Localized Semi-LASER Dynamic 31P Magnetic Resonance Spectroscopy of the Soleus During and Following Exercise at 7 T [PDF]
Object This study demonstrates the applicability of semi-LASER localized dynamic $^{31}$P MRS to deeper lying areas of the exercising human soleus muscle (SOL). The effect of accurate localization and high temporal resolution on data specificity is investigated.
arxiv +1 more source
Nitric oxide regulates skeletal muscle fatigue, fiber type, microtubule organization, and mitochondrial ATP synthesis efficiency through cGMP-dependent mechanisms [PDF]
Aim: Skeletal muscle nitric oxide–cyclic guanosine monophosphate (NO-cGMP) pathways are impaired in Duchenne and Becker muscular dystrophy partly because of reduced nNOSμ and soluble guanylate cyclase (GC) activity.
Balke, Jordan E+8 more
core +1 more source
Detection of Metabolites by Proton Ex Vivo NMR, in Vivo MR Spectroscopy Peaks and Tissue Content Analysis: Biochemical-Magnetic Resonance Correlation: Preliminary Results [PDF]
*Aim*: Metabolite concentrations by in vivo magnetic resonance spectroscopy and ex vivo NMR spectroscopy were compared with excised normal human tissue relaxation times and tissue homogenate contents. *Hypothesis*: Biochemical analysis
Arun Agrawala+2 more
core +1 more source
Analysis of repeated high-intensity running performance in professional soccer [PDF]
The aims of this study conducted in a professional soccer team were two-fold: to characterise repeated high-intensity movement activity profiles in official match-play; b) to inform and verify the construct validity of tests commonly used to determine ...
Batterham A. M.+10 more
core +1 more source
Cognitive-behavioral therapy for obsessive-compulsive disorder: access to treatment, prediction of long-term outcome with neuroimaging. [PDF]
This article reviews issues related to a major challenge to the field for obsessive-compulsive disorder (OCD): improving access to cognitive-behavioral therapy (CBT).
Feusner, Jamie D, O'Neill, Joseph
core +2 more sources
Interferon-γ acutely augments inhibition of neocortical layer 5 pyramidal neurons [PDF]
BACKGROUND: Interferon-γ (IFN-γ, a type II IFN) is present in the central nervous system (CNS) under various conditions. Evidence is emerging that, in addition to its immunological role, IFN-γ modulates neuronal morphology, function, and development in ...
Bräuer, Anja U.+7 more
core +1 more source
Influence of ischemia on the discharge rate in motor units during a sustained submaximal contraction [PDF]
Motor unit discharge patterns were observed under ischemic and non-ischemic conditions in the tibialis anterior during two sessions approximately 48 hours apart.
Gregg, Robert Henry
core +1 more source
Neuroprotective Effect of Phosphocreatine on Focal Cerebral Ischemia-Reperfusion Injury
Phosphocreatine (PCr) is a natural compound, which can donate high-energy phosphate group to ADP to synthesize ATP, even in the absence of oxygen and glucose. At present, it is widely used in cardiac and renal ischemia-reperfusion (IR) disease.
Tiegang Li, Nana Wang, Min Zhao
semanticscholar +1 more source
Transcription start site scanning and the requirement for ATP during transcription initiation by RNA polymerase II [PDF]
Saccharomyces cerevisiae RNA polymerase (Pol) II locates transcription start sites (TSS) at TATA-containing promoters by scanning sequences downstream from the site of preinitiation complex formation, a process that involves the translocation of ...
Fishburn, James+2 more
core +2 more sources
Effects of reduced-volume of sprint interval training and the time course of physiological and performance adaptations [PDF]
This study sought to determine the time course of training adaptations to two different sprint interval training programmes with the same sprint: rest ratio (1:8) but different sprint duration.
Babraj, J., Yamagishi, Takaki
core +1 more source