Results 111 to 120 of about 87,967 (330)
Advances in the treatment of Raynaud’s phenomenon
Terri L LevienDrug Information Pharmacist and Clinical Associate Professor, College of Pharmacy, Washington State University Spokane, WA, USAAbstract: Raynaud’s phenomenon is a common condition characterized by vasospasm of the digital arteries
Terri L Levien
doaj
The Effects of Cyclic Nucleotide Phosphodiesterase Inhibitors on Ejaculated Porcine Spermatozoan Metabolism1 [PDF]
David L. Garbers+3 more
openalex +1 more source
What Does Iron Mean to an Oligodendrocyte?
Iron is essential for oligodendrocyte (OL) biology and myelin production, with deficiencies leading to severe neurological impairments. Understanding iron trafficking in OLs is crucial for developing treatments for dysmyelinating conditions. ABSTRACT Iron is essential for life and plays a key role in multiple fundamental cellular functions.
Quinn W. Wade, James R. Connor
wiley +1 more source
Anti-inflammatory effects of theophylline and selective phosphodiesterase inhibitors
Theophylline has been used in the treatment of airway diseases, for more than 50 years with benefit thought to be derived from its ability to elicit bronchodilatation.
Katharine H. Banner, Clive P. Page
doaj +1 more source
Binding of inhibitor alters kinetic and physical properties of extracellular cyclic AMP phosphodiesterase from Dictyostelium discoideum. [PDF]
Richard H. Kessin+3 more
openalex +1 more source
Cardiac Uses of Phosphodiesterase-5 Inhibitors
Phosphodiesterase-5 inhibitors (PDE5Is) improve erectile function by enhancing nitric oxide availability in the penis and its supplying vasculature, resulting in vasodilation and increased blood flow. PDE5Is might benefit cardiovascular diseases because phosphodiesterase-5 is also located elsewhere in the body, including the pulmonary and systemic ...
Bryan G. Schwartz+5 more
openaire +3 more sources
Diverse Subpopulations of Reactive Astrocytes Following Chronic Toxoplasma Infection
Toxoplasma infection results in distinct astrocyte subpopulations. Chronically labeled reactive astrocytes appear transcriptionally plastic and can regain acute inflammatory responding and naive homeostatic astrocytic gene patterns in the presence of ongoing neuroinflammation.
Zoe A. Figueroa+7 more
wiley +1 more source
Besides the mainstay of α-blockers and 5α-reductase inhibitors, other forms of medical therapy complete the armamentarium in the treatment of lower urinary tract symptoms (LUTS) in men.
Kok Kit Ng, Foo Cheong Ng
doaj
The objective of the current study is to evaluate the phosphodiesterase inhibitory activity of flavonoids using in silico docking studies. In silico docking studies were carried out using AutoDock 4.2, based on the Lamarckian genetic algorithm principle.
Arumugam Madeswaran+5 more
doaj +1 more source
Use of Phosphodiesterase Inhibitors in the Postoperative Period of Skin Flaps: A Systematic Review. [PDF]
Daronch OT+3 more
europepmc +1 more source