Results 261 to 270 of about 375,434 (302)
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Phosphatidylinositol 4-kinases, phosphatidylinositol 4-phosphate and cancer
Cancer Letters, 2012This article focuses on the emerging roles for phosphatidylinositol 4-phosphate and the phosphatidylinositol 4-kinases in cancer. Phosphatidylinositol 4-phosphate is a common substrate for both the phosphatidylinositol 3-kinase and phospholipase C pathways, and has been implicated in the membrane targeting of proteins such as Girdin/GIV and OSBP ...
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Biochemical and Biophysical Research Communications, 1986
We have previously found that concanavalin A binds specifically to inositol and phosphatidylinositol. In the present study we demonstrate that binding of concanavalin A to liposomes containing phosphatidylinositol influences the uptake of such liposomes by macrophages.
N M, Wassef, C R, Alving
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We have previously found that concanavalin A binds specifically to inositol and phosphatidylinositol. In the present study we demonstrate that binding of concanavalin A to liposomes containing phosphatidylinositol influences the uptake of such liposomes by macrophages.
N M, Wassef, C R, Alving
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Anti‐inflammatory actions of phosphatidylinositol
European Journal of Immunology, 2011AbstractChronic inflammatory T‐cell‐mediated diseases such as inflammatory bowel disease (IBD) are often treated with immunosuppressants including corticosteroids. In addition to the intended T‐cell suppression, these farmacons give rise to many side effects. Recently, immunosuppressive phospholipids have been proposed as less‐toxic alternatives.
Dieren, Jolanda +12 more
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The structural requirement of phosphatidylinositols as substrate of phosphatidylinositol 3-kinase
Tetrahedron Letters, 1999Abstract Synthetic distearate phosphatidylinositol (PI) was not phosphorylated by PI 3-kinase. The fatty acids at glycerol sn -2 must be as short as octanoic acid or less to act as a substrate of PI 3-kinase.
Ryuichi Shirai +6 more
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Phosphatidylinositol phosphate kinases.
Journal of endocrinological investigation, 2004Phosphatidylinositol 4,5-bisphosphate is a multi-functional lipid, whose proposed functions now number more than twenty, covering many aspects of cell biology in several different subcellular compartments. The enzymes primarily responsible for synthesizing this lipid, the Type I phosphatidylinositol 4-phosphate 5-kinases, are therefore a tightly ...
Giudici, ML, Hinchliffe, KA, Irvine, RF
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Phosphatidylinositol-transfer protein and cellular phosphatidylinositol metabolism
Biochemical Society Transactions, 1987P A, Van Paridon +2 more
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Effect of neomycin on glycosyl-phosphatidylinositol and phosphatidylinositol system of Tetrahymena.
Microbios, 1996Neomycin does not inhibit but increases the incorporation of 32P into phosphatidylinositols of Tetrahymena. This elevation is due to neomycin inhibition on the turnover of the phosphatidylinositol (PI) system. Neomycin also prevents the synthesis of glycosyl-phosphatidylinositol (GPI).
P, Kovács, G, Csaba
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Review of Phosphatidylinositol Phosphate Kinase in Phosphatidylinositol Signaling Pathway
2014Phosphatidylinositol signaling pathway is an important signal transduction pathway that plays critical roles in multiple cell processes first demonstrated in animal cells. Research evidences have shown that although not exactly the same as it is in yeast and mammalian cells, phosphatidylinositol signaling pathway also exists in plant cells and is ...
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Journal of cellular physiology, 2016
Phosphatidylinositol (PI) metabolism represents the core of a network of signaling pathways which modulate many cellular functions including cell proliferation, cell differentiation, apoptosis, and membrane trafficking. An array of kinases, phosphatases, and lipases acts on PI creating an important number of second messengers involved in different ...
POLI, ALESSANDRO +7 more
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Phosphatidylinositol (PI) metabolism represents the core of a network of signaling pathways which modulate many cellular functions including cell proliferation, cell differentiation, apoptosis, and membrane trafficking. An array of kinases, phosphatases, and lipases acts on PI creating an important number of second messengers involved in different ...
POLI, ALESSANDRO +7 more
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Biosynthesis of glycosyl-phosphatidylinositol
Cell Biology International Reports, 1991openaire +2 more sources