Results 321 to 330 of about 77,486 (386)

The Lipid Composition of the Exo-Metabolome from <i>Haemonchus contortus</i>. [PDF]

open access: yesMetabolites
Godoy P   +4 more
europepmc   +1 more source

A novel protein encoded by porcine circANKRD17 activates the PPAR pathway to regulate intramuscular fat metabolism. [PDF]

open access: yesJ Anim Sci Biotechnol
He X   +8 more
europepmc   +1 more source

The impact of Foxp3+ regulatory T‐cells on CD8+ T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley   +1 more source

Improvement of high-density lipoprotein atheroprotective properties in patients with systemic lupus erythematosus after belimumab treatment. [PDF]

open access: yesRheumatology (Oxford)
Dedemadi AG   +12 more
europepmc   +1 more source

Arrestin‐centred interactions at the membrane and their conformational determinants

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract More than 30 years after their discovery, arrestins are recognised multiprotein scaffolds that play essential roles in G protein‐coupled receptor (GPCR) regulation and signalling. Originally named for their capacity to hinder GPCR coupling to G proteins and facilitate receptor desensitisation, arrestins have emerged as key hubs for a myriad of
Owen Underwood   +3 more
wiley   +1 more source

Commercially Available Blue Diode Laser Engraver Operating at 455 nm as an Affordable LD-REIMS Ionization Source. [PDF]

open access: yesAnal Chem
Weider P   +6 more
europepmc   +1 more source

G protein‐coupled receptor‐mediated autophagy in health and disease

open access: yesBritish Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) constitute the largest and most diverse superfamily of mammalian transmembrane proteins. These receptors are involved in a wide range of physiological functions and are targets for more than a third of available drugs in the market. Autophagy is a cellular process involved in degrading damaged proteins and organelles
Devrim Öz‐Arslan   +2 more
wiley   +1 more source

ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system

open access: yesBritish Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison   +15 more
wiley   +1 more source

Relationship between Plasma Lipid Profile and Cognitive Status in Early Alzheimer Disease. [PDF]

open access: yesInt J Mol Sci
Peña-Bautista C   +8 more
europepmc   +1 more source

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