Results 61 to 70 of about 31,996 (262)

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Amplified detection of phosphocreatine and creatine after supplementation using CEST MRI at high and ultrahigh magnetic fields

, 2020
Creatine is an important metabolite involved in muscle contraction. Administration of exogenous creatine (Cr) or phosphocreatine (PCr) has been used for improving exercise performance and protecting the heart during surgery including during valve ...
Jens T. Rosenberg, Shannon Helsper, Michael T. McMahon, Helsper, Shannon, Rosenberg, Jens T., Shaowei Bo, Bo, Shaowei, Pavuluri, KowsalyaDevi, KowsalyaDevi Pavuluri, McMahon, Michael T.   +9 more
core   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Bioenergetic Profiling in Exercise: Methods, Limitations and Practical Applications—A Narrative Review

Physiologia
Quantifying oxidative, glycolytic, and phosphagen energy system contributions during exercise is challenging due to their simultaneous activation and reliance on indirect estimation.
Manoel J. Rios, David B. Pyne, Ricardo J. Fernandes   +2 more
doaj   +1 more source

Data on triiodothyronine treated peroxisome proliferator-activated receptor-alpha-null mouse hearts using magnetic resonance imaging and magnetic resonance spectroscopy

Data in Brief, 2018
This data contain left ventricular end-diastolic volumes, end-systolic volumes, stroke volumes, ejection fractions, cardiac outputs, heart rates, phosphocreatine concentrations, adenosine 5’-triphosphate (ATP) concentrations, total creatine ...
Wen Zhang, Michiel ten Hove, Jürgen E. Schneider, Kieran Clarke   +3 more
doaj   +1 more source

phosphocreatine muscle resynthesis rate in healthy adults

, 2021
Dynamic phosphorus MRS ( P-MRS) is a method used for in vivo studies of skeletal muscle energetics including measurements of phosphocreatine (PCr) resynthesis rate during recovery of submaximal exercise.
Eric Ravussin, Singh, Maninder, Hanet, Sebastian, Covington, Jeffrey, Owen T. Carmichael, Sebastian Hanet, Maninder Singh, Darpolor, Moses M, Jeffrey Covington, Ravussin, Eric, Carmichael, Owen T, Moses M. Darpolor   +11 more
core   +1 more source

Blood Biomarkers of Helicobacter pylori‐Infected Chronic Gastritis in Active Versus Stable Phases: A Clinical Indicator Analysis Combined With Proteomic and Metabolomic Investigations

iMetaMed, EarlyView.
Combining clinical data with serum proteomics and metabolomics, the HGB–CAPZB–acetic acid model was developed as a potential diagnostic index to distinguish the active and stable stages of Helicobacter pylori‐infected chronic gastritis, and the related mechanism was explored through multi‐omics.
Tiantong Jiang, Zhen Ma, Yang Li, Shaoli Wang, Yanjiao Zhang, Lei Song, Xianyu Li, Zhen Liu   +7 more
wiley   +1 more source

Metabolic Response of the Immature Right Ventricle to Acute Pressure Overloading

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundSurgical palliation or repair of complex congenital heart disease in early infancy can produce right ventricular (RV) pressure overload, often leading to acute hemodynamic decompensation.
Masaki Kajimoto, Muhammad Nuri, Nancy G. Isern, Isabelle Robillard‐Frayne, Christine Des Rosiers, Michael A. Portman   +5 more
doaj   +1 more source

Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue

iNew Medicine, EarlyView.
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao, Jingjing Sun, Yan Lu, Ying Yang   +3 more
wiley   +1 more source

Abstract 096 | Hidden energy deficiency and therapeutic strategies for its correction

European Journal of Translational Myology
Energy consumption and production in the human body underpin the metabolic processes essential for life. Adenosine triphosphate (ATP) is the universal energy currency for all biochemical metabolic reactions; its synthesis and turnover require a supply ...
Natalia F. Tumanova-Ponomareva
doaj   +1 more source