Results 131 to 140 of about 72,154 (294)
Increases in sphingomyelin in response to TDP‐43 pathology in the disease‐affected motor cortex of amyotrophic lateral sclerosis (ALS) brain. Abstract Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease characterized by the degeneration of motor neurons and the presence of TAR DNA‐binding protein 43 (TDP‐43 ...
Finula I. Isik +4 more
wiley +1 more source
Abstract 2311 Two Bridge-like lipid transfer proteins (BLTPs) transport phosphatidylethanolamine at membrane contact sites to facilitate GPI-anchored biogenesis and maintain plasma membrane fluidity [PDF]
Alexandre Toulmay +3 more
openalex +1 more source
Cannabidiol (CBD) and cannabigerol (CBG) alleviate hepatic steatosis in obese mice by shifting energy buffering towards phosphocreatine and enhancing lysosomal lipid degradation and trafficking. These effects are associated with increased creatine kinase activity and lysobisphosphatidic acid (LBPA) levels, highlighting a previously unrecognised ...
Radka Kočvarová +12 more
wiley +1 more source
An apo-E-free very low density lipoprotein enriched in phosphatidylethanolamine in human plasma.
P E Fielding, C J Fielding
openalex +1 more source
Carboxymethylated phosphatidylethanolamine in mitochondrial membranes of mammals [PDF]
Reinald Pamplona +5 more
openalex +1 more source
ABSTRACT Aims Circadian regulation of metabolism is an important factor in metabolic health, yet the role of rhythmic metabolites in Type 2 diabetes development remains poorly understood. This study investigated associations between circulating rhythmic metabolites and incident Type 2 diabetes risk and evaluated causal relationships using two‐sample ...
Divya Joshi +10 more
wiley +1 more source
Autophagy is a cellular degradation process involved in, for example, immune responses to pathogens and neurodegeneration. To identify modulators of autophagy, we developed a microscopy‐based screening assay and identified previously unknown autophagy‐modulating activities in known drugs and natural products from myxobacteria and fungi.
Janine Fichtner +13 more
wiley +1 more source
Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna +5 more
wiley +1 more source
Ceramide-C16 Is a Versatile Modulator of Phosphatidylethanolamine Polymorphism [PDF]
Mahmoudreza Doroudgar, Michel Lafleur
openalex +1 more source

