Results 81 to 90 of about 52,049 (355)
Mitochondrial DNA depletion by ethidium bromide decreases neuronal mitochondrial creatine kinase: Implications for striatal energy metabolism. [PDF]
PLoS ONE, 2017 Mitochondrial DNA (mtDNA), the discrete genome which encodes subunits of the mitochondrial respiratory chain, is present at highly variable copy numbers across cell types.
Emily Booth Warren +3 more
doaj +1 more source
Considerations for drug trials in hypertrophic cardiomyopathy
ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant +17 more
wiley +1 more source
Influence of recovery intensity on oxygen demand and repeated sprint performance [PDF]
, 2016 AIM: This study aimed to determine effects of recovery intensity (passive, 20, 30 and 40%V̇ O2peak) on oxygen uptake kinetics, performance and blood lactate accumulation during repeated sprints.
Babraj, J., Yamagishi, T.
core +1 more source
Creatine kinase in energy metabolic signaling in muscle [PDF]
, 2007 There has been much debate on the mechanism of regulation of mitochondrial ATP synthesis to balance ATP consumption during changing cardiac workloads. A key role of creatine kinase (CK) isoenzymes in this regulation of oxidative phosphorylation and in ...
Johannes H. G. M. van Beek, Olav Kongas
core +2 more sources
Neuroprotective Effect of Phosphocreatine on Focal Cerebral Ischemia-Reperfusion Injury
Journal of Biomedicine and Biotechnology, 2012 Phosphocreatine (PCr) is a natural compound, which can donate high-energy phosphate group to ADP to synthesize ATP, even in the absence of oxygen and glucose. At present, it is widely used in cardiac and renal ischemia-reperfusion (IR) disease.
Tiegang Li, Nana Wang, Min Zhao
semanticscholar +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1427-1436, April 2025.Abstract Background and objectives Initially described as a benign acute cardiomyopathy, Takotsubo syndrome has been linked to elevated mortality rates. Emerging evidence suggests that unresolved myocardial inflammation may contribute to this adverse prognosis.
Loïc Faucher +12 more
wiley +1 more source
The hydrolysis of phosphocreatine and the origin of urinary creatinine [PDF]
, 1947 Shaffer (1), Myers and Fine (2), and Hahn and Meyer (3) adduced evidence that muscle creatine is the precursor of urinary creatinine. This was questioned by Chanutin and Kinard (4) but was conclusively proved by Bloch, Schoenheimer, and Rittenberg (5, 6)
Borsook, Henry, Dubnoff, Jacob W.
core
Effects of oral creatine supplementation on high intensity, intermittent exercise performance in competitive squash players [PDF]
, 2001 The purpose of this study was to determine the effects of oral creatine supplementation on high intensity, intermittent exercise performance in competitive squash players. Nine squash players (mean ± SEM V˙O2max = 61.9 ± 2.1ml · kg-1 · min-1; body mass =
Barrington, JP +2 more
core +1 more source
Phosphocreatine Content of Mammalian Cardiac Muscle.
Experimental Biology and Medicine, 1953 Summary1. “Resting” values for the phosphocreatine content of the ventricles of several mammalian species are reported and an explanation is offered for some of the low values recorded in the literature. The necessary precautions are noted if maximal values are to be obtained. 2.
G, FAWAZ, E S, HAWA
openaire +2 more sources
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source