Results 191 to 200 of about 188,850 (296)
Chinese medicine monomers for hepatocellular carcinoma: New ideas related to autophagy. [PDF]
Zheng SH+4 more
europepmc +1 more source
Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis
The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang+7 more
wiley +1 more source
Characteristics of a Phosphatidylinositol Exchange Activity of Soybean Microsomes [PDF]
Anna Stina Sandelius, D. James Morré
openalex +1 more source
Dysregulation of Monounsaturated Fatty Acids is Related to α‐Synuclein in Multiple System Atrophy
Abstract Background Multiple system atrophy (MSA) is a neurodegenerative disease pathologically characterized by the presence of glial cytoplasmic inclusions (GCI) composed of α‐synuclein aggregates. In Parkinson's disease, increases in monounsaturated fatty acids (MUFA) in phospholipid membranes promote α‐synuclein binding, aggregation, and toxicity ...
Finula I. Isik+8 more
wiley +1 more source
Genome-Wide Association Analysis of Flavor Precursor Traits in Chengkou Mountain Chicken. [PDF]
Wang H+7 more
europepmc +1 more source
Abstract Background Biallelic loss‐of‐function variants in PI4K2A have been associated with a neurodevelopmental disorder characterized by seizures and movement disorders, including orofacial dyskinesia. However, only 4 cases have been reported. Orolingual dyskinesia—defined as involuntary movements of the mouth and tongue—is observed in various ...
Reza Maroofian+9 more
wiley +1 more source
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro+5 more
wiley +1 more source