Results 251 to 260 of about 47,423 (289)

Low‐intensity shockwave therapy for erectile dysfunction due to diabetes mellitus or coronary artery disease: An individual participant data meta‐analysis from a single center

Andrology, Volume 14, Issue 2, Page 348-351, February 2026.
Abstract Background Low‐intensity shockwave therapy (LiST) is a first‐line treatment for vasculogenic erectile dysfunction (ED). However, its efficacy in challenging cases, such as ED solely due to type 2 diabetes mellitus (DM) or coronary artery disease (CAD), has not been adequately assessed.
Nikolaos Pyrgidis, Dimitrios Kalyvianakis, Ioannis Mykoniatis, Dimitrios Hatzichristou   +3 more
wiley   +1 more source

Analysis of Phosphodiesterase Type 5 Inhibitors and Analogues as Adulterants in Herbal Dietary Food Supplements in Saudi Market Using Green UPLC-MS/MS Method: Assessment of the Greenness and Whiteness Profiles

Ahmed Mostafa
openalex   +1 more source

Pharmacokinetics, pharmacodynamics, and safety interaction study of tunodafil hydrochloride and alcohol: A randomized, blinded, placebo‐controlled, three‐cycle crossover study in Chinese healthy men

Andrology, Volume 14, Issue 2, Page 466-479, February 2026.
Abstract Objectives This study aimed to evaluate the pharmacodynamic effects of administering tunodafil hydrochloride with alcohol on blood pressure and heart rate in healthy Chinese males, and to investigate the mutual pharmacokinetic interactions and safety of the combination.
Dingyuan Hu, Suping Niu, Fan Huang, Lu Jin, Qun Gu, Yanting Li, Chongyou Lee, Zhenwei Xie, Xiangxing Liu, Fang Men, Wenyan Zhao, Shuang Li, Yian Liu, Qian Wang, Huaying Fan, Jiaojiao Zhang, Shuangshuang Lin, Liming Chen, Yi Fang   +18 more
wiley   +1 more source

Proteomic profiling of porcine seminal extracellular vesicles reveals potential in vivo fertility biomarkers

Andrology, Volume 14, Issue 2, Page 555-570, February 2026.
Abstract Background Predicting male fertility in farm animals remains a challenge. Seminal plasma (SP) contains a high amount of heterogeneous seminal extracellular vesicles (sEVs), believed involved in reproductive processes and maybe key to understanding male fertility.
Isabel Barranco, Pablo Martínez‐Díaz, Ana Parra, María José Martínez‐Alborcia, Xiomara Lucas, Heriberto Rodríguez‐Martínez, Jordi Roca   +6 more
wiley   +1 more source

Efficacy and safety of short- and long-term, regular and on-demand regimens of phosphodiesterase type 5 inhibitors in treating erectile dysfunction after nerve-sparing radical prostatectomy: a systematic review and meta-analysis

, 2017
D Tian, X Wang, Huan Zong, Y Zhang
openalex   +1 more source

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In Defense of Phosphodiesterase 5 Inhibitors

JAMA Ophthalmology, 2022
Not ...
Belladelli, Federico, Del Giudice, Francesco, Eisenberg, Michael L   +2 more
openaire   +3 more sources

Phosphodiesterase-5 Inhibitors: Future Perspectives

Current Pharmaceutical Design, 2009
PDE-5 inhibitors were originally studied in cardiovascular indications but were later developed and approved for on-demand treatment of erectile dysfunction (ED). A few years ago sildenafil was approved for the treatment of pulmonary hypertension, thus renewing interest in cardiovascular applications, and tadalafil became available in once-daily ...
Giannitsas, Konstantinos, Perimenis, Petros   +1 more
openaire   +2 more sources

Phosphodiesterase-5 Inhibitors

2013
Nitric oxide (NO) signaling plays a key role in modulating vascular tone and remodeling in the pulmonary circulation. The guanylate cyclase/cyclic guanylate monophosphate-signaling pathway primarily mediates nitric oxide signaling. This pathway is critical in normal regulation of the pulmonary vasculature, and is an important target for therapy in ...
Barbara A, Cockrill, Aaron B, Waxman
openaire   +2 more sources

Phosphodiesterase 5 Inhibitors from Derris scandens

Planta Medica, 2018
AbstractPhosphodiesterase 5 inhibitors have been used as a first-line medicine for the treatment of erectile dysfunction. In the search for new phosphodiesterase 5 inhibitors from natural sources, we found that the 95% ethanol extract of Derris scandens stem showed phosphodiesterase 5 inhibitory activity with an IC50 value of about 7 µg/mL.
Nattiya, Chaichamnong, Prapapan, Temkitthawon, Nantaka, Khorana, Prompan, Pitpakdeeanan, Pornnarin, Taepavarapruk, Nitra, Nuengchamnong, Yuthana, Siriwattanasathien, Apichart, Suksamrarn, Kornkanok, Ingkaninan   +8 more
openaire   +2 more sources