Results 81 to 90 of about 85,741 (244)

Proton-Induced Fusion of Oleic Acid-Phosphatidylethanolamine Liposomes

, 1985
Liposomes composed of oleic acid and phosphatidylethanolamine (3:7 mole ratio) aggregate, become destabilized, and fuse below pH 6.5 in 150 mM NaCl.
Baldwin, Patricia A., Papahadjopoulos, Demetrios, Friend, Daniel S., Düzgüneş, Nejat, Straubinger, Robert M.   +4 more
core   +1 more source

SIRT5‐Mediated Desuccinylation of ACAA2 Protects Against Calcium Oxalate‐Induced Kidney Injury by Regulating Fatty Acid Oxidation to Suppress Mitochondrial Oxidative Injury and Ferroptosis

Advanced Science, EarlyView.
The SIRT5/ACAA2 axis maintains lipid metabolic homeostasis in RTECs by promoting ACAA2 desuccinylation and preserving its stability and enzymatic activity, thereby sustaining FAO and limiting PUFA and PUFA‐containing phospholipid accumulation. Under CaOx stress, SIRT5 downregulation impairs FAO, promotes oxidative stress and ferroptosis, and enhances ...
Qinhong Jiang, Caitao Dong, Yuchen Liu, Yuanquan Lou, Wenlong Lin, Sheng Li, Ziqi He   +6 more
wiley   +1 more source

Lipidomic analysis of bloodstream and procyclic form Trypanosoma brucei [PDF]

, 2010
The biological membranes of Trypanosonza brucei contain a complex array of phospholipids that are synthesized de novo from precursors obtained either directly from the host, or as catabolised endocytosed lipids.
Gibellini, Federica, TERRY K. SMITH, FEDERICA GIBELLINI, Lilley, Alison, SIMON A. YOUNG, Richmond, Gregory S., Major, Louise, Denton, Helen, Smith, Terry K, HELEN DENTON, Young, Simon A., GREGORY S. RICHMOND, LOUISE MAJOR, ALISON LILLEY, Young, Simon A.; id_orcid, Smith, Terry K; id_orcid, Major, Louise; id_orcid   +16 more
core   +1 more source

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

Advanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao, Zhangrong Cheng, Xianglong Chen, Wenbo Wu, Wang Wu, Zimu Yu, Cao Yang, Yukun Zhang   +7 more
wiley   +1 more source

Astrocyte‐Associated ABCA1/APOE Responses Accompany Hippocampal Lipid Remodeling and Ectopic Neuronal Accumulation During Epileptogenesis

Advanced Science, EarlyView.
During kainic acid‐induced epileptogenesis, astrocyte‐associated ATP‐binding cassette transporter A1 (ABCA1) and apolipoprotein E (APOE) responses accompany ectopic neurons and exploratory lipid alterations. In separate cohorts, bexarotene pretreatment and treatment on days 14–21 are associated with fewer ectopic hilar neurons and lower chronic seizure
Lu Chen, Xiao‐Rui Shi, Jia‐Yi Chen, Ying‐Ting Wang, Le Du, Yang Ni, Jun‐Min Chen, An‐Chen Guo, Qian Wu, Jian‐Ping Wu, Qun Wang   +10 more
wiley   +1 more source

Comparison of erythrocyte membrane phosphatidylethanolamine lipids levels according to dominance of positive or negative symptoms.

, 2016
Comparison of erythrocyte membrane phosphatidylethanolamine lipids levels according to dominance of positive or negative symptoms.
Jae-Min Kim (112584), Min Jhon (2559721), Stefan Smesny (2136697), Michael Berk (343706), Sung-Wan Kim (112587), Claudia M. Klier (2136712), G. Paul Amminger (2136709), Simon Rice (2559718), Miriam R. Schäfer (2136718), Patrick D. McGorry (717772)   +9 more
core   +1 more source

Minimal system to covalently bind the protein Atg8 via an ubiquitin-like reaction to phosphatidylethanolamine (PE).

, 2014
Minimal system to covalently bind the protein Atg8 via an ubiquitin-like reaction to phosphatidylethanolamine (PE).
Roland L. Knorr (178019), Hitoshi Nakatogawa (676830), Reinhard Lipowsky (178033), Yoshinori Ohsumi (228984), Tobias Baumgart (183997), Rumiana Dimova (178026)   +5 more
core   +1 more source

Compartmentation of Newly Synthesized Phosphatidylethanolamine in Rat Brain Microsomes

, 1986
The compartmentation of the phosphatidylethanolamine newly synthesized in brain microsomes in vitro either by base exchange or net synthesis has been studied, using difluorodinitrobenzene as a chemical probe.
ROBERTI, Rita, ARIENTI, Giuseppe, L. Freysz, BINAGLIA, Luciano, CORAZZI, Lanfranco, PORCELLATI, Giuseppe   +5 more
core  

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Fasting and Refeeding Mediated Phospholipid Remodeling Plays an Important Role in Improving Meat Quality of Aged Laying Hens

Animal Research and One Health, EarlyView.
ABSTRACT This study explored fasting‐induced physiological remodeling effects on meat quality in aged laying hens. Fasting for 15 days (F15) significantly reduced abdominal fat, intermuscular fat width, subcutaneous fat thickness, and liver index versus pre‐fasting (F0) (p < 0.05), which recovered post‐refeeding.
Xiaoran Zhang, Jun Zhang, Yadong Tian, Donghua Li, Yanhua Zhang, Lujie Zhang, Yujie Gong, Xiangtao Kang, Ruirui Jiang   +8 more
wiley   +1 more source