Results 191 to 200 of about 87,967 (330)

Therapeutic Potential of Phosphodiesterase Inhibitors against Neurodegeneration: The Perspective of the Medicinal Chemist. [PDF]

ACS Chem Neurosci, 2020
Ribaudo G, Ongaro A, Zagotto G, Memo M, Gianoncelli A.   +4 more
europepmc   +1 more source

KS-619-1, a new inhibitor of Ca2+ and calmodulin-dependent cyclic nucleotide phosphodiesterase from Streptomyces californicus.

, 1987
Yuzuru Matsuda, Hiroshi Kase
openalex   +2 more sources

Phosphorylation and activation of phosphodiesterase type 3B (PDE3B) in adipocytes in response to serine/threonine phosphatase inhibitors: deactivation of PDE3B in vitro by protein phosphatase type 2A [PDF]

, 1999
Svante Resjö, Alina Oknianska, Stanisław Zołnierowicz, Vincent C. Manganiello, Eva Degerman   +4 more
openalex   +1 more source

Human hypoxia models in aerospace medicine: Potential applications for human pharmacological research

British Journal of Clinical Pharmacology, EarlyView.
Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post, Cayla Denney, Adam Cohen, Jens Jordan, Ulrich Limper   +4 more
wiley   +1 more source

Phosphodiesterase Inhibitors for Alzheimer's Disease: A Systematic Review of Clinical Trials and Epidemiology with a Mechanistic Rationale. [PDF]

J Alzheimers Dis Rep, 2020
Sanders O, Rajagopal L.
europepmc   +1 more source

Griseolic acid, an inhibitor of cyclic adenosine 3',5'-monophosphate phosphodiesterase. II. The structure of griseolic acid.

, 1985
Shuji Takahashi, Fumio Nakagawa, Kayoko Kawazoe, Yoji Furukawa, Sadao Sato, Chihiro Tamura, Atsushi Naito   +6 more
openalex   +2 more sources

Evidence that cyclic AMP phosphodiesterase inhibitors suppress TNFα generation from human monocytes by interacting with a ‘low‐affinity’ phosphodiesterase 4 conformer [PDF]

, 1996
John E. Souness, Miriam Griffin, Christopher Maslen, Karen Ebsworth, Lisa C. Scott, Kenneth H. Pollock, Malcolm N. Palfreyman, Jan‐Anders Karlsson   +7 more
openalex   +1 more source

Magnetic resonance imaging‐guided transurethral ultrasound ablation for benign prostatic obstruction: 1‐year clinical outcomes of a phase II study

BJU International, EarlyView.
Objectives To evaluate the safety and efficacy of magnetic resonance imaging (MRI)‐guided transurethral ultrasound ablation (TULSA) as a minimally invasive alternative for benign prostatic obstruction (BPO). Patients and Methods This prospective, single‐centre, early phase II study (NCT03350529) included 30 men with BPO scheduled for primary ...
Antti Viitala, Mikael Anttinen, Pietari Mäkelä, Heikki Pärssinen, Pertti Nurminen, Teija Sainio, Jani Saunavaara, Pekka Taimen, Roberto Blanco Sequeiros, Peter J. Boström   +9 more
wiley   +1 more source

The use of phosphodiesterase inhibitors in the treatment of female sexual dysfunction: scoping review. [PDF]

Rev Bras Ginecol Obstet
Martins JCC, Lucas ARCA, Costa JMM.
europepmc   +1 more source

The effect of two phosphodiesterase inhibitors on bone healing in mandibular fractures (animal study in rats). [PDF]

J Korean Assoc Oral Maxillofac Surg, 2020
MalekiGorji M, Golestaneh A, Razavi SM.
europepmc   +1 more source