Results 231 to 240 of about 22,548 (354)

Biomarkers in Hereditary Spastic Paraplegias. [PDF]

Int J Mol Sci
Panza E, Orlacchio A.
europepmc   +1 more source

Noise‐Induced Hearing Loss: From Pathological Mechanisms to Therapeutic Interventions

Sensory Neuroscience, EarlyView.
ABSTRACT Noise‐induced hearing loss (NIHL), a significant non‐genetic form of hearing impairment, is primarily managed through the use of hearing aids and cochlear implants. However, the fundamental pathological mechanisms underlying NIHL remain inadequately addressed.
Shiqi Huang, Yu Xiao, Jiaxin Liu, Wen Jiang, Weiwei Shi, Hanbing Zhang, Xiaolong Fu, Yunhao Wu   +7 more
wiley   +1 more source

Cathepsin B-Responsive Phosphatidylinositol 3-Kinase (PI3K) Prodrug for the Treatment of Pulmonary Fibrosis

Xin Li, Tao Yang, Shuyue Lei, Xing Jiang, Shulei Zhu, Xuzhuo Li, Mengyuan Ding, Wei Tang, Wei Lu   +8 more
openalex   +2 more sources

Intestinal Sugar Absorption Is Regulated by Phosphorylation and Turnover of Protein Kinase C βII Mediated by Phosphatidylinositol 3-Kinase- and Mammalian Target of Rapamycin-dependent Pathways [PDF]

, 2003
Philip A. Helliwell, Martin G. Rumsby, George L. Kellett   +2 more
openalex   +1 more source

Innovative Application of a Multifunctional Sucrose-Gelatin Hydrogel Matrix in Desorption Electrospray Ionization-Mass Spectrometry Imaging. [PDF]

Anal Chem
Ziaco M, Vitale GA, Barra G, Marfella B, dell'Isola M, Albiani F, Grazioso A, Giamundo G, Nuzzo G, Manzo E, Gallo C, Castiglia D, Verrillo L, Miano MG, Cristino L, Conte I, d'Ippolito G, Fontana A.   +17 more
europepmc   +1 more source

Dietary Phosphatidylinositol [PDF]

, 2020
openaire   +1 more source

Mechanistic Insight Into Ionizable Cationic Lipid‐Mediated Endosomal Escape via Transient Lipid Complexes

Small, EarlyView.
Coarse‐grained simulations show that the formation of transient anionic–cationic lipid pairs regulates the rate‐limiting step for the lamellar‐to‐hexagonal phase transition in mixtures of anionic and cationic lipids mimicking the endosomal membrane after fusion with lipid‐based nanoparticles, thus playing an important role in the endosomal escape of ...
David Noel Zimmer, Friederike Schmid, Giovanni Settanni   +2 more
wiley   +1 more source

Understanding lipidomics associations and the lipoprotein-related caveats in population epidemiology. [PDF]

Am J Epidemiol
Zhao S, Ohukainen P, Kettunen J, Järvelin MR, Kähönen M, Lehtimäki T, Viikari J, Raitakari OT, Mäkinen VP, Ala-Korpela M.   +9 more
europepmc   +1 more source

Phosphatidylinositol-Antikörper [PDF]

, 2019
openaire   +1 more source

Tributyltin Protumorigenic Effects Targeting Prostate Cancer Cell Metabolism, Proliferation, Migration, and Invasion

Environmental Toxicology, EarlyView.
ABSTRACT Prostate cancer (PCa) is an endocrine‐related cancer highly dependent on androgenic signaling. Beyond hormone dependence, extrinsic factors play a significant role in the risk of developing PCa, which raises concern about the influence of environmental compounds such as endocrine‐disrupting chemicals (EDCs). Tributyltin (TBT) is an EDC used in
Mariana Feijó, Luís P. Brás, Catarina M. D. Serra, Lara R. S. Fonseca, Sara Correia, Bruno J. Pereira, Ana P. Duarte, Henrique J. Cardoso, Cátia V. Vaz, Sílvia Socorro   +9 more
wiley   +1 more source