Results 191 to 200 of about 363,126 (392)

Longitudinal Proteomic Profiling of Cognition across an Aerobic Exercise Intervention

open access: yesAnnals of Neurology, Volume 97, Issue 5, Page 1007-1018, May 2025.
The physiological basis of cognitive decline remains largely uncharacterized. We identified a protein panel signature, in living humans, that correlates to improvement in neurocognition over a period of 5 years. Our signature is composed of complement proteins, coagulation cascade, and extracellular matrix regulators.
Alison M. H. Donald   +16 more
wiley   +1 more source

A type II phosphatidylinositol-4-kinase coordinates sorting of cargo polarizing by endocytic recycling

open access: yesCommunications Biology
Depending on their phosphorylation status, derivatives of phosphatidylinositol play important roles in vesicle identity, recognition and intracellular trafficking processes.
Anezia Kourkoulou   +3 more
doaj   +1 more source

Spatiotemporal Super‐Resolution Imaging of Lipid Metabolism Dynamics in Physiological/Pathological Conditions

open access: yesAngewandte Chemie International Edition, Accepted Article.
Dysregulated lipid metabolism plays a critical role in the pathogenesis of numerous diseases. However, due to the lack of effective solutions, the dynamic monitoring and deep understanding of lipid metabolism in the progression of diseases has remained challenging.
Shixian Cao   +7 more
wiley   +1 more source

Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase

open access: yesScience Translational Medicine, 2017
Tanya Paquet   +52 more
semanticscholar   +1 more source

Shennong 1 Chicken 40K Liquid Chip: Advancing Genetic Research in Chinese Indigenous Chickens

open access: yesAnimal Research and One Health, EarlyView.
Based on comprehensive genomic data of Chinese indigenous chickens, we developed a specialized genotyping array for this population. Comparative analyses with published mainstream arrays and evaluations, including genetic assessment of diverse chicken types and gene mining analyses, demonstrated its superior applicability to Chinese indigenous chickens.
Chaoqun Gao   +14 more
wiley   +1 more source

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