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CARDIOPROTECTIVE EFFECTS OF PHOSPHOCREATINE

Вестник анестезиологии и реаниматологии, 2018
Goal of the review: to review theoretical and practical aspects of using exogenous phosphocreatine in the patients with cardio-vascular disorders in various clinical situations, given that phospho-transporting system disorders are the one of pathogenic ...
V. V. Lomivorotov, M. N. Abubakirov, E. V. Fominskiy, V. A. Shmyrev   +3 more
doaj   +2 more sources

The metabolites for muscle and osteoclast activity are indicators of femoral neck osteoporosis [PDF]

Scientific Reports
Femoral neck osteoporosis is a critical risk factor for a bedbound state, which significantly decreases overall life expectancy, if a patient falls and suffers a fracture.
Masahiro Kameda, Mitsuhiro Yanagida, Hiroshi Kondoh   +2 more
doaj   +2 more sources

Artificial mitochondria ameliorates osteoarthritis through restoring cellular energy metabolism homeostasis [PDF]

Bioactive Materials
Mitochondrial dysfunction under pathological or aging conditions disrupts adenosine triphosphate (ATP) synthesis, exacerbating disease progression by skewing energy metabolism toward catabolism.
Wenqiang Yan, Yu Chen, Haoda Wu, Zeyuan Gao, Xiaoqing Hu, Yingfang Ao, Chun Mao, Mimi Wan   +7 more
doaj   +2 more sources

Fusogenic Liposomes for the Intracellular Delivery of Phosphocreatine

Pharmaceuticals
Background/Objective: Maintaining intracellular adenosine triphosphate (ATP) levels is essential for numerous cellular functions, including energy metabolism, muscle contraction, and nerve impulse transmission.
Okhil K. Nag, Eunkeu Oh, James B. Delehanty   +2 more
doaj   +3 more sources

The effects of phosphocreatine disodium salts plus blueberry extract supplementation on muscular strength, power, and endurance

Journal of the International Society of Sports Nutrition, 2021
Background Numerous studies have demonstrated the efficacy of creatine supplementation for improvements in exercise performance. Few studies, however, have examined the effects of phosphocreatine supplementation on exercise performance.
John Paul V. Anders, Tyler J. Neltner, Robert W. Smith, Joshua L. Keller, Terry J. Housh, F. Joseph Daugherty, Michael S. Tempesta, Alekha K. Dash, Daniel J. Munt, Richard J. Schmidt, Glen O. Johnson   +10 more
doaj   +1 more source

Cardiovascular diseases and energy deficiency: pathogenetic ways of correction

Медицина неотложных состояний, 2023
Cardiovascular disease remains one of the most common and influential causes of death worldwide, as the heart plays a key role in the human body. Energetic cardioprotective therapy of the myocardium is an important protective factor, regulating the ...
M.S. Cherska, H.M. Kukharchuk
doaj   +1 more source

Pros and Cons of Two Methods of Anaerobic Alactic Energy Assessment in a High-Intensity CrossFit^® Workout

Oxygen, 2022
The current study aimed to evidence the strengths and weaknesses of two indirect methods for assessing the anaerobic alactic contribution to a specific CrossFit® workout.
Manoel Rios, Victor Machado Reis, Susana Soares, Daniel Moreira-Gonçalves, Ricardo J. Fernandes   +4 more
doaj   +1 more source

Nosological features of myocardial injury: an overview of the symposium

Лечащий Врач, 2021
The main theme of the symposium «Nosological features of myocardial injury: how to recognize and what to do?» became cardioprotective therapy and the use of safe and highly effective metabolically active drugs for energy support of the myocardium.
E. O. Girutskaya
doaj   +1 more source

Use of exogenic phosphocreatine in ICU rehabilitation of patients with COVID-19 (pilot study)

Вестник анестезиологии и реаниматологии, 2022
The objective: to establish the possible effectiveness of exogenous phosphocreatine as a component of pharmacological support during the resuscitation stage of rehabilitation measures in critically ill patients with COVID-19.Subjects and Methods.
D. А. Krapivina, S. V. Voevodin, А. V. Chernyak, E. V. Grigoriev   +3 more
doaj   +1 more source

Development of Triiodothyronine Polymeric Nanoparticles for Targeted Delivery in the Cardioprotection against Ischemic Insult

Biomedicines, 2021
Ischemic heart disease is the main cause of death globally. Cardioprotection is the process whereby mechanisms that reduce myocardial damage, and activate protective factors, contribute to the preservation of the heart. Targeting these processes could be
Ozlem Ozen Karakus, Noureldien H. E. Darwish, Thangirala Sudha, Taher A. Salaheldin, Kazutoshi Fujioka, Peter C. Taylor Dickinson, Brian Weil, Shaker A. Mousa   +7 more
doaj   +1 more source