Results 261 to 270 of about 405,250 (376)
Cancer Science, EarlyView.IRF4 is a prognostic biomarker in cervical cancer. IRF4 enhances radiosensitivity and inhibits tumor growth via PI3K/AKT/mTOR‐mediated autophagy. IRF4 boosts radiation response in vitro and in vivo. ABSTRACT Interferon regulatory factor 4 (IRF4), a critical member of the IRF transcription factor family, harbors an elusive biological role in cervical ...
Meihui Gao +9 more
wiley +1 more source
Cell Proliferation, EarlyView.PIK‐III enhancing the efficacy of cuproptosis to kill renal cancer cells through dysregulating thiamine metabolism and dephosphorylation of pyruvate dehydrogenase complex E1 (PDHA1), providing a potential option for treatment of cuproptosis‐resistant renal cancer by the combination of PIK‐III and elesclomol.
Dongdong Xie +8 more
wiley +1 more source
Lipid signalling in plant development and responses to environmental stresses
Frontiers in Plant Science, 2016 Eric eRuelland +2 more
doaj +1 more source
Inositol metabolism as a broad-spectrum antiviral target. [PDF]
Front MicrobiolJitobaom K, Auewarakul P.
europepmc +1 more source
Diabetes, Obesity and Metabolism, EarlyView.Abstract Neurodegenerative diseases, including debilitating conditions like Alzheimer's and Parkinson's, are characterized by progressive neuronal loss, a process fundamentally driven by persistent chronic neuroinflammation and central metabolic dysfunction.
Renata Spezani +1 more
wiley +1 more source
Molecular insight on the role of the phosphoinositide PIP3 in regulating the protein kinases Akt, PDK1, and BTK. [PDF]
Biochem Soc TransShaw AL, Burke JE.
europepmc +1 more source
Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.
Biochemical Journal, 1998 P. Coffer, Jing-Yun Jin, J. Woodgett
semanticscholar +1 more source