Results 171 to 180 of about 73,691 (318)

Epirubicin Alters Pancreatic Autophagy and Insulin Synthesis Through a Zinc‐Dependent Mechanism

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Epirubicin (EPI) can cause metabolic side effects, including chemotherapy‐related diabetes, partly through oxidative stress that disrupts zinc (Zn) homeostasis and impairs autophagy. This study investigated the effects of EPI on Zn regulation and autophagy in the pancreas, as well as the modulatory role of N‐acetylcysteine (NAC). Rats received
Ebru Afşar, Işıl Eranıl
wiley   +1 more source

Metabolomic atlas of dengue virus infection reveals distinct circulating bioactive lipid signatures. [PDF]

open access: yesPLoS Negl Trop Dis
Anshad AR   +8 more
europepmc   +1 more source

Organizational and Functional Principles of the Obligate Respiratory Chain Supercomplex

open access: yesJournal of the Chinese Chemical Society, EarlyView.
In this review we deliver a comprehensive structural analysis of the actinobacterial respiratory chain supercomplex and discuss the principles underlying the assembly of its supramolecular architecture. ABSTRACT Proton translocating respiratory chain complexes assemble into supramolecular structures in their native cellular environment, yet the ...
Wei‐Chun Kao, Nick Hiatt, Carola Hunte
wiley   +1 more source

Human skeletal muscle disuse atrophy has profound and negative effects on the muscle metabolome and lipidome. [PDF]

open access: yesAm J Physiol Endocrinol Metab
Kilroe SP   +10 more
europepmc   +1 more source

The fatty acids in unremodelled trypanosome glycosyl-phosphatidylinositols.

open access: yesBiochemical Journal, 1994
T. Doering   +4 more
semanticscholar   +1 more source

Heavy Metal Mixture Exposure and Insulin Resistance in U.S. Adults: The Mediating Role of Systemic Inflammation

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
In a nationally representative sample of 3042 U.S. adults from NHANES 2021–2023, blood lead, cadmium, and mercury, both individually and as a weighted quantile sum (WQS) mixture, were inversely associated with insulin resistance assessed by HOMA‐IR. Systemic inflammation, measured by high‐sensitivity C‐reactive protein (hs‐CRP), significantly mediated ...
Cai Zhang, Shidi Lin, Yu Lin
wiley   +1 more source

TRAM-LAG1-CLN8 domain-containing protein TMEM56 regulates cell migration by changing intracellular ceramide levels. [PDF]

open access: yesBMC Biol
Dorschner B   +8 more
europepmc   +1 more source

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