ABCA4 is an N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine importer [PDF]
Nature Communications, 2012 ATP-binding cassette (ABC) transporters comprise a superfamily of proteins, which actively transport a variety of compounds across cell membranes. Mammalian and most eukaryotic ABC transporters function as exporters, flipping or extruding substrates from the cytoplasmic to the extracellular or lumen side of cell membranes.
Quazi, Faraz +2 more
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SRC promotes lipogenesis: implications for obesity and breast cancer
Molecular & Cellular Oncology, 2021 Remodeling of lipid metabolism has been implicated in cancers; however, it remains obscure how the lipid metabolic pathways are altered by oncogenic signaling to affect tumor development. We have recently shown that proto-oncogene tyrosine-protein kinase
Shu-Yong Lin, Sheng-Cai Lin
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Animal, 2020 Ochratoxin A (OTA) is a mycotoxin produced by various species of Aspergillus and Penicillium. Ochratoxin A was classified as a group 2B carcinogen and is one of the major intestinal pathogenic mycotoxins. One of the most frequent modes of intoxication is
I. El Cafsi +6 more
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Phosphatidylethanolamine Levels and Regulation of Phosphatidylethanolamine N- Methyltransferase
Journal of Biological Chemistry, 1989 The activity of phosphatidylethanolamine (PE) N-methyltransferase in liver microsomes, measured using endogenous microsomal PE as a substrate, was elevated 2-fold in the choline-deficient state. However, methyltransferase activity assayed in the presence of a saturating concentration of phosphatidyl-N-mono-methylethanolamine or microsomal PE was ...
N D, Ridgway, Z, Yao, D E, Vance
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UV analysis of Amadori-glycated phosphatidylethanolamine in foods and biological samples
Journal of Lipid Research, 2002 Maillard reactions are among the most important of the chemical and oxidative changes occurring in food and biological samples that contribute to food deterioration and to the pathophysiology of human disease.
Jeong-Ho Oak +2 more
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Physiological consequences of disruption of mammalian phospholipid biosynthetic genes
Journal of Lipid Research, 2009 By 1959, Eugene Kennedy and coworkers had outlined most pathways of phospholipid biosynthesis. In the next four decades, the emphasis was on enzymology and regulation of these pathways.
Dennis E. Vance, Jean E. Vance
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Lantibiotics as probes for phosphatidylethanolamine [PDF]
Amino Acids, 2009 Phosphatidylethanolamine (PE) is a major component in the mammalian plasma membrane. It is present mainly in the inner leaflet of the membrane bilayer in a viable, typical mammalian cell. However, accumulating evidence indicates that a number of biological events involve PE externalization.
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Turnover of nonessential fatty acids in cardiolipin from the rat heart
Journal of Lipid Research, 2011 Cardiolipin (CL) is a unique phospholipid (PL) found in the mitochondria of mammalian cells. CL remodeling is accompanied by turnover of its fatty acid acyl groups. Abnormalities in CL remodeling have been found in Barth's syndrome, diabetes, and obesity.
Paulin N. Wahjudi +8 more
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Dysregulated Choline, Methionine, and Aromatic Amino Acid Metabolism in Patients with Wilson Disease: Exploratory Metabolomic Profiling and Implications for Hepatic and Neurologic Phenotypes. [PDF]
, 2019 Wilson disease (WD) is a genetic copper overload condition characterized by hepatic and neuropsychiatric symptoms with a not well-understood pathogenesis.
Czlonkowska, Anna +6 more
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Enzymatic measurement of phosphatidylserine in cultured cells
Journal of Lipid Research, 2012 Phosphatidylserine (PS) is a quantitatively minor membrane phospholipid involved in diverse cellular functions. In this study, we developed a new fluorometric method for measuring PS using combinations of specific enzymes and Amplex Red.
Shin-ya Morita +6 more
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