Results 201 to 210 of about 73,691 (318)

Enterovirus infections in children

Pediatric Investigation, EarlyView.
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Xiangpeng Chen, Lingyun Guo, Xiaobo Lei, Linqing Zhao, Mingyan Hei, Jun Shen, Ju Yin, Fei Li, Jikui Deng, Gang Liu, Yong Zhang, Zhengde Xie   +11 more
wiley   +1 more source

Curcumin modulates hepatic pyroptosis-autophagy crosstalk induced by aflatoxin B1 via rumen microbiota-blood-liver axis. [PDF]

Microbiome
Liu T, Fan S, Li J, Wang T, Zhang J, Wang C.   +5 more
europepmc   +1 more source

Proteomic Profiling of Myofiber Repair Annexins and Their Role in Duchenne Muscular Dystrophy

PROTEOMICS, EarlyView.
ABSTRACT Myofiber regeneration and membrane repair play crucial roles in maintaining the continuous physiological functioning of the neuromuscular system. A swift and efficient repair mechanism enables the rapid restoration of sarcolemmal integrity following cellular impairment in damaged skeletal muscles.
Paul Dowling, Dounia Bouragba, Elisa Negroni, Capucine Trollet, Margit Zweyer, Dieter Swandulla, Kay Ohlendieck   +6 more
wiley   +1 more source

HIV-1 Tat-induced VAPB disruption initiates a cascade of organellar failures culminating in neuronal lipid accumulation. [PDF]

J Lipid Res
Santerre M, Arjona SP, Cai KQ, Shcherbik N, Sawaya BE.   +4 more
europepmc   +1 more source

Epigenetic Regulation of Liver Fibrosis: Mechanisms and Therapeutic Implications

Portal Hypertension &Cirrhosis, EarlyView.
This review synthesizes the epigenetic mechanisms—DNA methylation, histone modifications, and non‐coding RNAs—that drive hepatic stellate cell activation and the progression of liver fibrosis. It further evaluates emerging therapeutic strategies targeting these epigenetic regulators, including DNA methyltransferase and histone deacetylase inhibitors ...
Maryam Jadid Tavaf, Mahboobeh Ebrahimi Varkiani, Saeid Abroun, Pedram Asadi‐Sarabi, Shukoofeh Torabi, Elham Rismani, Mohammad Majd Hammour, Andreas K. Nüssler, Massoud Vosough   +8 more
wiley   +1 more source

Lipidomic Profile of Individuals Infected by <i>Schistosoma mansoni</i>. [PDF]

Int J Mol Sci
Fialho TRS, Dos Santos RA, Tabajara Y, Casaes AC, Macedo MN, Souza BOL, de Jesus KEM, Farias LP, Menezes CA, de Siqueira IC, Sorgi CA, Queiroz A, Oliveira RR.   +12 more
europepmc   +1 more source

Genomic insights into the local adaptation of spontaneous olive trees in the Mediterranean Basin highlight the need for conservation planning in the face of global change

PLANTS, PEOPLE, PLANET, EarlyView.
The Mediterranean Basin, a major biodiversity hotspot, is highly vulnerable to climate and global changes. Wild olive trees form an essential part of this landscape and hold strong ecological, cultural and socio‐economic significance. By examining how these trees responded to past climatic conditions, this study shows adaptation of olive trees to local
Lison Zunino, Gautier Sarah, Lorenzo Rocchetti, Bénédicte Rhoné, Alexandre Soriano, Gaëtan Droc, Pierre Mournet, Ahmed El Bakkali, Evelyne Costes, Bouchaib Khadari, Philippe Cubry   +10 more
wiley   +1 more source

Response of Psychrotolerant Fungus <i>Mucor flavus</i> to Cell Wall Stress, Induced by Azo Dyes. [PDF]

Int J Mol Sci
Saharova SA, Ianutsevich EA, Danilova OA, Kochkina GA, Tereshina VM.   +4 more
europepmc   +1 more source

Evidence for substrate-cycling of 3-, 3,4-, 4-, and 4,5-phosphorylated phosphatidylinositols in plants.

Biochemical Journal, 1995
C. Brearley, D. Hanke
semanticscholar   +1 more source

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva, Monique Mantovani, Maria E. S. D. Lino, Aline O. Albuquerque, João H. M. da Silva, Ronaldo A. P. Nagem, Adriana L. Rojas, Geraldo R. Sartori, Eduardo Horjales, David Campbell, Otavio H. Thiemann   +10 more
wiley   +1 more source