Results 101 to 110 of about 44,180 (297)

Cardiac protection with phosphocreatine: a meta-analysis

Interactive CardioVascular and Thoracic Surgery, 2016
Phosphocreatine (PCr) plays an important role in the energy metabolism of the heart and a decrease in its intracellular concentration results in alteration of myocardium energetics and work. We conducted a meta-analysis of all randomized and matched trials that compared PCr with placebo or standard treatment in patients with coronary artery disease or ...
LANDONI, GIOVANNI, ZANGRILLO, ALBERTO, Lomivorotov VV, Likhvantsev V, Ma J, De Simone F, Fominskiy E.   +6 more
openaire   +3 more sources

Enhanced Quantitative Phosphocreatine MR Imaging of Skeletal Muscle Using a Global–Local Two‐Branch Deep Learning Model

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Phosphocreatine (PCr) is an essential marker of muscle metabolism, and accurate quantification of its (fs) and its exchange rate (ksw) is essential for diagnosing various muscular and neuromuscular diseases. Although chemical exchange saturation transfer (CEST) MRI can detect the saturation transfer effect from PCr, quantification of ...
Malvika Viswanathan, Leqi Yin, Yashwant Kurmi, Shuyang Chai, Xiaoyu Jiang, Yuankai Huo, Junzhong Xu, Limin Chen, John C. Gore, Zhongliang Zu   +9 more
wiley   +1 more source

Role of the phosphocreatine system on energetic homeostasis in skeletal and cardiac muscles

Einstein (São Paulo)
Adenosine triphosphate is the present energy currency in the body, and is used in various cellular and indispensable processes for the maintenance of cell homeostasis.
Lucas Guimarães-Ferreira
doaj   +1 more source

Analysis of creatine kinase activity with evaluation of protein expression under the effect of heat and hydrogen peroxide [PDF]

The Ukrainian Biochemical Journal, 2015
Protein oxidation has detrimental effects on the brain functioning, which involves inhibition of the crucial enzyme, brain type creatine kinase (CKBB), responsible for the CK/phosphocreatine shuttle system. Here we demonstrate a susceptibility of CKBB to
A. D. Rakhmetov, Lee Sang Pil, L. I. Ostapchenko, Chae Ho Zoon   +3 more
doaj  

Imaging biochemistry: applications to breast cancer. [PDF]

, 2001
The use of magnetic resonance spectroscopy (MRS) to investigate breast tumour biochemistry in vivo is reviewed. To this end, results obtained both from patients in vivo and from tumour extracts and model systems are discussed.
Leach, MO, Ronen, SM
core   +1 more source

Characterization of Metabolic, Diffusion, and Perfusion Properties in GBM: Contrast-Enhancing versus Non-Enhancing Tumor. [PDF]

, 2017
BackgroundAlthough the contrast-enhancing (CE) lesion on T1-weighted MR images is widely used as a surrogate for glioblastoma (GBM), there are also non-enhancing regions of infiltrative tumor within the T2-weighted lesion, which elude radiologic ...
Autry, Adam, Cha, Soonmee, Chang, Susan M, Lupo, Janine M, Maleschlijski, Stojan, Molinaro, Annette M, Nelson, Sarah J, Phillips, Joanna J, Roy, Ritu   +8 more
core   +2 more sources

GABA+‐Edited Magnetic Resonance Spectroscopy Deep Learning Quality Assessment Framework

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Motivated by the need to improve GABA+‐edited magnetic resonance spectroscopy (MRS) quality, we developed a three‐module framework to improve transient averaging based on quality. We hypothesized that training a deep learning (DL) model to differentiate spectrum quality could improve transient averaging compared to traditional ...
Hanna Bugler, Roberto Souza, Ashley D. Harris   +2 more
wiley   +1 more source

The effectiveness of phosphocreatine cardioprotection during vascular surgery in high cardiac risk patients

Вестник анестезиологии и реаниматологии
The objective was to study the occurrence of perioperative cardiovascular complications (CVС) and clinical and laboratory cardioprotection signs in patients treated with phosphocreatine infusion in intraoperative period of vascular surgery.Materials and ...
I. A. Kozlov, D. A.. Sokolov, P. A. Lyuboshevsky   +2 more
doaj   +1 more source

Endurance training facilitates myoglobin desaturation during muscle contraction in rat skeletal muscle. [PDF]

, 2015
At onset of muscle contraction, myoglobin (Mb) immediately releases its bound O2 to the mitochondria. Accordingly, intracellular O2 tension (PmbO2) markedly declines in order to increase muscle O2 uptake (mVO2).
Furuichi, Yasuro, Hashimoto, Takeshi, Hojo, Tatsuya, Iwase, Satoshi, Izawa, Tetsuya, Jue, Thomas, Masuda, Kazumi, Ojino, Minoru, Takakura, Hisashi, Yamada, Tatsuya   +9 more
core   +1 more source

Faster and More Robust CK Reaction Rate Estimation at 3T Using Acquisition‐Weighted 31P Cardiac 1D‐MRSI With Compartment‐Based Reconstruction

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Quantification of the creatine kinase (CK) forward reaction rate (kf) in the human heart using phosphorus magnetic resonance spectroscopy is clinically important; however, it is limited by long acquisition times, operator subjectivity in analysis, and potential skeletal muscle contamination.
Aaron Axford, Iveta Pajanová, William D. Watson, Andrew C. Tyler, Roshan Xavier, Ferenc E. Mózes, Oliver J. Rider, Damian J. Tyler, Ladislav Valkovič   +8 more
wiley   +1 more source