Results 241 to 250 of about 391,487 (338)

Adenovirus E4ORF1 activates isoform-specific phosphatidylinositol 3-kinase signaling in human endothelial cells. [PDF]

J Biol Chem
Geng F, Kobayashi M, Lin Y, Gomez-Salinero JM, Romano D, Kanyo J, Geng J, Liu Y, Ginsberg M, Shieh JH, Chen K, Lam TT, Rafii A, Rabbany SY, Lis R, Rafii S.   +15 more
europepmc   +1 more source

Peripheral versus Marrow Lipidomics in Patients with Severe Aplastic Anemia: Potential Indicators for Early Immunosuppressive Treatment Response

Lipids, EarlyView.
ABSTRACT This study aimed to explore the differences of peripheral blood (PB) and bone marrow serum lipidomic profiles in severe aplastic anemia (SAA) patients and their significance in predicting earlier immunosuppressive therapy (IST) response. A cohort of 11 newly diagnosed SAA patients and 15 healthy controls were enrolled between June 2020 and ...
Zexing Sun, Yilei Hong, Yaonan Hong, Chuanao Xin, Qi Liu, Huijin Hu, Yingying Shen, Ying Chen, Shan Liu, Yiping Shen, Yuhong Zhou, Dijiong Wu   +11 more
wiley   +1 more source

Heat shock-induced PI(4)P increase drives HSPA1A translocation to the plasma membrane in cancer and stressed cells through PI4KIII alpha activation. [PDF]

Cell Stress Chaperones
Arce A, Altman R, Badolian A, Low J, Cuaresma AB, Halkia G, Keshet U, Fiehn O, Stahelin RV, Nikolaidis N.   +9 more
europepmc   +1 more source

The Inhibitory Effect of Dibutyryl Cyclic AMP on Docosahexaenoic Acid-Induced Apoptosis in HL-60 Cells through Activation of the Phosphatidylinositol-3 Kinase Pathway [PDF]

, 2005
Yoshie Miura, Yoshiyuki Murata, Kozo Utsumi, Kyoya Takahata, Mikiro Tada, Takemi Otsuki   +5 more
openalex   +1 more source

A Lipidomic Analysis Reveals Dynamic Changes of Polar Lipids for Oil Biosynthesis During Cotyledon Development in <i>Perilla frutescens</i>. [PDF]

Plants (Basel)
Liu X, Zhang J, Xu W, Du X, Yang D, Xu L, Zhang S, Gao T.   +7 more
europepmc   +1 more source

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source

Protective effects of traditional Chinese medicines Aconiti Lateralis Radix Praeparata and Angelicae Sinensis on H/R cardiomyocytes via the PI3K/Akt/GSK-3β pathway and autophagy pathway. [PDF]

Medicine (Baltimore)
Cao Y, Ge J, Meng G, Shi H, Zhang J, Cao X, Liang X.   +6 more
europepmc   +1 more source

Enhancing Selective Brain Cancer Therapy: Integrating Nanomedicine and Molecular Dynamics to Target the Cancerous Lipid Composition

Nano Select, EarlyView.
Improving selectivity within therapeutic design is critical to ensure targeted delivery to brain tumors. Targeting the cellular membrane composition distinctive of the blood–brain barrier and brain cancer cells is explored in this review. Nanomedicine can be utilized for precise tumor recognition, and detailed mechanistic interactions of therapeutics ...
Mahnoor Kadri, Dominique de Jong‐Hoogland, Martin B. Ulmschneider   +2 more
wiley   +1 more source

Integrated lipidomics and proteomics analysis in the cardiac surgery-associated acute kidney injury. [PDF]

Ren Fail
Zhou F, Xu Y, Zhang S, Wang L, Zheng X, Ding W, Ma H, Luo Q.   +7 more
europepmc   +1 more source

Resveratrol Inhibits LPS-Induced MAPKs Activation via Activation of the Phosphatidylinositol 3-Kinase Pathway in Murine RAW 264.7 Macrophage Cells

, 2012
Yi Zong, Lin Sun, Bin Liu, Yishu Deng, Dong Zhan, Yuanli Chen, Ying He, Jing Liu, Zhang Zong-ji, Jun Sun, Di Lü   +10 more
openalex   +2 more sources