Results 221 to 230 of about 225,115 (385)

Engineering of a red-light–activated human cAMP/cGMP-specific phosphodiesterase

Proceedings of the National Academy of Sciences of the United States of America, 2014
C. Gasser, Sandra Taiber, Chen-Min Yeh, C. Wittig, P. Hegemann, S. Ryu, F. Wunder, Andreas Möglich   +7 more
semanticscholar   +1 more source

Pharmacokinetics, pharmacodynamics, and safety interaction study of tunodafil hydrochloride and alcohol: A randomized, blinded, placebo‐controlled, three‐cycle crossover study in Chinese healthy men

Andrology, EarlyView.
Abstract Objectives This study aimed to evaluate the pharmacodynamic effects of administering tunodafil hydrochloride with alcohol on blood pressure and heart rate in healthy Chinese males, and to investigate the mutual pharmacokinetic interactions and safety of the combination.
Dingyuan Hu, Suping Niu, Fan Huang, Lu Jin, Qun Gu, Yanting Li, Chongyou Lee, Zhenwei Xie, Xiangxing Liu, Fang Men, Wenyan Zhao, Shuang Li, Yian Liu, Qian Wang, Huaying Fan, Jiaojiao Zhang, Shuangshuang Lin, Liming Chen, Yi Fang   +18 more
wiley   +1 more source

The Role of Phosphodiesterase-5 Enzyme Inhibitors and Prostacyclin Analogs in Reactive Pulmonary Vasculopathy in Systolic Heart Failure: A Narrative Review. [PDF]

Cureus
Sekharamahanti HE, Patel DV, Prajapati M, Sirekulam V, Shah P, Peracha HT, Patel S, Makineni KS, Anene JI, Harish R, Mansfield AM.   +10 more
europepmc   +1 more source

CLINICAL SIGNIFICANCF OF SERUM PHOSPHODIESTERASE ACTIVITIES IN VIRAL HEPATITIS

, 1965
Shigeyoshi Inui, I. Aoyama, Fumihiko Watanabe, Hiroyuki Kawase, Miyoji OHASHI, Toshihide KANDA, Yotaro SUGIURA, Naoki Tokimitsu, Michinori ENYA, K Oida, Shigeto ANDO, Hiroshi Ando, Mineo Kojima, Kazuo Nagata, K. Hashiyama, Tadasi KANIE, Kanetoshi SETTA, Hitoshi IRIYAMA   +17 more
openalex   +2 more sources

Proteomic profiling of porcine seminal extracellular vesicles reveals potential in vivo fertility biomarkers

Andrology, EarlyView.
Abstract Background Predicting male fertility in farm animals remains a challenge. Seminal plasma (SP) contains a high amount of heterogeneous seminal extracellular vesicles (sEVs), believed involved in reproductive processes and maybe key to understanding male fertility.
Isabel Barranco, Pablo Martínez‐Díaz, Ana Parra, María José Martínez‐Alborcia, Xiomara Lucas, Heriberto Rodríguez‐Martínez, Jordi Roca   +6 more
wiley   +1 more source

Efficacy and Safety of Phosphodiesterase-5 Inhibitors for Erectile Dysfunction in Schizophrenia: A Systematic Review and Meta-Analysis. [PDF]

Neuropsychiatr Dis Treat
Saito A, Sakuma K, Iwata N, Kishi T.
europepmc   +1 more source

Stereochemistry of hydrolysis by snake venom phosphodiesterase.

, 1979
Peter Burgers, F. Eckstein, D. H. Hunneman   +2 more
openalex   +1 more source

Comparative efficacy of combination therapy including regenerative therapies versus monotherapy for erectile dysfunction: A systematic review and meta‐analysis

Andrology, EarlyView.
Abstract Background and objective The Current European Association of Urology guidelines do not provide recommendation for combination of regenerative therapies with standard therapies for erectile dysfunction. The aim of this study was to compare the efficacy of combined regenerative therapy with monotherapy for erectile dysfunction.
Alberto Quistini, Giuseppe Fallara, Marco Tozzi, Massimiliano Depalma, Rocco Damiano, Alessandro Palmieri, Fabio Castiglione, Andrea Salonia, Roberto Bianchi, Matteo Ferro, Asif Muneer, Hussain M. Alnajjar, Karl H. Pang   +12 more
wiley   +1 more source

The safety and efficacy of phosphodiesterase type 5 inhibitors in the treatment of diabetic erectile dysfunction: a systematic review and meta-analysis. [PDF]

PeerJ
Zhu Z, Xu J, Dai B, Lin M, Yang H, Liu S, Bao P, Nan Z.   +7 more
europepmc   +1 more source

Low testosterone levels in men at age 31 associates with future risk of prediabetes and type 2 diabetes: A birth cohort study

Andrology, EarlyView.
Abstract Objective We aimed to investigate the association of a low serum testosterone concentration with the risk of abnormal glucose metabolism (i.e., prediabetes and type 2 diabetes) in men at a 15‐year follow‐up. Study population and methods In a population birth cohort, men with low testosterone (testosterone < 12.1 nmol/L, n = 136) and normal ...
Tuomisto A, Pinola P, Pesonen P, Franks S, Martikainen H, Tapanainen JS, Niinimäki M, Morin‐Papunen L   +7 more
wiley   +1 more source