Results 241 to 250 of about 195,175 (290)

Physiological roles of phosphoinositides and inositol phosphates: Implications for metabolic dysfunction-associated steatotic liver disease. [PDF]

Clin Sci (Lond)
Cheng Z, Montgomery MK.
europepmc   +1 more source

<i>PTEN</i> Gene and Autism: Genetic Underpinnings and Neurodevelopmental Impacts. [PDF]

Genes (Basel)
Genovese AC, Butler MG.
europepmc   +1 more source

Preferential use of alkyl-acyl phosphatidylinositol for GPI biosynthesis and diagnostic potential of lipidomics for inherited GPI deficiencies. [PDF]

J Biol Chem
Li X, Imanishi K, Umeshita S, Senoo Y, Guerrero PA, Silva DV, Ikeda K, Kinoshita T, Murakami Y.   +8 more
europepmc   +1 more source

Glycerophospholipid Profiles of <i>Allomyrina dichotoma</i> Larvae at Different Instars Based on Lipidomics and Transcriptomics Suggest a Promising Lipid Source. [PDF]

Insects
Fang K, Liu JN, Wang CX, Wang T, Pan Y, Wang S, Xi JH.   +6 more
europepmc   +1 more source

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Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

Nature, 1988
The generation of second messengers from the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdInsP2) by phosphoinositidase C has been implicated in the mediation of cellular responses to a variety of growth factors and oncogene products. The first step in the production of PtdInsP2 from phosphatidylinositol (PtdIns) is catalysed by PtdIns kinase.
M, Whitman, C P, Downes, M, Keeler, T, Keller, L, Cantley   +4 more
openaire   +4 more sources

Phosphatidylinositol and inositol phosphate metabolism

Journal of Cell Science, 2001
The six carbons that comprise the inositol ring can be phosphorylated in a combinatorial manner, generating a truly astonishing range of inositol phosphates and inositol lipids. Yet, somehow, the cell can distinguish and utilize several of these metabolites to specifically regulate a variety ...
K, Abel, R A, Anderson, S B, Shears
openaire   +2 more sources

Phosphatidylinositol 4-kinases, phosphatidylinositol 4-phosphate and cancer

Cancer Letters, 2012
This article focuses on the emerging roles for phosphatidylinositol 4-phosphate and the phosphatidylinositol 4-kinases in cancer. Phosphatidylinositol 4-phosphate is a common substrate for both the phosphatidylinositol 3-kinase and phospholipase C pathways, and has been implicated in the membrane targeting of proteins such as Girdin/GIV and OSBP ...
openaire   +2 more sources

Phosphatidylinositol‐4‐phosphate: The Golgi and beyond

BioEssays, 2013
Initially identified as a key phosphoinositide that controls membrane trafficking at the Golgi complex, phosphatidylinositol‐4‐phosphate (PI4P) has emerged as a key molecule in the regulation of a diverse array of cellular functions. In this review we will discuss selected examples of the findings that in the last few years have significantly increased
DE MATTEIS, Maria Antonietta, Wilson, Cathal, D'Angelo, Giovanni   +2 more
openaire   +3 more sources

Phosphatidylinositol phosphate kinases.

Journal of endocrinological investigation, 2004
Phosphatidylinositol 4,5-bisphosphate is a multi-functional lipid, whose proposed functions now number more than twenty, covering many aspects of cell biology in several different subcellular compartments. The enzymes primarily responsible for synthesizing this lipid, the Type I phosphatidylinositol 4-phosphate 5-kinases, are therefore a tightly ...
Giudici, ML, Hinchliffe, KA, Irvine, RF
openaire   +2 more sources