Results 181 to 190 of about 192,293 (285)

Far‐infrared irradiation attenuates platelet‐derived growth factor‐stimulated vascular smooth muscle cell migration through protein phosphatase 2A‐mediated Akt inhibition

Photochemistry and Photobiology, EarlyView.
FIR irradiation enhances the physical association between Akt and PP2Ac in VSMCs, independent of the hyperthermal effect of FIR rays. The increased binding between Akt and PP2Ac induced by FIR irradiation facilitates the dephosphorylation of Akt at Ser473.
Na‐Young Lee, Seo‐Hyeon Kim, Young Jin Kang, Il‐Kug Kim, Yun‐Jin Hwang, Du‐Hyong Cho   +5 more
wiley   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

Phosphatidylinositol 4-phosphate is a major source of GPCR-stimulated phosphoinositide production. [PDF]

Sci Signal, 2018
de Rubio RG, Ransom RF, Malik S, Yule DI, Anantharam A, Smrcka AV.   +5 more
europepmc   +1 more source

Fission yeast Opy1 is an endogenous PI(4,5)P₂ sensor that binds to the phosphatidylinositol 4-phosphate 5-kinase Its3.

J Cell Sci, 2020
Snider CE, Willet AH, Brown HT, Chen JS, Evers JM, Gould KL.   +5 more
europepmc   +1 more source

The P5A ATPase Spf1p is stimulated by phosphatidylinositol 4-phosphate and influences cellular sterol homeostasis. [PDF]

Mol Biol Cell, 2019
Sørensen DM, Holen HW, Pedersen JT, Martens HJ, Silvestro D, Stanchev LD, Costa SR, Günther Pomorski T, López-Marqués RL, Palmgren M.   +9 more
europepmc   +1 more source

Integrative Phosphoproteomic Profiling Reveals Stage‐Specific Signalling and Metabolism in Equine Melanocytic Neoplasm

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Equine melanocytic neoplasms (EMN) are aggressive tumours characterised by high metastatic potential and limited therapeutic options available. However, the molecular mechanisms underlying their progression remain poorly understood. This study therefore presents the integrative phosphoproteomic analysis of EMN tissue, with the aim of ...
Paitoon Srimontri, Amornthep Kingkaw, Nawarus Prapaiwan, Rangsima Sujittosakul, Nichapat Iamkaewprasert, Jiraschaya Piputwat, Puetta Isama‐al, Thanutchanok Munkongdee, Thanapon Chotikaprakal, Petchpailin Yanyongsirikarn, Narumon Phaonakrop, Sittiruk Roytrakul, Wanwipa Vongsangnak, Parichart Tesena   +13 more
wiley   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

Isoproterenol modulates insulin activation of insulin receptor kinase in intact rat adipocytes [PDF]

, 1988
Klein, H. H., Matthaei, S., Scriba, Peter Christian   +2 more
core  

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

Ethanol targets nucleoredoxin/dishevelled interactions and stimulates phosphatidylinositol 4-phosphate production in vivo and in vitro. [PDF]

Biochem Pharmacol, 2018
Arellanes-Robledo J, Reyes-Gordillo K, Ibrahim J, Leckey L, Shah R, Lakshman MR.   +5 more
europepmc   +1 more source