Results 51 to 60 of about 52,049 (355)

Effect of selective heart rate slowing in heart failure with preserved ejection fraction [PDF]

, 2015
Background Heart failure with preserved ejection fraction (HFpEF) is associated with significant morbidity and mortality but is currently refractory to therapy.
Ashrafian, Houman, Dawson, Dana K., Dwight, Jeremy S., Francis, Jane M., Frenneaux, Michael, Mahmod, Masliza, Neubauer, Stefan, Pal, Nikhil, Rudd, Amelia, Singh, Satnam, Sivaswamy, Nadiya, Watkins, Hugh, Yavari, Arash   +12 more
core   +2 more sources

Neuroprotective effects of some creatine derivative compounds

Journal of Biological Research, 2010
Some derivatives more lipophylic than creatine, thus theoretically being capable to better cross the blood-brain barrier, were studied for their neuroprotective effect in mouse hippocampal slices.
L. Perasso, M. Giampieri, M. Mazzei, A. Parodi   +3 more
doaj   +1 more source

Efficacy of a four-week uphill sprint training intervention in field hockey players [PDF]

, 2016
Current evidence increasingly suggests that very short, supra-maximal bouts of exercise can have significant health and performance benefits. The majority of research conducted in the area however, uses laboratory-based protocols, which can lack ...
Babraj, John A., Jakeman, John R., McMullan, Judith   +2 more
core   +3 more sources

Impaired aerobic capacity and premature fatigue preceding muscle weakness in the skeletal muscle Tfam-knockout mouse model

Disease Models & Mechanisms, 2021
Mitochondrial diseases are genetic disorders that lead to impaired mitochondrial function, resulting in exercise intolerance and muscle weakness. In patients, muscle fatigue due to defects in mitochondrial oxidative capacities commonly precedes muscle ...
Benjamin Chatel, Sylvie Ducreux, Zeina Harhous, Nadia Bendridi, Isabelle Varlet, Augustin C. Ogier, Monique Bernard, Julien Gondin, Jennifer Rieusset, Håkan Westerblad, David Bendahan, Charlotte Gineste   +11 more
doaj   +1 more source

Developmental sensory experience balances cortical excitation and inhibition. [PDF]

, 2010
Early in life, neural circuits are highly susceptible to outside influences. The organization of the primary auditory cortex (A1) in particular is governed by acoustic experience during the critical period, an epoch near the beginning of postnatal ...
Barker, Alison J, Dorrn, Anja L, Froemke, Robert C, Schreiner, Christoph E, Yuan, Kexin   +4 more
core   +3 more sources

17β-Estradiol Effects in Skeletal Muscle: A ³¹P MR Spectroscopic Imaging (MRSI) Study of Young Females during Early Follicular (EF) and Peri-Ovulation (PO) Phases

Diagnostics
The natural variation in estrogen secretion throughout the female menstrual cycle impacts various organs, including estrogen receptor (ER)-expressed skeletal muscle.
Jimin Ren, Luis Rodriguez, Talon Johnson, Anke Henning, Yasin Y. Dhaher   +4 more
doaj   +1 more source

Elevated Tumor Lactate and Efflux in High-grade Prostate Cancer demonstrated by Hyperpolarized 13C Magnetic Resonance Spectroscopy of Prostate Tissue Slice Cultures. [PDF]

, 2020
Non-invasive assessment of the biological aggressiveness of prostate cancer (PCa) is needed for men with localized disease. Hyperpolarized (HP) 13C magnetic resonance (MR) spectroscopy is a powerful approach to image metabolism, specifically the ...
Ahamed, Fayyaz, Bok, Robert A, DeLos Santos, Justin, Keshari, Kayvan R, Kurhanewicz, John, Nolley, Rosalie, Peehl, Donna M, Qin, Hecong, Santos, Romelyn DeLos, Sriram, Renuka, Tabatabai, Z Laura, Van Criekinge, Mark, Vigneron, Daniel B   +12 more
core   +1 more source

Both Creatine and Its Product Phosphocreatine Reduce Oxidative Stress and Afford Neuroprotection in an In Vitro Parkinson’s Model

ASN Neuro, 2014
Creatine is the substrate for creatine kinase in the synthesis of phosphocreatine (PCr). This energetic system is endowed of antioxidant and neuroprotective properties and plays a pivotal role in brain energy homeostasis. The purpose of this study was to
M. Cunha, M. D. Martín-de-Saavedra, A. Romero, J. Egea, F. K. Ludka, C. Tasca, M. Farina, A. Rodrigues, Manuela G. López   +8 more
semanticscholar   +1 more source

The effect of previous wingate performance using one body region on subsequent wingate performance using a different body region [PDF]

, 2017
The 30 second Wingate Anaerobic Test (WAnT) is the gold standard measure of anaerobic performance. The present investigation aimed to determine if a previous WAnT using one body region significantly affected a subsequent WAnT using a different body ...
Bousson, Matthew, Harvey, Leonie, Lovell, Dale, McLellan, Chris   +3 more
core   +1 more source

Creatine for the Treatment of Depression

Biomolecules, 2019
Depressed mood, which can occur in the context of major depressive disorder, bipolar disorder, and other conditions, represents a serious threat to public health and wellness.
Brent M. Kious, Douglas G. Kondo, Perry F. Renshaw   +2 more
doaj   +1 more source