Targeting the Osteopontin-regulated PI3K/AKT signaling pathway: A molecular approach to overcome drug resistance and metastasis in gastrointestinal tumors. [PDF]
Nian H +9 more
europepmc +1 more source
Investigation of the Pathomechanism of Chronic Cough Using an In Vitro Approach
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 247-249, March 2025.
Umesh Singh, Jonathan A. Bernstein
wiley +1 more source
Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth +5 more
wiley +1 more source
Quercetin in the control and treatment of membranous nephropathy by regulating phosphatidylinositol 3-kinase/protein kinase-B signaling pathway. [PDF]
Shen L, Ding S, Zhang L, Wang G, Zou Y.
europepmc +1 more source
ABSTRACT Hydrogen gas (H2) effectively alleviates abiotic stress in horticultural plants. Protein S‐nitrosylation, a key post‐translational modification, serves as a critical mechanism for nitric oxide (NO) to exert its biological function under adverse conditions.
Hua Fang +12 more
wiley +1 more source
Ubiquitin C-terminal hydrolase L5 promotes the development of renal cell carcinoma through the glycolysis mediated by the phosphatidylinositol-3-kinase/protein kinase B/mammalian target of rapamycin pathway. [PDF]
Ruan L, Li S, Xu L.
europepmc +1 more source
ABSTRACT Cold stress threatens wheat productivity, particularly in regions with extreme climatic conditions. To elucidate the molecular mechanisms underlying wheat's response to cold stress, we performed a multiomics analysis integrating lipidomics, transcriptomics, proteomics and metabolomics.
Sofora Jan +15 more
wiley +1 more source
Lipids regulate epidermal growth factor receptor activation by its ligands. [PDF]
Hutchison JM, Lemmon MA.
europepmc +1 more source
Sweet Potato Gene Clusters Control Anthocyanin Biosynthesis and Leaf Morphology
ABSTRACT Sweet potato (Ipomoea batatas) exhibits diversity in pigmentation and leaf morphology, yet the genetic architecture and regulatory organisation underlying these traits remain poorly resolved, particularly with respect to organ‐specific control.
Dong An +13 more
wiley +1 more source
ABSTRACT Thermo‐sensitive genic male sterility (TGMS) lines play a pivotal role in two‐line hybrid rice breeding. However, the availability of elite TGMS germplasm remains limited, and the molecular mechanisms underlying fertility transition of TGMS lines are still poorly understood.
Siqi Cheng +33 more
wiley +1 more source

