Results 111 to 120 of about 26,828 (231)

Sprint‐interval training with post‐exercise blood flow restriction increases mitochondrial content and respiration

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The mechanisms underpinning improved maximal oxygen uptake following sprint interval training (SIT) with post‐exercise blood flow restriction (BFR), compared to SIT alone, remain unclear. This study examined the effects of 6 week SIT with (BFR; n = 12) or without (CON; n = 8) post‐exercise BFR on V̇O2peak${{\dot{V}}_{{{{\mathrm{O}
Donald L. Peden   +4 more
wiley   +1 more source

PHOSPHOCREATINE

open access: yesJournal of Biological Chemistry, 1929
Cyrus H. Fiske, Yellapragada Subbarow
openaire   +1 more source

Effect of Water Suppression and Metabolite Cycling on Quantification of 1H MRS Spectra in the Human Brain at 3 Tesla

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 2, Page 542-547, August 2026.
ABSTRACT Purpose This study investigates the effect of VAPOR water suppression and metabolite cycling on metabolite quantification and macromolecules in proton magnetic resonance spectroscopy. Methods Single‐voxel semi‐LASER spectra (TR/TE = 3000/28 ms) and metabolite‐nulled spectra (macromolecules) were acquired in five healthy subjects in the ...
Dinesh K. Deelchand   +1 more
wiley   +1 more source

Preclinical 1H MRS Study of a Porcine Model Shows Evidence and Mechanisms for Acute Neuronal Injury in Neonatal Cardiopulmonary Bypass (CPB) Surgery

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 2, Page 557-567, August 2026.
ABSTRACT Purpose Congenital heart disease affects 1% of US births, with some infants requiring cardiothoracic surgery under cardiopulmonary bypass (CPB). Optimal surgical parameters to minimize neuronal injury are unknown. We used serial 1H MRS in a neonatal CPB porcine model to assess acute neuronal damage and associated injury mechanisms.
Aaron Omon   +5 more
wiley   +1 more source

The Impact and Reliability of Tissue Segmentation on In Vivo Magnetic Resonance Spectroscopy Metabolite Quantification

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 2, Page 516-529, August 2026.
ABSTRACT Purpose Quantification of metabolite concentrations using MRS requires tissue‐dependent signal corrections. Accurate estimation of voxel tissue composition is therefore essential. Commonly used brain tissue segmentation tools differ in their algorithms and implementation, potentially introducing variability in MRS‐derived concentration ...
Jessica Archibald   +12 more
wiley   +1 more source

Recent Trends in Metabolomics by NMR Spectroscopy

open access: yesAngewandte Chemie, Volume 138, Issue 24, 8 June 2026.
AI tools were applied to analyze more than 5 000 publications indexed in Scopus (2018–2025), identifying key trends and research directions in NMR‐based metabolomics. The artificial intelligence‐assisted workflow classified papers into six main fields of application, human health, food and nutrition, veterinary science, plants, environment, and ...
Giorgio Di Paco   +6 more
wiley   +2 more sources

(Phospho)creatine: the reserve and merry-go-round of brain energetics

open access: yesNeural Regeneration Research, 2023
Hong-Ru Chen, Ton DeGrauw, Chia-Yi Kuan
doaj   +1 more source

Enhanced Quantitative Phosphocreatine MR Imaging of Skeletal Muscle Using a Global–Local Two‐Branch Deep Learning Model

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 2, Page 741-755, August 2026.
ABSTRACT Purpose Phosphocreatine (PCr) is an essential marker of muscle metabolism, and accurate quantification of its (fs) and its exchange rate (ksw) is essential for diagnosing various muscular and neuromuscular diseases. Although chemical exchange saturation transfer (CEST) MRI can detect the saturation transfer effect from PCr, quantification of ...
Malvika Viswanathan   +9 more
wiley   +1 more source

Neuroprotective Effects of Biosynthetic d‐Calcium Pantothenate and Cyanocobalamin Against MPTP‐Induced Parkinsonism via Microbiota Modulation, Metabolic Homeostasis Restoration, and Endoplasmic Reticulum Stress Inhibition

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
Biosynthetic D‐calcium pantothenate and cyanocobalamin alleviate MPTP‐induced Parkinsonism in mice by modulating gut microbiota, restoring metabolic homeostasis, and inhibiting Endoplasmic Reticulum Stress. ABSTRACT Vitamin B5 (VB5) and Vitamin B12 (VB12) are essential micronutrients widely distributed in functional foods, yet their neuroprotective ...
Yaru Chen   +6 more
wiley   +1 more source

In Situ pH Determination Using 1H‐MRS Acetate Chemical Shift for Noninvasive Postmortem Examinations

open access: yesNMR in Biomedicine, Volume 39, Issue 7, July 2026.
The chemical‐shift difference between acetate and myo‐inositol measured by MRS enables estimation of pH in the acidic range. Noninvasive pH assessment in forensic investigations is demonstrated in 58 cases and validated by measurements in extracted tissue.
Sabina Frese   +4 more
wiley   +1 more source

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