Results 181 to 190 of about 225,115 (385)
Inhibitors of phosphodiesterase as cancer therapeutics.
European journal of medicinal chemistry, 2018 Ting Peng +7 more
semanticscholar +1 more source
Aging Cell, EarlyView.Canagliflozin enhances hippocampal function, reduces Aβ pathology, and improves cognitive function in male mice, while females show limited benefits, revealing sex‐specific neuroprotective responses across aging and Alzheimer's models. ABSTRACT Aging is the strongest risk factor for cognitive decline and Alzheimer's disease (AD), yet the mechanisms ...
Hashan Jayarathne +11 more
wiley +1 more source
Action of Venom Phosphodiesterase on Deoxyribonucleic Acid
, 1961 Edward J. Williams +2 more
openalex +1 more source
A comparison of the activity of phosphatidylinositol phosphodiesterase against substrate in dispersions and as monolayers at the air-water interface [PDF]
, 1975 Peter J. Quinn, Y. Barenholz
openalex +1 more source
Phosphodiesterase‐5 Inhibition and Alzheimer's Disease Risk: A Mendelian Randomisation Study
Aging Cell, EarlyView.Preclinical studies suggest PDE5 inhibitors may improve cognition, but observational evidence on Alzheimer's disease (AD) risk is mixed. We performed a cis‐Mendelian randomisation analysis across four AD genome‐wide association studies (GWAS) datasets and a sex‐stratified analysis using UK Biobank data.
Marta Alcalde‐Herraiz +9 more
wiley +1 more source
Human placental cAMP phosphodiesterase activity kinetic properties and sensitivity to some drugs and hormones [PDF]
, 1975 F. Ferré, M. Breuiller, L. Cédard
openalex +1 more source
Bull semen phosphodiesterase [PDF]
Biochemical Journal, 1972 A Kher, S R Anand
openaire +3 more sources
Academic Emergency Medicine, EarlyView.ABSTRACT Background Morbidity and mortality in cardiogenic pulmonary edema have been reduced by noninvasive positive‐pressure airway maneuvers. The value of continuous positive airway pressure (CPAP) for the treatment of high‐altitude pulmonary edema (HAPE) is uncertain.
Todd Bolotin +8 more
wiley +1 more source