Results 91 to 100 of about 48,855 (331)
Effects of Phosphocreatine on Apoptosis in a Cell-free System [PDF]
Journal of Biological Chemistry, 2001 The characteristic morphological and biochemical changes during caspase-mediated apoptosis can be reproduced to a large extent in a Xenopus laevis egg extract cell-free system by addition of mouse liver nuclei and exogenous cytochrome c. We show that in this system phosphocreatine accelerated the apoptotic morphological changes of the nuclei, but ...
Zhonghe Zhai +5 more
openaire +3 more sources
Glia, EarlyView.Cell culture studies show disrupted astrocyte physiology in the leukodystrophy MLC. Are intact astrocytes similarly affected? This study on astrocytes in MLC mouse brain slices confirms and extends in vitro studies on altered astrocyte physiology. ABSTRACT Electrical signaling, driven by ion fluxes between intra‐ and extracellular compartments, is ...
Sven Kerst +5 more
wiley +1 more source
Effects of reduced-volume of sprint interval training and the time course of physiological and performance adaptations [PDF]
, 2017 This study sought to determine the time course of training adaptations to two different sprint interval training programmes with the same sprint: rest ratio (1:8) but different sprint duration.
Babraj, J., Yamagishi, Takaki
core +1 more source
Journal of the International Society of Sports Nutrition, 2012 Background Exacerbated oxidative stress is thought to be a mediator of arterial hypertension. It has been postulated that creatine (Cr) could act as an antioxidant agent preventing increased oxidative stress.
Alves Christiano RR +8 more
doaj +1 more source
iLABMED, EarlyView.We developed an on‐site detection platform for rapid detection of Mycobacterium tuberculosis complex (MTBC) based on the IS1081 gene. The platform utilizes real‐time multiplex recombinase polymerase amplification (mRPA) to achieve a reaction time of less than 30 min.
Xiaoyan Tan +5 more
wiley +1 more source
Serum creatine kinase isoenzymes in children with osteogenesis imperfecta [PDF]
, 2017 This study evaluates serum creatine kinase isoenzyme activity in children with osteogenesis imperfecta to determine its usefulness as a biochemical marker during treatment with bisphosphonate.
Celli, L +8 more
core +1 more source
Metabolic Response of the Immature Right Ventricle to Acute Pressure Overloading
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 BackgroundSurgical palliation or repair of complex congenital heart disease in early infancy can produce right ventricular (RV) pressure overload, often leading to acute hemodynamic decompensation.
Masaki Kajimoto +5 more
doaj +1 more source
High-energy phosphate transfer in human muscle: diffusion of phosphocreatine.
American Journal of Physiology - Cell Physiology, 2011 The creatine kinase (CK) reaction is central to muscle energetics, buffering ATP levels during periods of intense activity via consumption of phosphocreatine (PCr).
R. Gabr +4 more
semanticscholar +1 more source
Patient‐derived xenograft models in pan‐cancer: From bench to clinic
Interdisciplinary Medicine, EarlyView.Abstract Patient‐derived xenograft (PDX) models provide a robust preclinical platform that preserves the genetic and phenotypic heterogeneity of patient tumors while mirroring their tumor genetic characteristics, which retain malignant cells and the tumor pathological structure, making them valuable for studying tumor progression and developing ...
Jiatong Li +5 more
wiley +1 more source
Srs2 promotes synthesis-dependent strand annealing by disrupting DNA polymerase δ-extending D-loops. [PDF]
, 2017 Synthesis-dependent strand annealing (SDSA) is the preferred mode of homologous recombination in somatic cells leading to an obligatory non-crossover outcome, thus avoiding the potential for chromosomal rearrangements and loss of heterozygosity.
Ede, Christopher +8 more
core +3 more sources