Results 21 to 30 of about 52,049 (355)

Impaired phosphocreatine metabolism in white adipocytes promotes inflammation

open access: yesNature Metabolism, 2022
The mechanisms promoting disturbed white adipocyte function in obesity remain largely unclear. Herein, we integrate white adipose tissue (WAT) metabolomic and transcriptomic data from clinical cohorts and find that the WAT phosphocreatine/creatine ratio ...
S. Maqdasy   +18 more
semanticscholar   +1 more source

The effects of phosphocreatine disodium salts plus blueberry extract supplementation on muscular strength, power, and endurance

open access: yesJournal of the International Society of Sports Nutrition, 2021
Background Numerous studies have demonstrated the efficacy of creatine supplementation for improvements in exercise performance. Few studies, however, have examined the effects of phosphocreatine supplementation on exercise performance.
John Paul V. Anders   +10 more
doaj   +1 more source

Cardiovascular diseases and energy deficiency: pathogenetic ways of correction

open access: yesМедицина неотложных состояний, 2023
Cardiovascular disease remains one of the most common and influential causes of death worldwide, as the heart plays a key role in the human body. Energetic cardioprotective therapy of the myocardium is an important protective factor, regulating the ...
M.S. Cherska, H.M. Kukharchuk
doaj   +1 more source

Pros and Cons of Two Methods of Anaerobic Alactic Energy Assessment in a High-Intensity CrossFit® Workout

open access: yesOxygen, 2022
The current study aimed to evidence the strengths and weaknesses of two indirect methods for assessing the anaerobic alactic contribution to a specific CrossFit® workout.
Manoel Rios   +4 more
doaj   +1 more source

Nosological features of myocardial injury: an overview of the symposium

open access: yesЛечащий Врач, 2021
The main theme of the symposium «Nosological features of myocardial injury: how to recognize and what to do?» became cardioprotective therapy and the use of safe and highly effective metabolically active drugs for energy support of the myocardium.
E. O. Girutskaya
doaj   +1 more source

Effect of allopurinol on phosphocreatine recovery and muscle function in older people with impaired physical function:a randomised controlled trial [PDF]

open access: yes, 2020
Background: Allopurinol has vascular antioxidant effects and participates in purinergic signalling within muscle. We tested whether allopurinol could improve skeletal muscle energetics and physical function in older people with impaired physical ...
Cavin, Ian   +10 more
core   +2 more sources

Use of exogenic phosphocreatine in ICU rehabilitation of patients with COVID-19 (pilot study)

open access: yesВестник анестезиологии и реаниматологии, 2022
The objective: to establish the possible effectiveness of exogenous phosphocreatine as a component of pharmacological support during the resuscitation stage of rehabilitation measures in critically ill patients with COVID-19.Subjects and Methods.
D. А. Krapivina   +3 more
doaj   +1 more source

Development of Triiodothyronine Polymeric Nanoparticles for Targeted Delivery in the Cardioprotection against Ischemic Insult

open access: yesBiomedicines, 2021
Ischemic heart disease is the main cause of death globally. Cardioprotection is the process whereby mechanisms that reduce myocardial damage, and activate protective factors, contribute to the preservation of the heart. Targeting these processes could be
Ozlem Ozen Karakus   +7 more
doaj   +1 more source

Differentiating Creatine and Phosphocreatine In Vivo Using 3 T 1 H MR Spectroscopy [PDF]

open access: hybridMagnetic Resonance in Medicine, Volume 95, Issue 4, Page 1896-1906, April 2026.
ABSTRACT Purpose Validation and improvements to the proton MR spectroscopic measurement of creatine and phosphocreatine in vivo at 3 T. Methods Spectral simulations were used to evaluate and explore the mitigation of LCModel fitting bias due to lineshape, signal‐to‐noise (SNR) and non‐metabolite backgrounds with a focus on phosphocreatine and the ...
Ralph E. Hurd   +9 more
openalex   +2 more sources

Assessing Creatine Supplementation for Neuroprotection against Perinatal Hypoxic-Ischaemic Encephalopathy: A Systematic Review of Perinatal and Adult Pre-Clinical Studies

open access: yesCells, 2021
There is an important unmet need to develop interventions that improve outcomes of hypoxic-ischaemic encephalopathy (HIE). Creatine has emerged as a promising neuroprotective agent.
Nhi Thao Tran   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy