Results 1 to 10 of about 8,623 (288)

Feasibility of the preparation of cochleate suspensions from naturally derived phosphatidylserines [PDF]

Frontiers in Medical Technology, 2023
IntroductionCochleates are cylindrical particles composed of dehydrated phospholipid bilayers. They are typically prepared by addition of calcium ions to vesicles composed of negatively charged phospholipids such as phosphatidylserines (PS). Due to their
Søren Kristensen, Khadeija Hassan, Nadia Skarnager Andersen, Frank Steiniger, Judith Kuntsche   +4 more
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Methyl carbamates of phosphatidylethanolamines and phosphatidylserines reveal bacterial contamination in mitochondrial lipid extracts of mouse embryonic fibroblasts [PDF]

Scientific Reports, 2023
The occurrence of methyl carbamates of phosphatidylethanolamines and phosphatidylserines in the lipid extract of mitochondria obtained from mouse embryonic fibroblasts was ascertained by hydrophilic interaction liquid chromatography with electrospray ...
Andrea Castellaneta, Vito Porcelli, Ilario Losito, Serena Barile, Alessandra Maresca, Valentina Del Dotto, Ludovica Sofia Guadalupi, Cosima Damiana Calvano, Valerio Carelli, Luigi Palmieri, Tommaso R. I. Cataldi   +10 more
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Plasma Lipidomic Alterations in Fontan Circulation Reflect Cardiovascular Functional Reserve [PDF]

Metabolites
Background: Fontan circulation is associated with impaired cardiac output, reduced exercise capacity, and systemic metabolic stress. However, the underlying lipidomic alterations remain poorly defined.
Arun Surendran, Amir Ravandi, Ashish H. Shah   +2 more
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Multi-Omic Characterization of Epithelial–Mesenchymal Transition: Lipidomic and Metabolomic Profiles as Key Markers of TGF-β-Induced Transition in Huh7 Hepatocellular Carcinoma [PDF]

Cells
Epithelial–mesenchymal transition (EMT) is a key process in cancer progression and fibrogenesis. In this study, EMT was induced in Huh7 hepatocellular carcinoma cells via TGF-β1 treatment, and the resulting lipidomic and metabolomic alterations were ...
Agnese Bertoldi, Gaia Cusumano, Eleonora Calzoni, Husam B. R. Alabed, Roberto Maria Pellegrino, Sandra Buratta, Lorena Urbanelli, Carla Emiliani   +7 more
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A Japanese Case of Lenz‐Majewski Syndrome With a Novel PTDSS1 Variant [PDF]

Molecular Genetics & Genomic Medicine
Background Lenz‐Majewski syndrome (LMS) is a rare genetic disorder characterized by osteosclerosis, intellectual disability, characteristic facies, and distinct craniofacial, dental, cutaneous, and distal‐limb anomalies.
Yasuko Kobari, Non Miyata, Jun Takayama, Naoya Saijo, Tomohisa Suzuki, Shigeo Kure, Atsuo Kikuchi, Gen Tamiya, Takumi Takizawa   +8 more
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Variations in the milk lipidomic profile of lactating dairy cows fed the diets containing alfalfa hay versus alfalfa silage [PDF]

Animal Nutrition
Alfalfa is primarily stored as silage or hay in livestock production. Previous research has shown that the storage method of grass significantly influences milk composition.
Kaizhen Liu, Meiqing Chen, Guoxin Huang, Chuanyou Su, Wenhao Tang, Ning Li, Jiyong Yang, Xufang Wu, Boxue Si, Shengguo Zhao, Nan Zheng, Yangdong Zhang, Jiaqi Wang   +12 more
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Angiotensin II Alters Mitochondrial Membrane Potential and Lipid Metabolism in Rat Colonic Epithelial Cells [PDF]

Biomolecules
An over-active renin-angiotensin system (RAS) is characterized by elevated angiotensin II (Ang II). While Ang II can promote metabolic and mitochondrial dysfunction in tissues, little is known about its role in the gastrointestinal system (GI).
Darby D. Toth, Christopher L. Souder, Sarah Patuel, Cole D. English, Isaac Konig, Emma Ivantsova, Wendi Malphurs, Jacqueline Watkins, Kaylie Anne Costa, John A. Bowden, Jasenka Zubcevic, Christopher J. Martyniuk   +11 more
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Characterization of the Lipidome and Biophysical Properties of Membranes from High Five Insect Cells Expressing Mouse P-Glycoprotein

Biomolecules, 2021
The lipid composition of biomembranes influences the properties of the lipid bilayer and that of the proteins. In this study, the lipidome and the lipid/protein ratio of membranes from High Five™ insect cells overexpressing mouse P-glycoprotein was ...
Maria João Moreno, Patrícia Alexandra Teles Martins, Eva F. Bernardino, Biebele Abel, Suresh V. Ambudkar   +4 more
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Decreased Hyocholic Acid and Lysophosphatidylcholine Induce Elevated Blood Glucose in a Transgenic Porcine Model of Metabolic Disease

Metabolites, 2022
(1) Background: This work aims to investigate the metabolomic changes in PIGinH11 pigs and investigate differential compounds as potential therapeutic targets for metabolic diseases.
Jianping Xu, Kaiyi Zhang, Bintao Qiu, Jieying Liu, Xiaoyu Liu, Shulin Yang, Xinhua Xiao   +6 more
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Plasma procoagulant phospholipid clotting time and venous thromboembolism risk

Research and Practice in Thrombosis and Haemostasis, 2021
Background Negatively charged procoagulant phospholipids, phosphatidylserine (PS) in particular, are vital to coagulation and expressed on the surface membrane of extracellular vesicles.
Cathrine Ramberg, Line Wilsgård, Nadezhda Latysheva, Sigrid K. Brækkan, Kristian Hindberg, Timofey Sovershaev, Omri Snir, John‐Bjarne Hansen   +7 more
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