giovanetti, Marta Giovanetti, Jaqueline Goes de Jesus, Joilson Xavier, Fernanda Khouri Barreto, Gisele André Baptista Canuto, Helineide Ramos do Amaral, Ana Maria Bispo de Filippis, Denise Lima Mascarenhas, Melissa Barreto Falcão, Normeide Pedreira Santos, Vasco Ariston de Carvalho Azevedo, Marcos Yukio Yoshinaga, Sayuri Miyamoto, Luiz Carlos Junior Alcantara, Luiz Carlos Junior Alcantara, Luiz Carlos Junior Alcantara   +19 more
doaj   +1 more source