Results 91 to 100 of about 31,996 (262)
Abstract Anorexia nervosa (AN) is a psychiatric disorder characterized by prolonged caloric restriction and skeletal muscle atrophy. Mitochondrial health is a key mediator of muscle function, yet the role of mitochondria during AN and following weight regain has not been investigated. The objective of this study was to evaluate mitochondrial capacities
Megan E. Rosa‐Caldwell +12 more
wiley +1 more source
Cardiac protection with phosphocreatine: a meta-analysis
Phosphocreatine (PCr) plays an important role in the energy metabolism of the heart and a decrease in its intracellular concentration results in alteration of myocardium energetics and work. We conducted a meta-analysis of all randomized and matched trials that compared PCr with placebo or standard treatment in patients with coronary artery disease or ...
LANDONI, GIOVANNI +6 more
openaire +3 more sources
Postexercise phosphocreatine resynthesis is slowed in multiple sclerosis
To determine whether skeletal muscle oxidative metabolism is impaired in multiple sclerosis (MS), 31 phosphorus magnetic resonance spectroscopy was used to measure the rate of intramuscular phosphocreatine (PCr) resynthesis following exercise in MS and ...
Robert G. Miller +7 more
core +1 more source
Role of the creatine/phosphocreatine system in the regulation of mitochondrial respiration.
International audienceThe mechanism of metabolic regulation of mitochondrial respiration in cardiac muscle cells was studied experimentally in the permeabilized heart fibres of mice and by computer modelling in silico.
Kongas, O. +3 more
core +1 more source
Background: Traumatic brain injury (TBI) is a global concern, and many people suffer from TBI annually. Determining the outcome of patients with brain injury has a valuable clinical impact and results in better management of patients.
Mohammad Ali Abouei Mehrizi +6 more
doaj +1 more source
Phosphocreatine Content of Mammalian Cardiac Muscle.
Summary1. “Resting” values for the phosphocreatine content of the ventricles of several mammalian species are reported and an explanation is offered for some of the low values recorded in the literature. The necessary precautions are noted if maximal values are to be obtained. 2.
G, FAWAZ, E S, HAWA
openaire +2 more sources
Phosphocreatine (PCr) recovery (normalised to resting values) in trained human calf muscle after dynamic exercise during two separate but identical tests. Values shown are means±SEM.
Kieran Clarke (88473) +7 more
core +1 more source
Abstract The purpose was to test: (1) whether the decline in maximal motor unit (MU) firing rate is an invariable response when maximal voluntary contraction (MVC) torque is reduced following a submaximal muscle fatiguing task; and (2) whether fatigue‐induced slowing of contractile speed and firing rate decline are co‐dependent. Ten participants (three
Alexander M. Zero +3 more
wiley +1 more source
Neuroprotective mechanisms of creatine occur in the absence of mitochondrial creatine kinase
There is substantial evidence that creatine administration exerts neuroprotective effects both in vitro and in vivo. The precise mechanisms for these neuroprotective effects however are as yet unclear.
Peter Klivenyi +7 more
doaj +1 more source
A linear model of muscle respiration explains monoexponential phosphocreatine changes
Phosphocreatine (PCr) content was measured by phosphorus nuclear magnetic resonance spectroscopy in the gastrocnemius muscles of pentobarbital-anesthetized rats during and after twitch stimulation at rates up to 0.75 Hz. The monoexponential time constant
R. A. Meyer
core +1 more source

