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Specificity of Acyl Chain Composition of Phosphatidylinositols

Proteomics, 2019
Phosphatidylinositol (PI) lipids have a predominance of a single molecular species present through the organism. In healthy mammals this molecular species is 1‐stearoyl‐2‐arachidonoyl (18:0/20:4) PI.
J. Bozelli, R. Epand
semanticscholar   +1 more source

Modulation of phosphatidylinositol turnover by liposomes containing phosphatidylinositol

1987
Publisher Summary This chapter discusses the methods for preparing liposomes for coating (opsonizing) the liposomes with immunoglobulin M (IgM) antibodies and complement or opsonizing with concanavalin A (Con A) to promote phagocytosis and resulting increased phosphatidylinositol (PI) turnover, for obtaining and culturing mouse peritoneal macrophages,
N M, Wassef, C R, Alving
openaire   +2 more sources

Oncogenes and Phosphatidylinositol Turnover

Annals of the New York Academy of Sciences, 1986
Products of phosphatidylinositol turnover have recently been implicated as regulators of cell growth and differentiation. Transformation of cells in culture by infection with certain viruses (Rous sarcoma virus, Kirsten sarcoma virus, and polyoma virus) or by transfection with the oncogenes carried by these viruses affect the steady-state level of ...
L C, Cantley   +6 more
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Trafficking of phosphatidylinositol by phosphatidylinositol transfer proteins

Biochemical Society Symposia, 2007
PtdIns is synthesized at the endoplasmic reticulum and its intracellular distribution to other organelles can be facilitated by lipid transfer proteins [PITPs (phosphatidylinositol transfer proteins)]. In this review, I summarize the current understanding of how PITPs are regulated by phosphorylation, how can they dock to membranes to exchange their ...
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Phosphatidylinositol signalling reactions

Seminars in Cell & Developmental Biology, 1998
Phosphatidylinositols are important in intracellular signaling. In response to extracellular signals, these molecules undergo rapid turnover and generate second messengers including diacylglycerol, inositol 1,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate (PtdIns 3,4P2) and phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3).
X, Zhang, P W, Majerus
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Phosphatidylinositol 3‐kinase

BioEssays, 1994
AbstractCurrently, a central question in biology is how signals from the cell surface modulate intracellular processes. In recent years phosphoinositides have been shown to play a key role in signal transduction. Two phosphoinositide pathways have been characterized, to date.
R, Kapeller, L C, Cantley
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