Results 61 to 70 of about 12,220,634 (288)
Portopulmonary hypertension practice patterns after liver transplantation
Liver Transplantation, EarlyView., 2022 Abstract Portopulmonary hypertension (POPH) is a type of pulmonary arterial hypertension occurring exclusively in those with portal hypertensive liver disease. Liver transplantation (LT) can significantly improve outcomes. Current guidelines counsel against immediate adjustments to targeted therapy after LT and suggest routine echocardiography as ...
Arun Jose +3 more
wiley +1 more source
UroThe management of erectile dysfunction (ED) shows several gray zones, especially in terms of patients’ satisfaction and adherence to the treatment. The main and first-line treatment for ED is drug therapy, mainly phosphodiesterase-5 inhibitors (PDE5is ...
Carlos Miacola +9 more
doaj +1 more source
Рациональная фармакотерапия в кардиологии, 2016 About 150 million men worldwide and about 50% of men aged 40-88 y.o. in outpatient practice suffer from erectile dysfunction (ED). There is a linear relation between the age and ED rate. The main reason of ED in the majority of men (about 80% of patients)
M. N. Mamedov +3 more
doaj +1 more source
Antioxidant effects of phosphodiesterase-5 inhibitors: reply [PDF]
Cardiovascular Research, 2013 We thank Dr. Tanus-Santos for his interest in our study.1 The study by Muniz et al .2 found that erectile dysfunction patients with the lowest levels of endogenous nitric oxide (NO) have the best responses to the phosphodiesterase-5 (PDE5) inhibitor sildenafil.
Rui, Zhang, Zhi-Cheng, Jing
openaire +2 more sources
Phosphodiesterase Type 5 Inhibitors, Sport and Doping [PDF]
, 2017 Phosphodiesterase type 5 inhibitors (PDE5i) (e.g., sildenafil, tadalafil, vardenafil, and avanafil) are drugs commonly used to treat erectile dysfunction, pulmonary arterial hypertension, and benign prostatic hyperplasia.
Duranti, Guglielmo +17 more
core +1 more source
Advanced Science, EarlyView.Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong +8 more
wiley +1 more source
Phosphodiesterase 5 inhibitors in male sexual dysfunction.
, 2003 PURPOSE OF REVIEW Phosphodiesterase 5 inhibitors are preferred by most men for the oral treatment of erectile dysfunction. In many guidelines, this therapy is recommended as first-line therapy because of convenience, high efficacy, and low rates of side ...
Kuthe A
core +1 more source
Enviromics and Abiotic Enviromics: Enhancing Stress Biology and Plant Resilience Breeding
Advanced Science, EarlyView.Environmental stressors are captured through high‐throughput envirotyping and integrated into an enviromic framework with genomic, transcriptomic, phenomic, and environmental data. AI/ML models enable prediction and guide marker‐assisted selection, genomic selection, genome editing, and gene pyramiding toward improved abiotic stress tolerance, yield ...
Guangchao Sun +6 more
wiley +1 more source
Asian Journal of Andrology, 2015 The study was to compare treatment preference, efficacy, and tolerability of sildenafil citrate (sildenafil) and tadalafil for treating erectile dysfunction (ED) in Chinese men naοve to phosphodiesterase 5 (PDE5) inhibitor therapies.
Wen-Jun Bai +9 more
doaj +1 more source
Cyclic Guanosine Monophosphate Signaling and Phosphodiesterase-5 Inhibitors in Cardioprotection [PDF]
, 2012 Cyclic guanosine monophosphate (cGMP) is an important intracellular second messenger that mediates multiple tissue and cellular responses. The cGMP pathway is a key element in the pathophysiology of the heart and its modulation by drugs such as ...
Das, Anindita +2 more
core +1 more source