Results 111 to 120 of about 8,775 (288)

Phosphatidylserine flipping enhances membrane curvature and negative charge required for vesicular transport [PDF]

, 2013
Peng Xu, Ryan D. Baldridge, J. Richard, Christopher G. Burd, Todd R. Graham   +4 more
openalex   +1 more source

Chemotherapeutic Potential of Fluorouracil‐Platinum (IV) Prodrugs Against Cisplatin‐Resistant Colorectal Cancer Cells

Chemistry – A European Journal, EarlyView.
ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias, Aleen Khoury, Shadma Fatima, Timothy J. Mann, Shawan Karan, Meena Mikhael, Paul de Souza, Christopher P. Gordon, Kieran F. Scott, Janice R. Aldrich‐Wright   +9 more
wiley   +1 more source

Anti-Phosphatidylserine/Prothrombin Antibodies Are Associated with Adverse Pregnancy Outcomes [PDF]

, 2015
Polona Žigon, Katja Perdan Pirkmajer, Matija Tomšič, Tanja Kveder, Borut Božič, Snežna Sodin Šemrl, Saša Čučnik, Aleš Ambrožič   +7 more
openalex   +1 more source

Carbon Dots for Cancer Theranostics: Synthesis Strategies, Luminescence Properties, and Advances in Bioimaging‐Guided Diagnosis and Therapy

Chemistry – A European Journal, EarlyView.
Lighting up the path to precision oncology: This review comprehensively summarizes the rational design of carbon dots (CDs), elucidating how core size, surface chemistry, and heteroatom doping dictate their luminescence mechanisms. Special emphasis is placed on engineering NIR‐II emissive CDs for deep‐tissue imaging.
Zekun Yan, Yupeng Liu, Jinyun Tan, Songnan Qu   +3 more
wiley   +1 more source

The Obligate Intracellular Parasite Toxoplasma gondii Secretes a Soluble Phosphatidylserine Decarboxylase [PDF]

, 2012
Nishith Gupta, Anne Hartmann, Richard Lucius, Dennis R. Voelker   +3 more
openalex   +1 more source

Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical Prospects

Cancer Nexus, EarlyView.
ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han, Ying Wang, Xintao Gao, Yan Lei, Yantao Li, Zhiyong Tang   +5 more
wiley   +1 more source

A New High-Temperature Transition of Crystalline Cholesterol in Mixtures with Phosphatidylserine [PDF]

, 2001
Richard M. Epand, D. Bach, Raquel F. Epand, Nina Borochov, Ellen Wachtel, Nina Borochov, Ellen Wachtel   +6 more
openalex   +1 more source

B1-cell-produced anti-phosphatidylserine antibodies contribute to lupus nephritis development via TLR-mediated Syk activation [PDF]

, 2023
Kongyang Ma, Wenhan Du, Shiyun Wang, Fan Xiao, Jingyi Li, Jie Tian, Yida Xing, Xiaodan Kong, Ke Rui, Rencai Qin, Xiaoxia Zhu, Jing Wang, Cainan Luo, Haijing Wu, Yun Zhang, Chengping Wen, Lan He, Dongzhou Liu, Hejian Zou, Qianjin Lu, Lijun Wu, Liwei Lu   +21 more
openalex   +1 more source

Pss knockdown in the midgut causes growth retardation in Drosophila similar to that in human LMHD

Developmental Dynamics, EarlyView.
Abstract Background Phosphatidylserine synthase (PSS), localized in the mitochondrial membrane, synthesizes phosphatidylserine. In humans, mutations in Pss lead to Lenz–Majewski hyperostotic dwarfism, a disorder affecting growth and development. The effects of Pss mutations on the growth of Drosophila melanogaster are not fully known. Hence, this study
Kwan‐Young Kim, You‐Lim Hwang, Sunwoo Yeom, Seung‐Hae Kwon, Sang‐Hak Jeon   +4 more
wiley   +1 more source

Biological age as estimated by baseline circulating metabolites is associated with incident diabetes and mortality

The Journal of Nutrition, Health and Aging
Objectives: It is unclear how metabolomic assessment of biological aging performs in non-White populations and whether such an approach can predict future mortality.
La-or Chailurkit, Nisakron Thongmung, Prin Vathesatogkit, Piyamitr Sritara, Boonsong Ongphiphadhanakul   +4 more
doaj   +1 more source