Creatine kinase B mediates UCP1-independent beige fat thermogenesis via the futile creatine cycle in mice. [PDF]
Bunk J +6 more
europepmc +1 more source
High-energy phosphate transfer in human muscle: diffusion of phosphocreatine.
R. Gabr +4 more
semanticscholar +1 more source
Magnetic Resonance Spectroscopy of Cystathionine and 2‐Hydroxyglutarate in Brain Tumors
Cystathionine and 2‐hydroxyglutarate were evaluated in 38 glioma patients with TE 97ms PRESS at 3T. Cystathionine level was significantly higher in IDH‐mutant 1p/19q‐codeleted gliomas than in IDH‐mutant non‐codeleted gliomas (p = 0.002). The sensitivity and specificity of the cystathionine measures with respect to 1p/19q status were 0.8 and 0.79, while
Changho Choi +17 more
wiley +1 more source
<sup>1</sup>H and <sup>31</sup>P MRS Interleaved With High Time Resolution Reveals Closely Matching Creatine CH₂ and PCr Dynamics During Exercise. [PDF]
Klepochová R +8 more
europepmc +1 more source
Cost-Effectiveness Analysis of Standard Therapy with Phosphocreatine VS Standard Therapy In Perioperative Management of Cardiac Surgery Patients With Extracorporeal Circulation, With Ischemic Heart Disease or With Chronic Heart Insufficiency [PDF]
R.I. Yagudinа +2 more
openalex +1 more source
Gradient Scheme Optimization for PRESS‐Localized Edited MRS Using Weighted Pathway Suppression
This study presents an optimized DOTCOPS‐based gradient scheme for PRESS‐localized edited MRS that integrates a volume‐based likelihood model to prioritize suppression of unwanted coherence transfer pathways. Using a dual‐penalty genetic algorithm, the scheme achieved a 197% increase in k‐space crushing efficiency and significantly reduced out‐of‐voxel
Gizeaddis L. Simegn +11 more
wiley +1 more source
Patterns of altered in vivo brain metabolism in patients with amyotrophic lateral sclerosis (ALS) and asymptomatic C9orf72 mutation carriers: a cross-sectional <sup>1</sup>H and <sup>31</sup>P magnetic resonance spectroscopic 7T imaging study. [PDF]
Westeneng HJ +12 more
europepmc +1 more source
Deuterium metabolic imaging (DMI) is a novel metabolic imaging technique where 2H MRSI is combined with the administration of 2H‐labeled substrates. Analysis of dynamic DMI is complicated by 2H label losses and kinetic isotope effects. Here, we modified a 13C‐based metabolic model to account for these effects in rat brain and validated DMI flux rates ...
Claudius S. Mathy +4 more
wiley +1 more source

