Results 221 to 230 of about 22,548 (354)

Cytokine-stimulated T cells induce macrophage IL-10 production dependent on phosphatidylinositol 3-kinase and p70S6K: implications for rheumatoid arthritis [PDF]

, 2001
Andrew Foey, Patricia Green, Brian M. J. Foxwell, Marc Feldmann, Fionula M. Brennan   +4 more
openalex   +1 more source

Editorial: Exploring 'omic' biomarkers in animal production and reproduction. [PDF]

Front Vet Sci
Aponte PM, Gutiérrez-Reinoso MA, García-Herreros M.   +2 more
europepmc   +1 more source

Epigallocatechin‐3‐Gallate Suppresses Glioma by Targeting Integrin αvβ3/FAK/ERK Signaling Axis and Matrix Metalloproteinases

Phytotherapy Research, EarlyView.
EGCG suppresses glioma progression by targeting integrin αvβ3/FAK/ERK signaling and inhibiting MMP‐2/MMP‐9‐mediated ECM degradation, thereby blocking proliferation, migration, invasion, and promoting apoptosis. ABSTRACT Epigallocatechin‐3‐gallate (EGCG), the most abundant and biologically active catechin in green tea, has been widely reported to ...
Rui Sun, Yonghan Pan, Ning Yang, Bing Kang, Hong Xiao, Xianglong Tang, Taiping Li, Mengjie Zhao   +7 more
wiley   +1 more source

Structural basis for metalloprotein catalysis : Characterization of Mycobacterium tuberculosis phosphatidylinositol phosphate synthase PgsA1 and Bacillus anthracis ribonucleotide reductase R2

, 2020
K. Grave
openalex   +1 more source

Retinoblastoma gene‐independent G₁ phase arrest by flavone, phosphatidylinositol 3‐kinase inhibitor, and histone deacetylase inhibitor [PDF]

, 2012
Mitsuhiro Tomosugi, Yoshihiro Sowa, Shusuke Yasuda, Ryoichi Tanaka, Hein te Riele, Haruna Ikawa, Makoto Koyama, Toshiyuki Sakai   +7 more
openalex   +1 more source

A Combined Colon Organoid‐Sensory Neuron Model Reveals Epithelial Contribution to Moringin Efficacy Against Painful Inflammatory Bowel Disease

Phytotherapy Research, EarlyView.
Experimental workflow and main findings of the study. ABSTRACT Visceral pain is a major symptom of inflammatory bowel diseases (IBDs), requiring effective treatment strategies. Gut epithelium, beyond maintaining barrier integrity and microbiota homeostasis, modulates neurosensorial circuitries, influencing visceral sensitivity.
Francesco Margiotta, Elena Lucarini, Alessandra Toti, Maria Giovanna Cataldi, Clara Ciampi, Gina Rosalinda De Nicola, Lorenzo Di Cesare Mannelli, Carla Ghelardini   +7 more
wiley   +1 more source

Reduced lipid metabolite abundance in human pancreatic cancer and matched serum samples following neoadjuvant FOLFIRINOX treatment. [PDF]

Metabolomics
Amrutkar M, Guttorm SJT, Labori KJ, Rootwelt H, Elgstøen KBP, Gladhaug IP, Verbeke CS.   +6 more
europepmc   +1 more source

Novel Therapeutics for Chronic Obstructive Pulmonary Disease: From Empirical Bronchodilation to Precision Medicine

Respirology, EarlyView.
ABSTRACT Chronic obstructive pulmonary disease (COPD) remains the third leading cause of death worldwide, and conventional bronchodilator‐based therapies have limited efficacy in preventing exacerbations and disease progression. The 2024–2026 period represents a historic inflection point: three mechanistically distinct agents received Food and Drug ...
Naoya Fujino, Hisatoshi Sugiura
wiley   +1 more source

Additional file 7 of Evolutionary history of phosphatidylinositol- 3-kinases: ancestral origin in eukaryotes and complex duplication patterns

, 2015
Héloïse Philippon, Céline Brochier-Armanet, Guy Perrière   +2 more
openalex   +1 more source

Insulin Regulates Alternative Splicing of Protein Kinase C βII through a Phosphatidylinositol 3-Kinase-dependent Pathway Involving the Nuclear Serine/Arginine-rich Splicing Factor, SRp40, in Skeletal Muscle Cells [PDF]

, 2001
Niketa Patel, Charles E. Chalfant, James Watson, Jacqueline R. Wyatt, Nicholas M. Dean, Duane C. Eichler, Denise R. Cooper   +6 more
openalex   +1 more source