Results 61 to 70 of about 26,828 (231)

No effect of creatine supplementation on oxidative stress and cardiovascular parameters in spontaneously hypertensive rats

Journal of the International Society of Sports Nutrition, 2012
Background Exacerbated oxidative stress is thought to be a mediator of arterial hypertension. It has been postulated that creatine (Cr) could act as an antioxidant agent preventing increased oxidative stress.
Alves Christiano RR, Murai Igor H, Ramona Pamella, Nicastro Humberto, Bechara Luiz RG, Lancha Antonio H, Brum Patrícia C, Irigoyen Maria C, Gualano Bruno   +8 more
doaj   +1 more source

Phosphocreatine in Insulinized Frogs.

Experimental Biology and Medicine, 1929
Fiske and Subbarow1 have isolated phosphocreatine from protein-free muscle filtrates and find “that the compound is destroyed during contraction at a rate which rivals that of glycogenolysis and lactic acid production.” Modern theories of muscle contraction have as their foundation the change of glycogen into lactic acid. But it has been shown that the
J. M. D. Olmsted, H. Mackler
openaire   +1 more source

Targeting eIF5A combats breast cancer progression by ClpP‐dependent mitochondrial oxidative stress

Interdisciplinary Medicine, EarlyView.
This study identified the eIF5A‐ClpP axis as a key driver of breast cancer progression. Targeting eIF5A suppresses tumor growth by inducing ClpP‐dependent mitochondrial oxidative stress, revealing a novel therapeutic vulnerability. Abstract Breast cancer (BC) poses a persistent global health challenge, necessitating new therapeutic targets.
Jinmei Zhu, Baoyuan Tang, Bei Xie, Haohua Deng, Haitang Yang, Lei Ma, Ziqing Zhang, Yicheng Ma, Xingyuan Ma, Shuaiyang Wang, Jing Li, Lei Zhao, Wengui Shi, Linjing Li   +13 more
wiley   +1 more source

Comparison Between Respiratory‐Triggered and Free‐Breathing Signal Acquisition Methods for Single‐Voxel Phosphorus Magnetic Resonance Spectroscopy of the Liver on a Clinical System

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background The optimal protocol for clinical liver 31P‐magnetic resonance spectroscopy (MRS) remains unclear. Single‐voxel 31P‐MRS using image‐selected in vivo spectroscopy (ISIS) employs respiratory‐triggering (RT) or free‐breathing (FB) acquisition.
Kumi Ozaki, Jihun Kwon, Marc Van Cauteren, Yasutomo Katsumata, Yukichi Tanahashi, Satoshi Goshima   +5 more
wiley   +1 more source

Data on triiodothyronine treated peroxisome proliferator-activated receptor-alpha-null mouse hearts using magnetic resonance imaging and magnetic resonance spectroscopy

Data in Brief, 2018
This data contain left ventricular end-diastolic volumes, end-systolic volumes, stroke volumes, ejection fractions, cardiac outputs, heart rates, phosphocreatine concentrations, adenosine 5’-triphosphate (ATP) concentrations, total creatine ...
Wen Zhang, Michiel ten Hove, Jürgen E. Schneider, Kieran Clarke   +3 more
doaj   +1 more source

Metabolic and Volumetric Alterations in the Basal Ganglia and the Cerebellum in Dopa‐Responsive Dystonia in Symptomatic and Asymptomatic GCH1 Mutation Carriers

Movement Disorders, EarlyView.
ABSTRACT Background Dopa‐responsive dystonia is caused by pathogenic variants in the GCH1 gene. Although its clinical features and reduced penetrance are known, in vivo metabolic and structural alterations in symptomatic (sMC) and asymptomatic mutation carriers (aMC) remain poorly understood.
Jannik Prasuhn, Leon van Well, Marta M. Pokotylo, Feline Hamami, Joke‐Lina Aßmann, Katja Lohmann, Maximilian G. Ködderitzsch‐Mertins, Julia Henkel, Jan Uter, Alexander Münchau, Christine Klein, Anne Weissbach, Norbert Brüggemann   +12 more
wiley   +1 more source

Metabolic Response of the Immature Right Ventricle to Acute Pressure Overloading

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundSurgical palliation or repair of complex congenital heart disease in early infancy can produce right ventricular (RV) pressure overload, often leading to acute hemodynamic decompensation.
Masaki Kajimoto, Muhammad Nuri, Nancy G. Isern, Isabelle Robillard‐Frayne, Christine Des Rosiers, Michael A. Portman   +5 more
doaj   +1 more source

GABA+‐Edited Magnetic Resonance Spectroscopy Deep Learning Quality Assessment Framework

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Motivated by the need to improve GABA+‐edited magnetic resonance spectroscopy (MRS) quality, we developed a three‐module framework to improve transient averaging based on quality. We hypothesized that training a deep learning (DL) model to differentiate spectrum quality could improve transient averaging compared to traditional ...
Hanna Bugler, Roberto Souza, Ashley D. Harris   +2 more
wiley   +1 more source

Bioenergetic Profiling in Exercise: Methods, Limitations and Practical Applications—A Narrative Review

Physiologia
Quantifying oxidative, glycolytic, and phosphagen energy system contributions during exercise is challenging due to their simultaneous activation and reliance on indirect estimation.
Manoel J. Rios, David B. Pyne, Ricardo J. Fernandes   +2 more
doaj   +1 more source

Phosphocreatine in Red and White Muscle

Experimental Biology and Medicine, 1951
ConclusionThe creatine phosphate content of the white breast muscle of the fowl was found to be over twice as great as that of the red leg muscle. In the “flying” bird, the pigeon, the red breast muscle and the leg muscle contained approximately the same levels of this high energy phosphate.
openaire   +2 more sources