Results 61 to 70 of about 48,855 (331)

Phosphocreatine in Insulinized Frogs.

Experimental Biology and Medicine, 1929
Fiske and Subbarow1 have isolated phosphocreatine from protein-free muscle filtrates and find “that the compound is destroyed during contraction at a rate which rivals that of glycogenolysis and lactic acid production.” Modern theories of muscle contraction have as their foundation the change of glycogen into lactic acid. But it has been shown that the
H. Mackler, J. M. D. Olmsted
openaire   +2 more sources

17β-Estradiol Effects in Skeletal Muscle: A ³¹P MR Spectroscopic Imaging (MRSI) Study of Young Females during Early Follicular (EF) and Peri-Ovulation (PO) Phases

Diagnostics
The natural variation in estrogen secretion throughout the female menstrual cycle impacts various organs, including estrogen receptor (ER)-expressed skeletal muscle.
Jimin Ren, Luis Rodriguez, Talon Johnson, Anke Henning, Yasin Y. Dhaher   +4 more
doaj   +1 more source

The Protective Effect of Cx43 Protein-Mediated Phosphocreatine on Myocardial Ischemia/Reperfusion Injury

Cardiology Research and Practice, 2021
Objectives. To verify the protective effect of phosphocreatine on myocardium in an ischemic model and the possible mechanism of action. Methods. The model of myocardial ischemia/reperfusion (I/R) was established by the ligation balloon method. 30 SD rats
Chen-xi Wang, Jun-jun Guo, An-jie Di, Yu Zhu, Wei-min Han, An-ran Cheng, Cheng Li, Rui-chan Si, Tian-shu Lan, Ran Zhang, Hong-li Liu, Guo-liang Yan   +11 more
doaj   +1 more source

Analysis of repeated high-intensity running performance in professional soccer [PDF]

, 2012
The aims of this study conducted in a professional soccer team were two-fold: to characterise repeated high-intensity movement activity profiles in official match-play; b) to inform and verify the construct validity of tests commonly used to determine ...
Batterham A. M., Carling C., Christopher Carling, Franck Le Gall, Gregory Dupont, Iaia F. M., Nédélec M., O'Donoghue P. G., O'Donoghue P. G., Oliver J. L., Reilly T.   +10 more
core   +1 more source

HUMAN IMMUNE SYSTEM AND PHYSICAL EXERCISE

Медицинская иммунология, 2014
. Physiological and biochemical changes proceeding in muscles during physical loads exert systemic influence upon protein biosynthesis. This process is accelerated in presence of free amino acids, sufficient quantities of hormones, creatine, hydrogen ...
Z. Ch. Musin, S. V. Latukhov
doaj   +1 more source

Exploration of human brain tumour metabolism using pairwise metabolite-metabolite correlation analysis (MMCA) of HR-MAS 1H NMR spectra. [PDF]

PLoS ONE, 2017
We quantified 378 HRMAS 1H NMR spectra of human brain tumours (132 glioblastomas, 101 astrocytomas, 75 meningiomas, 37 oligodendrogliomas and 33 metastases) from the eTumour database and looked for metabolic interactions by metabolite-metabolite ...
Basetti Madhu, Alexandra Jauhiainen, Sean McGuire, John R Griffiths   +3 more
doaj   +1 more source

A clinical case of cardioprotective therapy with exogenous phosphocreatine during chemotherapy and anti HER2-neu therapy in a patient with breast cancer

Клинический разбор в общей медицине, 2023
The authors describe a clinical observation of cardiotoxicity of anticancer targeted therapy in a young patient with HER2neu-positive breast cancer. The results of instrumental examinations demonstrating manifestations of cardiotoxicity are presented ...
Andrey L. Pylev, Vyacheslav A. Lisovoy, Olga S. Kozlova   +2 more
doaj   +1 more source

Nitric oxide regulates skeletal muscle fatigue, fiber type, microtubule organization, and mitochondrial ATP synthesis efficiency through cGMP-dependent mechanisms [PDF]

, 2016
Aim: Skeletal muscle nitric oxide–cyclic guanosine monophosphate (NO-cGMP) pathways are impaired in Duchenne and Becker muscular dystrophy partly because of reduced nNOSμ and soluble guanylate cyclase (GC) activity.
Balke, Jordan E, Brouckaert, Peter, Buys, Emmanuel S, Knowels, Gary, Madorma, Derik, Marcinek, David J, Moon, Younghye, Percival, Justin M, Siegel, Michael P   +8 more
core   +1 more source

How Does Creatine Supplementation Affect Physical Performance and Muscle Recovery? - A Literature Review of Its Effects, Mechanisms of Action, Safety and Side Effects

Quality in Sport
Introduction: Creatine is a naturally occurring compound that plays a primary role in energy metabolism, particularly within muscle cells. Its main sites of synthesis include the liver, kidneys, and pancreas [1,2].
Martyna Pacanowska, Małgorzata Blecharczyk, Igor Zydlewski, Martyna Mrozek, Alicja Nowik, Marcin Sękulski, Maciej Kosiński, Paweł Jakubiec   +7 more
doaj   +1 more source

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer

Advanced Science, EarlyView.
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska, Paula Allepuz‐Fuster, Chloé Maurizy, Alexandre Hego, Sandra Ormenese, Quentin Lion, Arnaud Blomme, Pierre Close, Arnaud Lavergne, Latifa Karim, Marc Thiry, Ivan Nemazanyy, Roopesh Krishnankutty, Jair Marques Jr, Alex von Kriegsheim, Nathaniel F. Henneman, Ganna Panasyuk, Kateryna Shostak, Alain Chariot   +18 more
wiley   +1 more source