Results 51 to 60 of about 48,855 (331)

CARDIOPROTECTIVE EFFECTS OF PHOSPHOCREATINE

Вестник анестезиологии и реаниматологии, 2018
Goal of the review: to review theoretical and practical aspects of using exogenous phosphocreatine in the patients with cardio-vascular disorders in various clinical situations, given that phospho-transporting system disorders are the one of pathogenic ...
V. V. Lomivorotov, M. N. Abubakirov, E. V. Fominskiy, V. A. Shmyrev   +3 more
doaj   +1 more source

Creatine for the Treatment of Depression

Biomolecules, 2019
Depressed mood, which can occur in the context of major depressive disorder, bipolar disorder, and other conditions, represents a serious threat to public health and wellness.
Brent M. Kious, Douglas G. Kondo, Perry F. Renshaw   +2 more
doaj   +1 more source

Impaired aerobic capacity and premature fatigue preceding muscle weakness in the skeletal muscle Tfam-knockout mouse model

Disease Models & Mechanisms, 2021
Mitochondrial diseases are genetic disorders that lead to impaired mitochondrial function, resulting in exercise intolerance and muscle weakness. In patients, muscle fatigue due to defects in mitochondrial oxidative capacities commonly precedes muscle ...
Benjamin Chatel, Sylvie Ducreux, Zeina Harhous, Nadia Bendridi, Isabelle Varlet, Augustin C. Ogier, Monique Bernard, Julien Gondin, Jennifer Rieusset, Håkan Westerblad, David Bendahan, Charlotte Gineste   +11 more
doaj   +1 more source

The potential therapeutic effects of creatine supplementation on body composition and muscle function in cancer [PDF]

, 2018
Low muscle mass in individuals with cancer has a profound impact on quality of life and independence and is associated with greater treatment toxicity and poorer prognosis.
Fairman, C M, Galvao, D A, Hart, Nicolas H, Kendall, K L, Newton, R U, Taaffe, D R   +5 more
core   +2 more sources

Creatine supplementation and muscles: From metabolism to medical practice [PDF]

Romanian Journal of Medical Practice, 2021
Creatine has become the most popular dietary supplement in sport and exercise physiology. In humans creatine is synthesized by the kidneys, pancreas and liver and transported mainly into brain, skeletal and cardiac muscle.
Romana Vulturar, Bianca Jurjiu, Marc Damian, Anca Bojan, Sebastian Romeo Pintilie, Claudia Jurca, Adina Chis, Simona Grad   +7 more
doaj   +1 more source

Both Creatine and Its Product Phosphocreatine Reduce Oxidative Stress and Afford Neuroprotection in an In Vitro Parkinson’s Model

ASN Neuro, 2014
Creatine is the substrate for creatine kinase in the synthesis of phosphocreatine (PCr). This energetic system is endowed of antioxidant and neuroprotective properties and plays a pivotal role in brain energy homeostasis. The purpose of this study was to
M. Cunha, M. D. Martín-de-Saavedra, A. Romero, J. Egea, F. K. Ludka, C. Tasca, M. Farina, A. Rodrigues, Manuela G. López   +8 more
semanticscholar   +1 more source

In Vivo Quantification of Creatine Kinase Kinetics in Mouse Brain Using ³¹P-MRS at 7 T. [PDF]

NMR Biomed
We demonstrate the feasibility of using 31P‐MRS to quantify creatine kinase activity in the mouse brain on preclinical 7‐T scanners. A 20% drop in respiration increased the apparent forward rate constant by 36%, likely due to altered pH and mitochondrial ATP production.
Tachrount M, Smart S, Lerch J, Cherix A.
europepmc   +2 more sources

Phosphocreatine

Poultry Science, 1969
Abstract A few years ago Vorobev (1960) claimed that egg yolk and egg white of “White Leghorn” breed hen contains 1.5 mg. and 0.26 mg. of phosphocreatine-phosphorus, respectively. Recently, a column chromatography method has been developed (Wong, 1969) for the isolation and subsequent analysis of this compound.
openaire   +5 more sources

Localized Semi-LASER Dynamic 31P Magnetic Resonance Spectroscopy of the Soleus During and Following Exercise at 7 T [PDF]

, 2015
Object This study demonstrates the applicability of semi-LASER localized dynamic $^{31}$P MRS to deeper lying areas of the exercising human soleus muscle (SOL). The effect of accurate localization and high temporal resolution on data specificity is investigated.
arxiv   +1 more source

The impact of 60 days of ‐6° head down tilt bed rest on mitochondrial content, respiration and regulators of mitochondrial dynamics

The Journal of Physiology, EarlyView., 2023
Abstract figure legend Reductions in skeletal muscle mitochondrial respiration following 60 days of bed rest explained by a decrease in mitochondrial content, but resulting in an increase in OPA1 and Drp1 mediated mitochondrial fission. Abstract It is unclear how skeletal muscle metabolism and mitochondrial function adapt to long duration bed rest and ...
John Noone, Anthony Damiot, Helena Kenny, Isabelle Chery, Alexandre Zahariev, Sylvie Normand, François Crampes, Isabelle de Glisezinski, Keith D. Rochfort, Claire Laurens, Marie‐Pierre Bareille, Chantal Simon, Audrey Bergouignan, Stéphane Blanc, Donal J. O'Gorman   +14 more
wiley   +1 more source