Results 71 to 80 of about 85,741 (244)

Studies on Hydrolysis of Phosphatidylethanolamine in Rat Small Intestinal Smooth Muscle [PDF]

Studies on enzymatic hydrolysis of phosphatidylethanolamine in rat small intestinal smooth muscle were carried out in comparison with that in the small intestinal mucosa.
西村, 護
core   +1 more source

ACSL4‐Dependent Lysosomal Lipid Peroxidation Links WTAP‐Mediated m6A Modification to Intervertebral Disc Degeneration

Advanced Science, EarlyView.
IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia, Xu Gao, Laimin Zhu, Haixia Song, Jing Wu, Shang Chen, Sheng Gao, Lu Zhang, Chunyang Meng   +8 more
wiley   +1 more source

Interactions in mixed monolayers between distearoyl- l-phosphatidylethanolamine, rod outer segment phosphatidylethanolamine and all- trans retinal. Effect of pH

, 1983
The interactions in mixed monolayers between distearoyl- l-phosphatidylethanolamine, natural phosphatidylethanolamine purified from bovine rod outer segments and all- trans retinal have been studied at the nitrogen/water interface at 21.0 ± 0.5° C ...
Leblanc, Roger M, Robert, Sylvain, Salesse, Christian, Tancrède, Pierre   +3 more
core   +1 more source

Enzymatic Characterization of Leishmania major Phosphatidylethanolamine Methyltransferases LmjPEM1 and LmjPEM2 [PDF]

, 2015
Phosphatidylcholine (PC) is the most abundant phospholipid in the membranes of the human parasite Leishmania. It is synthesized via two metabolic routes, the de novo pathway that starts with the uptake of choline, and the threefold methylation of ...
Dahlstrom, Kelly, Bibis, Stergios S., Zhu, Tongtong, Zufferey, Rachel   +3 more
core   +1 more source

Ultrasound‐Activated Nanoinhibitors Blocking the Chemo‐Immune Checkpoint to Overcome Chemotherapy‐Induced Immune Resistance

Advanced Science, EarlyView.
A sono‐responsive chemo‐immune checkpoint nanoinhibitor (Sono‐TT8) co‐delivering TPZ chemotherapy and siXkr8 simultaneously kills tumor cells and blocks PS externalization, reversing chemotherapy‐induced immunosuppression and enhancing antitumor immunity. ABSTRACT Breast cancer features an immunosuppressive tumor microenvironment following chemotherapy
Yunfan Liu, Chier Du, Leilei Zhu, Hongjin An, Shengzhe Hou, Yi Lan, Xuemei Tang, Min Xu, Peng Luo, Hua Teng, Hao Yang, Xun Guo, Jianli Ren, Zhiyi Zhou   +13 more
wiley   +1 more source

Extracellular Vesicles: Budding Regulated by a Phosphatidylethanolamine Translocase

, 2011
SummaryRecent work on a Caenorhabditis elegans transmembrane ATPase reveals a central role for the aminophospholipid phosphatidylethanolamine in the production of a class of extracellular ...
Simon Tuck, Tuck, Simon,
core   +1 more source

Sex‐ and Time‐Resolved Physiological and Gut Ecosystem Responses to a Food‐Grade Microbiome‐Targeted Intervention in Collegiate Endurance Athletes

Advanced Science, EarlyView.
In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang, Le Ge, Kaiyang Liu, Yanrong Liu, Guolin Zhao, Lai‐Yu Kwok, Zheng Sun, Zhihong Sun, Wenyi Zhang   +8 more
wiley   +1 more source

Plasmodium knowlesi induces alterations in phosphatidylcholine and phosphatidylethanolamine molecular species composition of parasitized monkey erythrocytes

, 1990
International audienceUsing high performance liquid chromatograpy and gas-liquid chromatography, we have characterized the phosphatidylcholine and phosphatidylethanolamine molecular species composition of trophozoite and schizont forms of Plasmodium ...
Roelofsen, B., Moll, G.N., Op den Kamp, J.A.F., Beaumelle, B., Vial, H.J., Simões, A.P.   +5 more
core   +1 more source

Stable isotopic tracer phospholipidomics reveals contributions of key phospholipid biosynthetic pathways to low hepatocyte phosphatidylcholine to phosphatidylethanolamine ratio induced by free fatty acids

, 2021
There is a strong association between hepatocyte phospholipid homeostasis and nonalcoholic fatty liver disease (NAFLD). The phosphatidylcholine to phosphatidylethanolamine ratio (PC/PE) often draws special attention as genetic and dietary disruptions to ...
KY Peng (10752246), MA Febbraio (9644273), NA Mellett (9856673), H Kammoun (10752252), Andrew Murphy (9477623), CK Barlow (10752249), JM Weir (10752255), PJ Meikle (9856718)   +7 more
core   +2 more sources

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

Advanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne, Aikta Sharma, Scott Dillon, Jacob Keen, Soher N. Jayash, Natalie Crump, Lucinda A.E. Evans, Maya Karmali, Worachet Promruk, Claire E. Clarkin, Sonoko Narisawa, Louise Stephen, Brian L. Foster, José Luis Millán, Colin Farquharson, Katherine A. Staines   +15 more
wiley   +1 more source