Results 21 to 30 of about 52,049 (355)
Impaired phosphocreatine metabolism in white adipocytes promotes inflammation
The mechanisms promoting disturbed white adipocyte function in obesity remain largely unclear. Herein, we integrate white adipose tissue (WAT) metabolomic and transcriptomic data from clinical cohorts and find that the WAT phosphocreatine/creatine ratio ...
S. Maqdasy +18 more
semanticscholar +1 more source
Background Numerous studies have demonstrated the efficacy of creatine supplementation for improvements in exercise performance. Few studies, however, have examined the effects of phosphocreatine supplementation on exercise performance.
John Paul V. Anders +10 more
doaj +1 more source
Cardiovascular diseases and energy deficiency: pathogenetic ways of correction
Cardiovascular disease remains one of the most common and influential causes of death worldwide, as the heart plays a key role in the human body. Energetic cardioprotective therapy of the myocardium is an important protective factor, regulating the ...
M.S. Cherska, H.M. Kukharchuk
doaj +1 more source
The current study aimed to evidence the strengths and weaknesses of two indirect methods for assessing the anaerobic alactic contribution to a specific CrossFit® workout.
Manoel Rios +4 more
doaj +1 more source
Nosological features of myocardial injury: an overview of the symposium
The main theme of the symposium «Nosological features of myocardial injury: how to recognize and what to do?» became cardioprotective therapy and the use of safe and highly effective metabolically active drugs for energy support of the myocardium.
E. O. Girutskaya
doaj +1 more source
Effect of allopurinol on phosphocreatine recovery and muscle function in older people with impaired physical function:a randomised controlled trial [PDF]
Background: Allopurinol has vascular antioxidant effects and participates in purinergic signalling within muscle. We tested whether allopurinol could improve skeletal muscle energetics and physical function in older people with impaired physical ...
Cavin, Ian +10 more
core +2 more sources
Use of exogenic phosphocreatine in ICU rehabilitation of patients with COVID-19 (pilot study)
The objective: to establish the possible effectiveness of exogenous phosphocreatine as a component of pharmacological support during the resuscitation stage of rehabilitation measures in critically ill patients with COVID-19.Subjects and Methods.
D. А. Krapivina +3 more
doaj +1 more source
Ischemic heart disease is the main cause of death globally. Cardioprotection is the process whereby mechanisms that reduce myocardial damage, and activate protective factors, contribute to the preservation of the heart. Targeting these processes could be
Ozlem Ozen Karakus +7 more
doaj +1 more source
Differentiating Creatine and Phosphocreatine In Vivo Using
ABSTRACT Purpose Validation and improvements to the proton MR spectroscopic measurement of creatine and phosphocreatine in vivo at 3 T. Methods Spectral simulations were used to evaluate and explore the mitigation of LCModel fitting bias due to lineshape, signal‐to‐noise (SNR) and non‐metabolite backgrounds with a focus on phosphocreatine and the ...
Ralph E. Hurd +9 more
openalex +2 more sources
There is an important unmet need to develop interventions that improve outcomes of hypoxic-ischaemic encephalopathy (HIE). Creatine has emerged as a promising neuroprotective agent.
Nhi Thao Tran +5 more
doaj +1 more source

