Results 91 to 100 of about 47,423 (289)

Periodontitis in patients with severe erectile dysfunction undergoing penile prosthesis implantation: Clinical and immunohistochemical study

Journal of Periodontology, EarlyView.
Abstract Background The relationship between periodontitis and erectile dysfunction (ED) has been poorly documented in Caucasian populations, particularly severe ED (SED) requiring penile prostheses. This study aimed to evaluate the association between periodontitis and SED in patients undergoing penile prosthesis implantation, and to identify clinical
Miguel Ángel Arrabal‐Polo, Ana López‐Toruño, Antonio Magan‐Fernández, Miguel Arrabal Martin, Natividad Martín‐Morales, Eva Rosel, Manuel Bravo, Francisco O´Valle, Francisco Mesa   +8 more
wiley   +1 more source

The Selective Phosphodiesterase-5 Inhibitor Tadalafil Induces Microvascular and Metabolic Effects in Type 2 Diabetic Postmenopausal Females [PDF]

, 2012
Giuseppe Murdolo, Mikaela Sjöstrand, Lena Strindberg, Peter Lönnroth, Per‐Anders Jansson   +4 more
openalex   +1 more source

Phenotypical Effect of Phosphodiesterase 5 (PDE5) Inhibitor on Behavioral Activities of Fruit Fly Drosophila melanogaster

, 2021
Azan Jaya, Elly Wahyudin, Yulia Yusrini Djabir, Tri Puspita Roska, Rudi Arfiansyah, Andi Dirpan, Firzan Nainu, A Bender, J Beavo, K Omori, J Kotera, W Ahmed, A Geethakumari, K Biswas, S Huang, J Lie, L Dong, X Zhang, X Yan, Y Shen, X Yu, Y Li, V Boswell-Smith, D Spina, C Page, N Gali, H Ghofrani, A Torbicki, R Barst, L Rubin, D Badesch, T Fleming, T Parpia, G Burgess, A Branzi, F Grimminger, M Kurzyna, G Simonneau, K Andersson, J Pich, C Madeira, F Tonin, M Fachi, H Borba, V Ferreira, L Leonart, A Bonetti, R Moritz, A Trindade, A Gonalves, F Fernandez-Llimos, R Pontarolo, C Peixoto, F Gomes, J Tanus-Santos, Y Fan, R Zhang, X Jiang, L Wen, D Wu, D Liu, P Yuan, Y Wang, Z Jing, E Zuccarello, E Acquarone, E Calcagno, E Argyrousi, S Deng, D Landry, O Arancio, J Fiorito, M Giorgi, S Cardarelli, F Ragusa, M Saliola, S Biagioni, G Poiana, F Naro, M Massimi, U Pandey, C Nichols, B Ugur, K Chen, H Bellen, F Nainu, Y Nakanishi, A Shiratsuchi, C Chow, L Reiter, F Nainu, E Salim, R Asri, A Hori, T Kuraishi, R Asri, E Salim, F Nainu, A Hori, T Kuraishi   +99 more
openalex   +1 more source

Patient Characteristics, Disease Profile and Treatment Patterns in Mild and Moderate Psoriasis Patients: Results From Real‐World Clinical Practices in Five European Countries (PROSPECT Study)

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Categorisation of psoriasis (PsO) disease severity in patients varies, although body surface area (BSA) affected is commonly used (< 3% ‘mild’, 3%–10% ‘moderate’ and > 10% ‘severe’). While moderate‐severe PsO has been well‐studied, more limited information regarding mild‐to‐moderate PsO is available.
Emily Goddard, Aaron Keal, James Hetherington, Sophie Barlow, David Wu, Melany Worbes‐Cerezo, Alexander Litvintchouk   +6 more
wiley   +1 more source

Beyond Erectile Dysfunction: cGMP-Specific Phosphodiesterase 5 Inhibitors for Other Clinical Disorders

, 2022
Arun Samidurai, Lei Xi, Anindita Das, Rakesh C. Kukreja   +3 more
openalex   +1 more source

Clinical Efficacy and Safety of Topical Roflumilast in Psoriasis: An Updated Systematic Review and Meta‐Analysis of Randomized Controlled Trials

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Traditional first‐line topical treatments for plaque psoriasis, particularly corticosteroids and vitamin D analogs, frequently have only limited efficacy for long‐term use, and present difficulties with safety and adherence. Objectives In this systematic review and meta‐analysis of randomized controlled trials (RCTs), we assessed ...
Aimal A. Khattak, Ahmed Javed, Ummi Aiman Rahman, Rumaisa Riaz, Zeeshan Imtiaz, Hassan A. Mirza, Farman U. Khan, Muhid Khattak, Fatima Javid, Abdul Moiz Khan, Adeline L. Roy, Bibek Shrestha   +11 more
wiley   +1 more source

Advances in the treatment of Raynaud&rsquo;s phenomenon

Vascular Health and Risk Management, 2010
Terri L LevienDrug Information Pharmacist and Clinical Associate Professor, College of Pharmacy, Washington State University Spokane, WA, USAAbstract: Raynaud&rsquo;s phenomenon is a common condition characterized by vasospasm of the digital arteries
Terri L Levien
doaj  

New Biologic and Small Molecule Therapies for Hidradenitis Suppurativa

JEADV Clinical Practice, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is an inflammatory skin disease that has historically been underdiagnosed and, until recently, under‐researched. Furthermore, the pathophysiology of HS is complex, and not fully understood. Just three biologic medications—adalimumab (anti‐TNF‐α), secukinumab (anti‐IL17A) and bimekizumab (anti‐IL17A/F) are licensed
Emily Pender, Rosalind Hughes, Brian Kirby   +2 more
wiley   +1 more source

Use of phosphodiesterase 5 inhibitors is not associated with ocular adverse events. [PDF]

J Sex Med, 2023
Belladelli F, Li S, Zhang CA, Muncey W, Del Giudice F, Glover F, Seranio N, Basran S, Fallara G, Montorsi F, Salonia A, Eisenberg ML.   +11 more
europepmc   +1 more source

Systematic Deciphering of ATBC Nephrotoxicity Mechanisms via Machine Learning and Single‐Cell Analysis

Medicine Bulletin, EarlyView.
This study elucidates the nephrotoxic mechanism of acetyl tributyl citrate (ATBC) by integrating network toxicology, machine learning, and single‑cell multi‑omics analysis to systematically decipher the molecular mechanisms and cell‑type‑specific regulatory networks underlying ATBC‑induced kidney injury. First, a protein‑protein interaction network was
Yimao Wu, Yalun Liang, Jintao Liang, Wenlong Sun, Qian Zhang, Meng‐Yao Li   +5 more
wiley   +1 more source