Results 171 to 180 of about 79,046 (379)

Myo‐Inositol Mitigates Oxidative Stress in Bovine Mammary Epithelial Cells via Activation of the SIRT5/Nrf2 Signaling Axis

Animal Research and One Health, EarlyView.
Myo‐inositol alleviates oxidative stress in dairy cow mammary epithelial cells via the Sirt5/Nrf2 pathway to promote mitochondrial fusion. This graphical abstract was created with BioRender.com. ABSTRACT High‐yielding dairy cows are susceptible to mammary gland oxidative stress due to prolonged intensive lactation, leading to redox imbalance.
Yufei Zhang, Yu Cao, Meng Zhang, Huijie Hu, He Ma, Junlong Bi, Juxiong Liu, Shoupeng Fu, Wenjin Guo   +8 more
wiley   +1 more source

A Conserved Role for Phosphatidylinositol 3-Kinase but Not Akt Signaling in Mitochondrial Adaptations that Accompany Physiological Cardiac Hypertrophy [PDF]

, 2007
Brian T. O’Neill, Jaetaek Kim, Adam R. Wende, Heather Theobald, Joseph Tuinei, Jonathan Buchanan, Aili Guo, Vlad G. Zaha, Don Davis, John C. Schell, Sihem Boudina, Benjamin Wayment, Sheldon E. Litwin, Tetsuo Shioi, Seigo Izumo, Morris J. Birnbaum, E. Dale Abel   +16 more
openalex   +1 more source

GPI anchor biosynthesis in yeast: phosphoethanolamine is attached to the α1,4-linked mannose of the complete precursor glycophospholipid [PDF]

, 2017
Cells synthesize the GPI anchor carbohydrate core by successively adding N-acetylglucosamine, three mannoses, and phosphoethanolamine (EtN-P) onto phosphatidylinositol, thus forming the complete GPI precursor lipid which is then added to proteins ...
Benachour, Abdellah, Burda, Patricie, Canivenc-Gansel, Elisabeth, Conzelmann, Andreas, Imhof, Isabella, Reggiori, Fulvio   +5 more
core  

Enrichment of phosphatidylinositols with specific acyl chains.

Biochimica et Biophysica Acta, 2014
Kenneth D'souza, R. Epand
semanticscholar   +1 more source

Prognostic Value of Lupus Anticoagulant and Anti–β2 Glycoprotein I Antibody in Adverse Pregnancy Outcomes

Arthritis &Rheumatology, EarlyView.
Objective International criteria for antiphospholipid syndrome (APS) include lupus anticoagulant (LA), anticardiolipin (aCL) IgG and IgM, and anti–β2‐glycoprotein I (β2GPI) IgG and IgM. However, evidence supporting their prognostic value or treatment efficacy in improving live birth rates is limited.
Megumi Nonobe, Takahiro Otani, Hiroyuki Yoshihara, Shinobu Goto, Tamao Kitaori, Naomi Nishikawa, Yuichiro Fujieda, Tatsuya Atsumi, Mayumi Sugiura‐Ogasawara   +8 more
wiley   +1 more source

Insulin Regulates Alternative Splicing of Protein Kinase C βII through a Phosphatidylinositol 3-Kinase-dependent Pathway Involving the Nuclear Serine/Arginine-rich Splicing Factor, SRp40, in Skeletal Muscle Cells [PDF]

, 2001
Niketa Patel, Charles E. Chalfant, James Watson, Jacqueline R. Wyatt, Nicholas M. Dean, Duane C. Eichler, Denise R. Cooper   +6 more
openalex   +1 more source

The structure, biosynthesis and function of glycosylated phosphatidylinositols in the parasitic protozoa and higher eukaryotes.

Biochemical Journal, 1993
M. McConville, M. Ferguson
semanticscholar   +1 more source

Identification of histone deacetylase inhibitor targeting type I interferon and B‐cell abnormalities in systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is characterized by increased type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama, Hachiro Konaka, Yasuhiro Kato, Takayuki Shibahara, Chisato Nishizawa, Kohei Tsujimoto, JeongHoon Park, Eri Itotagawa, Tatsunori Jo, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Wataru Aoki, Ken J Ishii, Hyota Takamatsu, Atsushi Kumanogoh   +16 more
wiley   +1 more source

Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors

, 2016
Makoto Nakakido, Kenji Tamura, Suyoun Chung, Koji Ueda, Risa Fujii, Kazuma Kiyotani, Yusuke Nakamura   +6 more
openalex   +2 more sources

IL-21 Promotes CD4 T Cell Responses by Phosphatidylinositol 3-Kinase–Dependent Upregulation of CD86 on B Cells [PDF]

, 2014
Kesley Attridge, Rupert Kenefeck, Lukasz Wardzinski, Omar Qureshi, Chun Jing Wang, Claire N. Manzotti, Klaus Okkenhaug, Lucy S. K. Walker   +7 more
openalex   +1 more source