Results 191 to 200 of about 391,487 (338)

ROBUST IN VITRO REPLICATION OF PLASMODIUM FALCIPARUM IN GLYCOSYL-PHOSPHATIDYLINOSITOL–ANCHORED MEMBRANE GLYCOPROTEIN–DEFICIENT RED BLOOD CELLS [PDF]

, 2003
Kovit Pattanapanyasat, Douglas S. Walsh, Kosol Yongvanitchit, NATAWAN PIYAWATTHANASAKUL, Wanchai Wanachiwanawin, H. Kyle Webster   +5 more
openalex   +1 more source

Detecting FR‐⍺ Expression Level in Cytology Effusion Specimens From Ovarian Cancer and Comparing It With Tissue Specimens

Diagnostic Cytopathology, EarlyView.
ABSTRACT Background Folate receptor‐⍺ (FR‐⍺) is an attractive target for targeted therapy. Mirvetuximab soravtansine (MIRV) has been approved by the United States Food and Drug Administration (FDA) for treating adult patients with FR‐⍺ positive, platinum‐resistant epithelial ovarian cancer, fallopian tube cancer, or primary peritoneal cancer. Therefore,
Yadan Ma, Xiaofei Yu, Xiaohong Duan, Siqian Huang, Sishi Bai, Baizhou Li   +5 more
wiley   +1 more source

Identifying the mediating role of immune cells on the relationship between plasma lipidomes and PCOS: a two-step Mendelian randomization analysis. [PDF]

J Ovarian Res
Liu L, Liu B, Li M, Qin L.
europepmc   +1 more source

RpkA, ein endosomaler G-Protein-gekoppelter Rezeptor [PDF]

, 2009
Riyahi, Tanja Yasmin
core  

Supplementary Table 1 and 2 from First-in-Human Phase I Study of GSK2126458, an Oral Pan-Class I Phosphatidylinositol-3-Kinase Inhibitor, in Patients with Advanced Solid Tumor Malignancies

, 2023
Pamela N. Münster, Rahul Aggarwal, David S. Hong, Jan H.M. Schellens, Ruud van der Noll, Jennifer M. Specht, Petronella O. Witteveen, Theresa L. Werner, E. Claire Dees, Emily K. Bergsland, Neeraj Agarwal, Joseph F. Kleha, Michael Durante, Laurel M. Adams, Deborah A. Smith, Thomas A. Lampkin, Shannon R. Morris, Razelle Kurzrock   +17 more
openalex   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

The Role of a Newly Synthesized Antimicrobial Peptide (KK)₂-KWWW-NH₂ in Modulating Phosphatidylinositol Monolayer Properties in the Presence of Ascorbic Acid. [PDF]

Int J Mol Sci
Golonka I, Sebastiańczyk A, Łukasiewicz IW, Greber KE, Sawicki W, Musiał W.   +5 more
europepmc   +1 more source

Data from Gene Expression Patterns in Mismatch Repair-Deficient Colorectal Cancers Highlight the Potential Therapeutic Role of Inhibitors of the Phosphatidylinositol 3-Kinase-AKT-Mammalian Target of Rapamycin Pathway

, 2023
Eduardo Vilar, Bhramar Mukherjee, Rork Kuick, Leon Raskin, David E. Misek, Jeremy M. G. Taylor, Thomas J. Giordano, Samir Hanash, Eric R. Fearon, Gad Rennert, Stephen B. Gruber   +10 more
openalex   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Pescadillo ribosomal biogenesis factor 1 as a therapeutic target in tumor immunotherapy. [PDF]

World J Gastroenterol
Yu J, Yu B, Ge FL, Ren ZG.
europepmc   +1 more source